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Autoantibody to the Presynaptic Calcium Channel on Motor Neurons
Inhibits Acetylcholine (ACh) Release at Neuromuscular Junction
Paraneoplastic Syndrome
Small Cell Lung Cancer
Symptoms
Proximal Muscle Weakness
Improves with Muscle Use
Autonomic Symptoms
Extraocular Muscle Sparing
2 mins
Chemical Synapse
Voltage-Gated Calcium Channels Open
Ca2+ Influx
Vesicle-Membrane Fusion
Exocytosis of Neurotransmitter
Neurotransmitter Binds Post-Synaptic Receptors
Neurotransmitter Breakdown
Neurotransmitter Reuptake
1 min
Neck and Shoulder Muscles
Superficial
Splenius Capitis
Trapezius
Rhomboid Minor
Rhomboid Major
Deltoid
Latissimus Dorsi
Levator Scapulae
Deep
Supraspinatus
Infraspinatus
Teres Minor
Teres Major
2 mins
Back Muscles
Superficial
Latissimus Dorsi
External Oblique
Internal Oblique
Gluteus Medius
Gluteus Maximus
Deep
Erector Spinae
Serratus Anterior
Serratus Posterior
2 mins
Myasthenia Gravis
Mechanism
Antibodies to Acetylcholine Receptor
Symptoms
Ptosis
Diplopia
Weakness with Muscle Use
Respiratory Death
Thymus Associated
Treatment
Acetylcholinesterase Inhibitors
Plasmapheresis
Thymectomy
1 min
Norepinephrine
Mechanism of Action
Alpha Agonist
Beta1 Agonist
Indications
Hypotension
Side Effect
Decreases Renal Blood Flow
1 min
Dermatomes - Cervical
C2 - Posterior Cap Distribution
C3 - High Turtleneck
C4 - Low Collar Shirt
C5 - Anterolateral Shoulder
C6 - Thumb
C7 - Middle Finger
C8 - Pinky Finger
1 min
CN XI
Accessory Nerve
Motor
Head Turning
Shoulder Shrugging
36 secs
Guillain-Barre Syndrome Assessment
Assessment
Ascending Paralysis
Muscle Weakness
Paresthesias (Pins and Needles)
Diplopia
Difficulty Speaking
Dysphagia
Labile Blood Pressure
Loss of Bowel and Bladder Control
Considerations
Aggressive Airway Management
2 mins
Somatic Reflex Arc
Spinal Cord
Sensory (Afferent) Neuron
Interneurons Transmit
Motor (Efferent) Neuron
Effector Targets
1 min
Hyperkalemia
Assessment
> 5.0 mEq/L K+
Abdominal Cramps
Muscle Weakness
Diarrhea
Arrhythmia
Tall, Peaked T Waves
Interventions
IV Calcium
Infusion of Glucose and Insulin
Loop or Thiazide Diuretics
Kayexalate
Dialysis
Prevention Education
2 mins
Lumbar Puncture
Indications
CSF Sample
CSF Pressure
Considerations
Empty Bladder
Side-lying Position
Between 3rd and 4th Lumbar Vertebrae
Number Tubes
Supine Position After Procedure
Contraindications
Increased ICP (Intracranial Pressure)
Infection at Puncture Site
2 mins
Herniated Disc (Nucleus Pulposus)
Cause/Mechanism
Spine Trauma
Natural Degeneration
Spinal Stenosis
Assessment
Pain
Weakness
Urinary and Fecal Incontinence
Interventions
Brace
Medications
Outpatient Procedures
Surgery
2 mins
Alpha 1 Receptor
Characteristics
Gq Subunit
Increase Vascular Smooth Muscle Contraction
Increase Pupillary Dilator Muscle Contraction
Increase Intestinal and Bladder Sphincter Muscle Contraction
1 min
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