Matthew Shared "Step" - 57 Picmonics
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Step
Craniopharyngioma
- Hypopituitarism
- Remnants of Rathke's Pouch
- Tooth-enamel Like Calcification
- Cholesterol Crystals
- Yellow Viscous Fluid
- Headache
- Bitemporal Hemianopsia
1 min
Pilocytic Astrocytoma
- Occurs Most Commonly in Kids
- Posterior Fossa
- Cerebellum
- Well Circumscribed
- GFAP
- Rosenthal Fibers
- Eosinophilic Corkscrew Fibers
1 min
Ependymoma
- Occur in Children
- Fourth Ventricle
- Hydrocephalus
- Perivascular Pseudorosettes
- Rod Shaped Blepharoplasts
- Cauda Equina in Adults
- Poor Prognosis
- Neurofibromatosis Type II
2 mins
Oligodendroglioma
- Slow growing tumor
- Frontal lobe
- Chicken Wire Pattern
- Fried egg appearance
- Calcifications
32 secs
Schwannoma
- Characteristics
- Acoustic Schwannoma
- Cranial Nerve VIII
- Cerebellopontine Angle
- S100 Positive
- Bilateral Schwannoma in Neurofibromatosis Type 2
- Tinnitus
- Cranial Nerve V
- Affects Corneal Reflex
2 mins
Glioblastoma Multiforme
- Most Common Malignant Primary Brain Tumor
- Grade 4 Astrocytoma
- Can Cross Corpus Callosum
- Butterfly Glioma
- Pseudo-palisading Tumor Cells
- Areas of Necrosis and Hemorrhage
- Stain Astrocytes for Glial Fibrillary Acidic Protein (GFAP)
- Grave Prognosis
2 mins
Hemangioblastoma
- Most Often Cerebellar
- Associated with Von Hippel-Lindau
- Retinal Angiomas
- Can Produce EPO
- Secondary Polycythemia
- Foamy Cells
- High Vascularity
59 secs
Medulloblastoma
- Pathophysiology
- Occurs in Children
- Cerebellum
- Fourth Ventricle
- Diagnosis
- Small Blue Cells
- Lots of Mitotic Figures
- Homer Wright Rosettes
- Signs and Symptoms
- Hydrocephalus
- Ataxia
- Wide-based Gait
- Treatment
- Radiosensitive
2 mins
Meningioma
- Epidemiology
- Most Common Adult Primary Brain Tumor
- pathology
- Benign
- Originate from Arachnoid Villi
- Dural Attachment
- Parasagittal
- Clinical Manifestations
- Contralateral Leg Weakness
- Seizures
- Diagnosis
- Psammoma Bodies
- Calcifications
- Increased Bone Density
3 mins
Pinealoma
- Pathophysiology
- Melatonin
- Superior Colliculi
- Obstructs Cerebral Aqueduct
- Signs and Symptoms
- Obstructive Hydrocephalus
- Vomiting
- Parinaud's Syndrome
- Paralysis of Upward Gaze
- Setting Sun Sign
- Increased Beta-hCG
- Precocious Puberty
2 mins
11 Beta-Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Decreased Aldosterone
- Increased Sex Hormones
- Increased 11 Deoxycorticosterone (11 DOC)
- Signs and Symptoms
- Hypertension
- Masculinization
1 min
21 Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Increased 17 Hydroxyprogesterone
- Decreased Aldosterone
- Signs and Symptoms
- Hypotension
- Increased Renin
- Hyperkalemia
- Female Pseudohermaphroditism
2 mins
17 Alpha Hydroxylase Deficiency
- Decreased Cortisol
- Decreased Sex Hormones
- Increased Mineralocorticoids (DOC)
- Hypertension
- Hypokalemia
- XY Externally Phenotypic Female
- No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
- XX Externally Phenotypic Female
- Sexual Infantilism
2 mins
Burkitt's Lymphoma
- Adolescents or young adults
- C-myc gene moves next to heavy chain Ig gene
- T 8;14
- Starry sky appearance
- Sheets of lymphocytes with interspersed macrophages
- Jaw lesion in endemic (African) form
- Pelvis or abdomen in non endemic form (American form)
- Associated with EBV
2 mins
Follicular Lymphoma
- Derives from Germinal Center
- Occurs in adults
- T14;18
- BCL 2 overexpression
- BCL 2 inhibits apoptosis
- Indolent
- Generalized lymphadenopathy
- Bone marrow involvement
2 mins
Mantle Cell Lymphoma
- Older Males
- Activation of Cyclin D Gene
- T 11;14
- CD5
- Poor Prognosis
55 secs
Adult T Cell Lymphoma
- Caused by HTLV 1
- Japan, West Africa, Caribbean
- Present with cutaneous lesions
- Aggressive
1 min
Diffuse Large B Cell Lymphoma
- Epidemiology
- Most Common Non-Hodgkin’s Lymphoma
- Usually in Older Adults
- 20% in Children
- Features
- May be Mature T Cell in Origin
- Derives from Germinal Center
- GI Tract and Brain
2 mins
Hodgkin Lymphoma Signs & Symptoms
- Signs and Symptoms
- Localized Single Group of Lymph Nodes
- Contiguous Spread
- Constitutional B Symptoms
- Low-Grade Fever
- Night Sweats
- Weight Loss
2 mins
Hodgkin Lymphoma Pathophysiology
- Pathophysiology
- Reed-Sternberg Cells
- Binucleate
- Owl's Eyes Appearance
- CD 15 and CD 30
- B Cell Origin
- Bimodal Age Distribution
2 mins
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