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Gram Postive Bacteria
Actinomyces Israelii
Characteristics
Gram-Positive
Bacillus
Anaerobe
Branching
Oral Flora
Dental Work
Oral Trauma
Associated with IUDs
Signs and Symptoms
GU Infections
Draining Sinus Tract
Facial Abscess
Yellow Sulfur Granules
Treatment
Penicillin
2 mins
Bacillus Anthracis (Anthrax) Disease
Signs and Symptoms
Cutaneous
Painless Black Eschar (Necrotic Lesion)
Pulmonary
Mediastinal Widening
Rapidly Fatal
Woolsorter's Disease
Gastrointestinal
Consuming Anthrax-infected Meat
2 mins
Bacillus Anthracis (Anthrax) Characteristics
Characteristics
Gram-Positive
Spore-Forming
D-glutamate Polypeptide Capsule
Protective Antigen
Lethal Toxin
Edema Factor
Increased cAMP
1 min
Bacillus Cereus Characteristics
Gram-Positive
Bacilli
Endospore Forming
B Hemolytic
Toxins and Enterotoxins
Reheated Rice
1 min
Bacillus Cereus Disease
Signs and Symptoms
Emetic Form
Short Incubation (1-6 Hours)
Nausea and Vomiting
Diarrheal Form
Long Incubation (8-16 Hours)
Diarrhea and GI Pain
2 mins
Clostridium botulinum
Characteristics
Bacillus
Gram-positive
Anaerobe
Spore-forming
Heat Labile Toxin
Inhibits Acetylcholine (Ach) Release at Neuromuscular Junction (NMJ)
Canned Food in Adults
Spores in Honey
Signs and Symptoms
Descending Flaccid Paralysis
Diplopia
Ptosis
Floppy Baby
Constipation
2 mins
Clostridium perfringens
Characteristics
Gram-Positive
Bacillus
Anaerobe
Spore-Forming
Alpha Toxin Lecithinase
Phospholipase
Heat Labile Enterotoxin
Signs and Symptoms
Myonecrosis
Gas Gangrene
Food Poisoning and Diarrhea
Treatment
Hyperbaric O2 Chamber
2 mins
Clostridioides difficile (Clostridium difficile)
Characteristics
Gram-Positive
Bacillus
Anaerobe
Clindamycin and Ampicillin
Toxin A Enterotoxin
Damages Brush Border of Gut
Toxin B Cytotoxin
Damages Cytoskeletal Structure
Signs and Symptoms
Diarrhea
Pseudomembranous Colitis
Toxic Megacolon
Diagnosis
Detect Toxins in Stool
Treatment
Metronidazole
Vancomycin
3 mins
Clostridium tetani
Characteristics
Gram-Positive
Bacilli
Obligate Anaerobic
Exotoxin
Spore-Forming
Renshaw Cells in the Spinal Cord
Blocks Glycine and GABA Release
Signs and Symptoms
Spasms
Risus Sardonicus
Lockjaw
Opisthotonus
3 mins
Corynebacterium diphtheriae
Characteristics
Gram-Positive
Bacillus
Exotoxin
ADP Ribosylation of Elongation Factor 2
Beta Prophage
Lysogeny
Tellurite Agar
Chinese Letters
Metachromatic Blue Red Granules
Aniline Stains Deeply Methylene Blue
Signs and Symptoms
Pseudomembranous Pharyngitis
Lymphadenopathy
Myocarditis
Polyneuritis
3 mins
Enterococci
Characteristics
Gram-Positive Cocci
Catalase Negative
6.5% NaCl
Grows in Bile
Normal Colonic Flora
Signs and Symptoms
Urinary Tract Infection
Subacute Endocarditis
Penicillin Resistant
VRE (Vancomycin Resistant Enterococci)
2 mins
Listeria Monocytogenes Disease
Signs and Symptoms
Soft Cheese
Pregnant Women Have Flu-Like Symptoms
Pregnant Women Have GI Symptoms
Granulomatosis Infantiseptica
Spontaneous Abortion
Meningitis
Monocytes in CSF
Treatment
Ampicillin
2 mins
Listeria Monocytogenes Characteristics
Characteristics
Gram Positive
Bacillus
Intracellular
Survives in Cold Temperature
Actin Rocket
Tumbling Motility
Catalase-Positive
Beta-Hemolytic
Only Gram-Positive with Endotoxin-Like Structure
2 mins
Mycobacterium leprae
Characteristics
Acid-Fast
Aerobic
Likes Cool Temperature
Diagnosis by Skin Biopsy or PCR
Lepromatous Leprosy
Th2 Response
Leonine Facies
Tuberculoid Leprosy
TH1 Response
Hypoesthetic Skin Plaques
Granulomatous Response
Treatment
Dapsone
Rifampin
Clofazimine
2 mins
Mycobacterium Tuberculosis Characteristics
Characteristics
Mycolic Acid Cell Wall
Acid-fast
Carbolfuchsin Stain Red
Lowenstein-Jensen Agar
Serpentine Cord Factor
Primary TB
Primary TB
Caseating Granuloma
Ghon Focus
Hilar Lymph Nodes
Ghon Complex
Reactivation TB
Reactivation TB
Reactivation in Apex
3 mins
Nocardia
Characteristics
Aerobic
Gram-Positive
Catalase-Positive
Urease-Positive
Acid Fast
Branching
Beaded Filament
AIDS/Immunocompromised
Soil
Signs and Symptoms
Lung Cavitation
Brain Abscess
Kidney Abscess
Treatment
TMP-SMX
2 mins
Staphylococcus aureus Characteristics
Characteristics
Gram-Positive
Cocci
Catalase-Positive
Coagulase-Positive
Beta-Hemolytic
Protein A Virulence Factor
Inhibits Phagocytosis
MRSA
Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
2 mins
Staphylococcus aureus Disease
Skin Infections
Impetigo
Abscesses
Exfoliative Toxin
Scalded Skin Syndrome
Toxic Shock Syndrome (TSST 1)
Binds to MHC II and T Cell Receptor
Food Poisoning
Acute Bacterial Endocarditis
Pneumonia
Osteomyelitis
2 mins
Staphylococcus epidermidis
Characteristics
Cocci
Gram-Positive
Catalase-Positive
Urease-Positive
Coagulase-Negative
Novobiocin-Sensitive
Component of Normal Skin Flora
Infects Prosthetic Devices and IV Catheters
Contaminates Blood Cultures
Produces Adherent Biofilms
2 mins
Staphylococcus saprophyticus
Characteristics
Gram-Positive
Cocci
Catalase-Positive
Coagulase-Negative
Novobiocin-Resistant
Urease-Positive
Disease
Urinary Tract Infections (UTI's)
1 min
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