Anna Shared "Pharm Exam 1 Drugs" - 24 Picmonics
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Pharm Exam 1 Drugs
Acyclovir (Zovirax)
- Mechanism
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Indications
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Side Effects (Oral)
- Headache
- GI Distress
- Side Effects (IV)
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Considerations
- Prevents Recurrent Episodes
- Slow IV Infusion
2 mins
Aminoglycoside Overview
- End in "-mycin"
- GNATS
- Gentamicin
- Neomycin
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Indications
- Severe Gram Negative Infections
- Bowel Surgery Prep
1 min
Aminoglycoside Side Effects
- Side Effects
- Ototoxicity
- Nephrotoxicity
- Respiratory Paralysis
- Contraindications
- Pregnancy
- Considerations
- Peak and Trough
- Never Mix with Penicillin in Same IV
2 mins
Ampicillin and Amoxicillin
- Mechanism
- Aminopenicillin
- Broad Spectrum Penicillin
- Indications
- Gram-Positive and Some Gram-Negative Infections
- Side Effects
- Rash
- Diarrhea
- Considerations
- No Effect Against Staph Aureus
- Often combined with Beta Lactamase Inhibitor
- Allergic Reaction
2 mins
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
Aztreonam (Azactam)
- Mechanism
- Monobactam Antibiotic
- Bactericidal
- Indications
- Gram-Negative Infections
- No Activity on Gram-Positives or Anaerobes
- Side Effects
- Blood Dyscrasias
- Pain at Injection Site
- Considerations
- Safe for Penicillin Allergy
- Synergistic with Aminoglycosides
- Nebulizer Form Available
2 mins
Cephalosporins
- Starts with "Cef-"
- Mechanism of Action
- Bactericidal
- Indications
- Gram-Positive and Gram-Negative Infections
- Side Effects
- Allergic Reactions
- Thrombophlebitis
- Bleeding
- Contraindications
- Renal Impairment
- Considerations
- Avoid IV Calcium with Ceftriaxone
- No Alcohol
2 mins
Chloramphenicol (Chloromycetin)
- Mechanism
- Bacteriostatic
- Indications
- Gram Positive or Gram Negative Infections
- Side Effects
- Bone Marrow Suppression
- Aplastic Crisis
- Gray Syndrome
- Considerations
- Toxicity Limits Use
- Monitor Blood Counts
2 mins
Clindamycin
- Mechanism
- Bacteriostatic
- Binds 50S Ribosomal Subunit
- Indications
- Gram-Positive Infections
- Anaerobic Infections
- Side Effects
- Rash
- Pseudomembranous Colitis
- C. Difficile (Associated Diarrhea)
- Arrhythmias
- Blood Dyscrasias
- Considerations
- Monitor for Diarrhea
3 mins
Fluoroquinolones
- End in "-floxacin"
- Mechanism of Action
- Bactericidal
- Indications
- Variety of Infections
- Side Effects
- GI Distress
- Photosensitivity
- Achilles Tendon Rupture
- Contraindications
- Pregnancy
- Children
- Myasthenia Gravis
- Considerations
- Avoid Milk Products or Antacids
- Slow IV Infusion
2 mins
Imipenem and Meropenem (Carbapenems)
- Mechanism
- Carbapenems
- Broad-spectrum Antibiotic
- Bactericidal
- Indications
- Gram Positive and Gram Negative Infections
- Side Effects
- GI Distress
- Suprainfections
- Seizures
- Considerations
- Penicillin Allergy
- IV or IM Route
- Imipenem Combined with Cilastatin
3 mins
Linezolid (Zyvox)
- Mechanism Of Action
- Oxazolidinone Antibiotic
- Binds 23S rRNA of 50S Subunit
- Inhibits Protein Synthesis
- Indication
- Gram-Positive Organisms
- MRSA
- VRE (Vancomycin Resistant Enterococci)
- Side Effects
- Bone Marrow Suppression
- Decreased Platelet Count
- Peripheral Neuropathy
- Lactic Acidosis
- Serotonin Syndrome
- Considerations & Patient Education
- Avoid Tyramine Containing Foods
4 mins
Macrolides
- End in "-thromycin"
- Mechanism of Action
- Bacteriostatic
- Indications
- Alternative for Penicillin Allergy
- Respiratory Infections
- Pneumonia
- Side Effects
- QT Prolongation and Sudden Death
- C.Diff Overgrowth
- GI Distress
- Considerations
- Slow IV Infusion
2 mins
Penicillin
- Mechanism of Action
- Weakens Cell Wall
- Indications
- Gram-Positive Infections
- Prophylaxis
- Side Effects
- Pain at IM Injection Site
- Allergic Reaction
- Considerations
- Skin Tests
- Allergy ID
- Medication Education
2 mins
Sulfonamides
- Mechanism of Action
- Bacteriostatic
- Indications
- Urinary Tract Infection
- Side Effects
- Crystalluria
- Photosensitivity
- Hemolytic Anemia
- Kernicterus
- Rash
- Considerations
- Sulfa Allergy
- Encourage Fluids
2 mins
Tetracycline Toxicities
- Inhibition of Bone Growth in Children
- Teratogen
- Discoloration of Teeth
- Photosensitivity
- GI Distress
2 mins
Tetracyclines Overview
- End in "-cycline"
- Mechanism of Action
- Bacteriostatic
- Indications
- Infectious Diseases
- Acne
- Periodontal Disease
- Nursing Considerations
- Avoid Milk, Antacids, Iron
- Sunlight Protection
1 min
Tetracyclines Side Effects
- Side Effects
- Superinfection
- Clostridioides difficile
- Discoloration of Teeth
- Bone Deformities
- Photosensitivity
- Contraindications
- Children Under 8
- Pregnancy
1 min
Tigecycline (Tygacil)
- Mechanism Of Action
- Glycylcycline Antibiotic
- Binds 30S Subunit
- Inhibits Protein Synthesis
- Indications
- Severe Infections
- Broad Spectrum Coverage
- Anaerobic & Multidrug-Resistant Organisms
- Deep Tissue Penetration
- Side Effects
- GI Distress
- Severe Nausea and Vomiting
- Considerations
- 2nd Line Agent
3 mins
Vancomycin Side Effects & Toxicity
- Side Effects
- Thrombophlebitis
- Nephrotoxicity
- Ototoxicity
- Diffuse Flushing Called Red Man Syndrome
- Prevent with Antihistamine
- Prevent with Slow Infusion
2 mins
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