Nora Shared "Pharm Test 3" - 55 Picmonics
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Pharm Test 3
Bile Acid Resins
- Indications
- Hyperlipidemia
- Mechanism of Action
- Bile Acid Reabsorption Prevented
- Slight Increase HDL/Triglycerides
- Decrease LDL
- Drugs
- Colestipol (Colestid)
- Cholestyramine
- Colesevelam
- Side Effects
- Cholesterol Gallstones
- Decreased Absorption of Fat-soluble Vitamins
- Patients Hate It
2 mins
Bile Acid Resins
- Indications
- Hyperlipidemia
- Mechanism of Action
- Bile Acid Reabsorption Prevented
- Decrease LDL
- Drugs
- Colestipol (Colestid)
- Cholestyramine (Questran)
- Colesevelam (Welchol)
- Side Effects
- GI Distress
- Cholesterol Gallstones
- Decreased Absorption of Fat-soluble Vitamins
2 mins
Cholesterol Lab Values
- LDL (Low Density Cholesterol)
- < 100 mg/dL
- HDL (High Density Cholesterol)
- > 40 mg/dL Males
- > 50 mg/dL Females
- Total Cholesterol
- < 200 mg/dL
1 min
Vitamin B3 - Niacin (Nicotinic Acid)
- Mechanism
- Decreases Triglycerides
- Decreases LDL
- Increases HDL
- Indications
- Dyslipidemia
- Pellagra
- Diarrhea
- Dermatitis
- Dementia
- Side Effects
- Flushing
- GI Distress
- Hepatotoxicity
2 mins
Atorvastatin (Lipitor)
- Characteristics
- -statin Suffix
- Mechanism
- HMG-CoA Reductase Inhibitors
- Indications
- High Cholesterol
- Side Effects
- Hepatotoxicity
- Rash
- Rhabdomyolysis
- Myopathy
- Considerations
- Monitor Liver Enzymes
- Administer at Bedtime
- Avoid Grapefruit
2 mins
Gemfibrozil (Fibrates)
- Mechanism of Action
- Decreases Triglycerides
- Increase in HDL
- Slight Decrease in LDL
- Indications
- Hypertriglyceridemia
- Side Effect
- Hepatotoxicity
- Cholesterol Gallstones
- Myopathy
- Considerations
- Do Not Combine with Statins
- Warfarin Toxicity
2 mins
Ezetimibe
- Indications
- Hyperlipidemia
- Mechanism of Action
- Cholesterol Absorption Blocker
- Decreases LDL
- Side Effects
- Diarrhea
- Increased LFT Values
1 min
Fibrates
- Indications
- Hyperlipidemia
- Mechanism of Action
- Upregulate LPL
- Decreases Triglycerides
- Slight Increase in HDL
- Slight Decrease in LDL
- Side Effect
- Hepatotoxicity
- Cholesterol Gallstones
1 min
Statins
- Rhabdomyolysis
- Hepatotoxicity
- HMG-CoA reductase inhibitors
- Decrease LDL
- Decrease Triglycerides
- Increase HDL
2 mins
Mannitol (Osmitrol)
- Mechanism
- Osmotic Diuresis
- Indications
- Reducing Intracranial Pressure
- Reducing Intraocular Pressure
- Renal Failure Prophylaxis
- Side Effects
- Edema
- Fluid and Electrolyte Imbalance
- Considerations
- Avoid Use in Cardiac Patients
- IV Administration
2 mins
Loop Diuretics
- Mechanism of Action
- Thick Ascending Limb of Loop of Henle
- Inhibits Na+-K+-2Cl-
- Sulfa Drug
- Drug Names
- Furosemide
- Lasix
- Side Effects
- Ototoxicity from Rapid Injection
- Gout
- Dehydration
- Hypocalcemia
- Hypokalemia
- Orthostatic Hypotension
2 mins
Loop Diuretic Education
- Furosemide (Lasix)
- Indications
- Heart Failure
- Pulmonary Edema
- Acute Renal Failure (ARF)
- Edema
- Education
- Notify the provider of weakness, dizziness, or muscle cramping
- Increase Potassium Intake
- Check BP Daily
- Daily Weights and Monitor IandOs
1 min
Ethacrynic Acid
- Mechanism of Action
- Non-sulfa Drug
- Phenoxyacetic Acid Derivative
- Loop Diuretic
- Inhibits Na+-K+-2Cl- Cotransporter
- Thick Ascending Loop of Henle
- Clinical Use
- Diuresis
- Side Effects
- Hypokalemia
- Ototoxicity
- Gout
2 mins
Hydrochlorothiazide HCTZ
- Mechanism of Action
- Inhibits Reabsorption NaCl and H2O
- Indications
- Edema
- Mild to Moderate Hypertension
- Side Effects
- Hypokalemia
- Hyponatremia
- Dehydration
- Hyperglycemia
- Gout
- Contraindications
- Sulfa Allergy
- Pregnancy and Breastfeeding
1 min
Spironolactone (Aldactone)
- Mechanisms
- Inhibition of Aldosterone
- Potassium Retention
- Indications
- Hypertension
- Edema
- Heart Failure
- Side Effects
- Hyperkalemia
- Endocrine Effects
- Consideration
- Avoid Potassium Supplements
2 mins
Hyponatremia
- Assessment
- < 135 mEq Na+
- Nausea and Vomiting
- Decreased LOC
- Confusion / Lethargy
- Seizures
- Priority Interventions
- Assess Airway
- Reduce Diuretic Dosage
- Fluid Excess Hyponatremia
- Mannitol (Osmitrol)
- Fluid Restriction
- Fluid Deficit Hyponatremia
- Hypertonic Solution (3% or 5% NaCl)
2 mins
Hypernatremia
- Assessment
- > 145 mEq/L Na+
- Change in LOC
- Extreme Thirst
- Orthostatic Hypotension
- Dry Flushed Skin
- Muscle Twitching
- Seizures
- Priority Interventions
- Treat and Prevent Dehydration
- Hypotonic Solutions (0.225% or 0.45% NaCl)
- Sodium Restriction
- Diuretics
2 mins
Hyperkalemia
- Assessment
- > 5.0 mEq/L K+
- Abdominal Cramps
- Muscle Weakness
- Diarrhea
- Arrhythmia
- Tall, Peaked T Waves
- Interventions
- IV Calcium
- Infusion of Glucose and Insulin
- Loop or Thiazide Diuretics
- Kayexalate
- Dialysis
- Prevention Education
2 mins
Hypokalemia
- Assessment
- < 3.5 mEq/L
- Muscle Weakness
- Arrhythmia
- U Wave
- Ileus
- Hyporeflexia
- Interventions
- IV K+ Infusion at 5-10 mEq/hr
- Give Orally with Food
- Nursing Considerations
- Monitor Respiratory Status
3 mins
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Pharmacologic Interventions
- Diuretics
- Hypertonic IV Fluids
- Demeclocycline
- Tolvaptan and Conivaptan
1 min
