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Conrad Shared "CPR Pharmacology" - 58 Picmonics

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CPR Pharmacology

ACE Inhibitor Toxicity
CAPTOPRIL Mnemonic
Cough
Angioedema
Potassium Changes (Hyperkalemia)
Taste Change
Hypotension
Pregnancy Changes
Rash
Increased Renin
Lower Angiotensin II
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2 mins
ACE Inhibitors
-Pril Suffix
Indications
Hypertension
CHF
Diabetic Nephropathy
Mechanism of Action
Inhibits ACE
Decreases GFR
Inhibits Constriction of Efferent Arteriole
Side Effect
Increased Bradykinin
Cough
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1 min
Acetazolamide
Indications
Glaucoma
Altitude Sickness
Pseudotumor Cerebri
CHF
Metabolic Alkalosis
Mechanism of Action
Carbonic Anhydrase Inhibitor
Sodium Bicarbonate (NaHCO3) Diuresis
Side Effects
Metabolic Acidosis
Paresthesias
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1 min
Alpha 1 Receptor
Characteristics
Gq Subunit
Increase Vascular Smooth Muscle Contraction
Increase Pupillary Dilator Muscle Contraction
Increase Intestinal and Bladder Sphincter Muscle Contraction
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1 min
Alpha 2 Receptor
Characteristics
Gi Subunit
Decrease Sympathetic Outflow
Decrease Insulin Release
Decrease Lipolysis
Increase Platelet Aggregation
Decrease Aqueous Humor Production
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2 mins
Alpha Agonists
-RINE suffix
Norepinephrine
Hypotension
Phenylephrine
Hypotension
Congestion
Ephedrine
Congestion
Urinary Incontinence
Hypotension
Epinephrine
Anaphylaxis and Asthma
Hypotension
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1 min
Alpha-2 Agonists (Sympathoplegics)
Indications
Hypertension
Renal disease
Mechanism of Action
Centrally acting Alpha-2 Agonist
Drugs
Clonidine
Rebound Hypertension
Alpha-Methyldopa
Pregnancy
Coombs (+) Hemolytic Anemia
SLE Like Syndrome
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2 mins
Amphetamine Antidote
Antidote
Ammonium Chloride (NH4Cl)
Acidify Urine
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34 secs
Amphotericin B
Indications
Systemic Mycosis
Fungal Meningitis
Last Resort for Protozoan infections
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
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1 min
Amphotericin B Side Effects & Toxicity
Side Effects
Fever/Chills "Shake and Bake"
Nephrotoxicity
Milder with Liposomes
Hypotension
Anemia
IV Phlebitis
Arrhythmias
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1 min
Angiotensin Receptor Blockers (ARBs)
-sartan suffix
Indications
Hypertension
CHF
Diabetic Nephropathy
Mechanism of Action
Angiotensin II Receptor Blockers
Side Effect
Hyperkalemia
Contraindication
Pregnancy
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1 min
Beta Blocker Antidote
Antidote
Glucagon
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29 secs
Beta-1 Agonists
Dobutamine
Heart Failure
Cardiac Stress Test
Isoproterenol
Bradyarrhythmias
Torsades de Pointes
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58 secs
Beta-1 Receptor
Characteristics
Gs Protein Class
Increased Heart Rate
Increased Contractility
Increase Renin Release
Increased Lipolysis
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44 secs
Beta-2 Agonists
Short-term Treatment
Terbutaline
Asthma
Tocolysis
Albuterol
Asthma
Long-term Treatment
Salmeterol
Asthma
Chronic Obstructive Pulmonary Disease (COPD)
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3 mins
Beta-2 Receptor
Characteristics
Gs protein class
Increased Heart Rate
Increased Contractility
Increased Lipolysis
Increased Insulin
Increased Aqueous Humor Production
Ciliary Muscle Relaxation
Vasodilation
Bronchodilation
Decrease Uterine Tone
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2 mins
Bile Acid Resins
Indications
Hyperlipidemia
Mechanism of Action
Bile Acid Reabsorption Prevented
Slight Increase HDL/Triglycerides
Decrease LDL
Drugs
Colestipol (Colestid)
Cholestyramine
Colesevelam
Side Effects
Cholesterol Gallstones
Decreased Absorption of Fat-soluble Vitamins
Patients Hate It
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2 mins
Cardiovascular Effects of Beta-Blockers
Cardiac Myocytes and Vasculature
Decrease cAMP
Decreases SA and AV Node Conduction Velocity
Lower Blood Pressure
Decrease O2 Consumption
Decreases Mortality Post-MI
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2 mins
Class I Antiarrhythmics (Na+ Channel Blockers) Overview
Indications
Arrhythmias
Local Anesthesia
Mechanism of Action
Block or Slow Conduction
Block Na+ Channels
Raise Threshold
State Dependent
Contraindication
Hyperkalemia
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1 min
Class IA Antiarrhythmics (Na+ Channel Blockers)
Indications
Arrhythmias
Mechanism of Action
Increase AP, ERP, and QT interval.
Drugs
Disopyramide
Procainamide
Drug-induced Lupus
Quinidine
Cinchonism
Shared Side Effects
Thrombocytopenia
Torsades de Pointes
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1 min

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