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Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker
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Chapter 59: Antiemetic Agents

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Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker | Registered Nurse (RN) School Study Aid

Chapter 59: Antiemetic Agents
6 Picmonics to Learn | 10 mins
Ondansetron
Indications
Postoperative Vomiting
Chemotherapy-induced Nausea and Vomiting
Mechanism
5-HT3 Serotonergic Antagonist
Centrally-acting Antiemetic
Side Effects
Headache
Constipation
QT Prolongation
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1 min
Chlorpromazine (Thorazine)
Mechanism
Low Potency Antipsychotic
Indications
Schizophrenia
Hiccups
Side Effects
Sedation
Weight Gain
Orthostatic Hypotension
Anticholinergic Effects
QT Prolongation
Neuroendocrine Effects
Caution in Seizure Patients
Corneal Deposits
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2 mins
Metoclopramide
Indications
Antiemetic
Promotility Agent
Mechanism
Increased Resting Tone
Antagonist at D2 Receptor
Side Effects
Parkinsonian Symptoms
Galactorrhea
Contraindication
Small Bowel Obstruction
Parkinson's Disease
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2 mins
Anticholinergics
B.O.AT.S Acronym
Benztropine
Parkinson's Disease
Oxybutynin
Decrease bladder spasms
Atropine
Mydriasis and Cycloplegia
Scopolamine
Motion Sickness
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1 min
Promethazine (Phenergan)
Mechanism
Histamine H1 Receptor Antagonist
Weak Dopamine Antagonist
Indications
Nausea and Vomiting
Motion Sickness
Side Effects
Respiratory Depression
Sedation
Anticholinergic Effects
Extrapyramidal Symptoms
Considerations
Use Large Bore IV
Monitor for Tissue Necrosis
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2 mins
First Generation Antihistamines
Mechanism of Action
Histamine H1 Receptor Antagonist
Indications
Allergies
Nausea and Vomiting
Motion Sickness
Anaphylaxis
Drug Names
Diphenhydramine (Benadryl)
Promethazine (Phenergan)
Chlorpheniramine
Side Effects
Sedation
Anticholinergic Effects
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2 mins

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