Jonathan Shared "Pharm Block 1" - 81 Picmonics
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Pharm Block 1
Steroid Hormones
- Characteristics
- Nuclear Membrane
- Long-Lived and Slow-Acting
- Cholesterol-Derived
- Intracellular Receptors
- DNA Transcription
- Examples
- Testosterone
- Aldosterone
- Estrogen
- Cortisol
2 mins
Alpha 1 Receptor
- Characteristics
- Gq Subunit
- Increase Vascular Smooth Muscle Contraction
- Increase Pupillary Dilator Muscle Contraction
- Increase Intestinal and Bladder Sphincter Muscle Contraction
1 min
Alpha 2 Receptor
- Characteristics
- Gi Subunit
- Decrease Sympathetic Outflow
- Decrease Insulin Release
- Decrease Lipolysis
- Increase Platelet Aggregation
- Decrease Aqueous Humor Production
2 mins
Beta-1 Receptor
- Characteristics
- Gs Protein Class
- Increased Heart Rate
- Increased Contractility
- Increase Renin Release
- Increased Lipolysis
44 secs
Beta-2 Receptor
- Characteristics
- Gs Protein Class
- Cardiopulmonary
- Increased Heart Rate
- Increased Contractility
- Bronchodilation
- Metabolic
- Increased Lipolysis
- Increased Insulin
- Increased Glycogenolysis
- Increased Cellular Potassium Uptake
- Considerations
- Increased Aqueous Humor Production
- Vasodilation
- Decrease Uterine Tone
2 mins
Direct Cholinomimetics
- Muscarinic Agonists
- Bethanechol
- Bladder and Bowels
- Methacholine
- Bronchoconstriction
- Pilocarpine
- Contracts Ciliary Muscle and Pupillary Sphincter
- Carbachol
- Releases Intraocular Pressure
1 min
Sjögren’s Syndrome
- Mechanism
- Autoimmune Exocrine Gland Destruction
- Symptoms (Classic Triad)
- Xerostomia
- Xerophthalmia
- Arthritis
- Diagnosis
- Anti SS-B (La)
- Anti SS-A (Ro)
- Schirmer's Test
- Salivary Gland Biopsy
- Treatment
- Symptomatic Treatment
- Complications
- Lymphoma
- Other
- Sicca Syndrome
4 mins
Indirect Cholinomimetics
- Acetylcholinesterase Inhibitors
- Doesn't Cross BBB
- Edrophonium
- Myasthenia Gravis (Diagnosis)
- Pyridostigmine and Neostigmine
- Myasthenia Gravis (Tx)
- Ileus
- Crosses BBB
- Physostigmine
- Atropine Overdose
- Glaucoma
- Donepezil
- Alzheimer's
2 mins
Donepezil
- Indications
- Alzheimer's Disease
- Mechanism of Action
- Acetylcholinesterase Inhibitor
- Increased Acetylcholine
- Side Effects
- Nausea and Vomiting
- Dizziness
52 secs
Acetylcholinesterase Inhibitor Antidote
- Antidote
- Atropine
- Pralidoxime
1 min
Acetylcholinesterase Inhibitor Poisoning
- DUMBBELSS
- Diarrhea
- Urination
- Miosis
- Bronchospasm
- Bradycardia
- Emesis
- Lacrimation
- Salivation
- Sweating
2 mins
Anticholinergics
- B.O.AT.S Acronym
- Benztropine
- Parkinson's Disease
- Oxybutynin
- Decrease bladder spasms
- Atropine
- Mydriasis and Cycloplegia
- Scopolamine
- Motion Sickness
1 min
Anticholinergics Continued
- Drugs
- Glycopyrrolate
- Reduces Airway Secretions
- Ulcer Treatment
- Ipratropium
- Asthma and C.O.P.D
- Dicyclomine
- Hyoscyamine
- Irritable Bowel Syndrome
1 min
Atropine
- Indications
- Blocks DUMBBeLSS
- Bradycardia
- Side Effects
- Skin Flushing
- Increased Temperature
- Dry Mouth
- Cycloplegia
- Disorientation
- Mydriasis
1 min
Nondepolarizing Neuromuscular Blocking Drugs
- Names Include "Cur"
- Competitive Antagonists
- Acetylcholine Competition
- Reversal of Blockade
- Neostigmine, Edrophonium
1 min
Succinylcholine
- Indications
- Inducing Paralysis
- Mechanism of Action
- Neuromuscular Blocking Drugs
- Motor Nicotinic Receptor
- ACh Receptor Agonist
- Depolarization
- Phases of Action
- Phase I (Paralysis Non-reversible)
- Phase II (Paralysis Reversible)
- Neostigmine (Reversal Agent)
2 mins
Closed-Angle Glaucoma
- Primary
- Lens causes pupillary obstruction
- Aqueous humor builds behind iris
- Iris bends forward, obstructing trabecular mesh
- Secondary
- Hypoxia Causes Neovascular Proliferation
- Contraction and obstruction of trabecular mesh
- Chronic disease (Crone)
- Asymptomatic
- Acute Disease
- Eye pain and blindness
- Rock-hard eye
- Headache
- Emergency
- Epinephrine contraindicated
2 mins
Open-Angle Glaucoma
- Humor Has Access to Trabecular Meshwork
- Presentation
- Painless
- African American
- Elderly
- Positive Family History
- Primary Open-Angle Glaucoma
- Most Common Form of Glaucoma
- Unknown Mechanism
- Secondary Open-Angle Glaucoma
- Blocked Trabecular Meshwork (With Open-Angle)
- WBCs
- Red Blood Cells (RBC)
- Retinal Products
2 mins
Autonomic Nervous System
- Characteristics
- Sympathetic Nervous System
- Fight or Flight
- All Preganglionic Neurons Release Acetylcholine
- Sympathetic Postganglionic Neurons Release Norepinephrine
- Antagonistic Effects of Sympathetic and Parasympathetic Nervous Systems
- Parasympathetic Nervous System
- Rest and Digest
- Parasympathetic Postganglionic Neurons Release Acetylcholine
2 mins
Alpha Agonists
- -RINE suffix
- Norepinephrine
- Hypotension
- Phenylephrine
- Hypotension
- Congestion
- Ephedrine
- Congestion
- Urinary Incontinence
- Hypotension
- Epinephrine
- Anaphylaxis and Asthma
- Hypotension
1 min
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