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Neurology - Stroke
Types of Strokes
Warning Signs
Transient Ischemic Attack (TIA)
Reversible Ischemic Neurologic Deficit (RIND)
Types
Ischemic
Thrombotic
Atherosclerosis
Embolic
Atrial Fibrillation
Hemorrhagic
Severe Hypertension
3 mins
Circle of Willis
Characteristics
Anterior Cerebral Artery (ACA) Supplies Motor/Sensory Parts of the Cortex for Lower Extremities
Anterior Communicating Artery (Acomm) Connects ACA to ACA
Internal Carotid Arteries (ICA)
Middle Cerebral Arteries (MCA) Supply Cortex for Upper Limbs and Face
Posterior Communicating Artery (Pcomm) Connects ICA to PCA
CHA2DS2-VASc for Stroke Risk in Atrial Fibrillation
CHF (+1)
Hypertension (+1)
Age 75 + (+2)
Diabetes (+1)
Stroke or TIA or Thromboembolism History (+2)
Vascular Disease (+1)
Age 65-75 Years (+1)
Sex Female (+1)
Interpretation
0 = No Anticoagulation
1 = Consider Anticoagulation
2 = Anticoagulation
3 mins
Alteplase
Mechanism
Tissue Plasminogen Activator
Indications
Thrombosis
Side Effects
Bleeding
Contraindications
Intracranial Hemorrhage
Internal Hemorrhaging
Considerations
Minimize Bleeding
Monitor for Shock
Antidote
Aminocaproic Acid
2 mins
Aspirin
Indications
Fever
Pain and Headache
Cardiovascular Disease (CAD)
Mechanism of Action
Irreversible inhibition of COX-1 and COX-2
Suppress Thromboxanes and Prostaglandins
NSAID
Side Effects
Reye's Syndrome
Tinnitus
Peptic Ulceration
Mixed Acidosis/Alkalosis
Nephropathy
2 mins
Clopidogrel (Plavix)
Mechanism
ADP Receptor Antagonist
Prevent Platelet Aggregation
Indications
Acute Coronary Syndrome (ACS)
Prevention of Thrombotic Events
Side Effects
Bleeding
Thrombotic Thrombocytopenic Purpura (TTP)
Pancytopenia
Abdominal Pain
Considerations
Withhold Before Surgery
2 mins
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