Jeff Shared "GI-TBL" - 33 Picmonics
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GI-TBL
Aminoglycosides
- Drug Names
- Gentamicin
- Neomycin for Bowel Surgery Prep
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Inhibit Formation of Initiation Complex
- Cause Misreading of mRNA
- Require O2 for Uptake
- Resistance
- Resistance by Transferase Enzymes
- Acetylation
- Phosphorylation
- Adenylation
- Indications
- Gram-Negative Rod Infections
- Synergistic with B-Lactam Antibiotics
- Side Effects
- Nephrotoxicity Especially When Used with Cephalosporins
- Ototoxicity Especially When Used with Loop Diuretics
- Teratogen
5 mins
Bacillus Cereus Characteristics
- Gram-Positive
- Bacilli
- Endospore Forming
- B Hemolytic
- Toxins and Enterotoxins
- Reheated Rice
1 min
Bacillus Cereus Disease
- Signs and Symptoms
- Emetic Form
- Short Incubation (1-6 Hours)
- Nausea and Vomiting
- Diarrheal Form
- Long Incubation (8-16 Hours)
- Diarrhea and GI Pain
2 mins
Campylobacter jejuni
- Characteristics
- Gram-Negative
- Bacillus
- Flagella
- Curved
- Corkscrew Appearance
- Oxidase-Positive
- Grows Well at 42 Degrees
- Undercooked Meat
- Unpasteurized Milk
- Animals with Diarrhea
- Signs and Symptoms
- Bloody Diarrhea
- Guillain-Barre syndrome
- Reactive Arthritis
3 mins
Clostridioides difficile (Clostridium difficile)
- Characteristics
- Gram-Positive
- Bacillus
- Anaerobe
- Clindamycin and Ampicillin
- Toxin A Enterotoxin
- Damages Brush Border of Gut
- Toxin B Cytotoxin
- Damages Cytoskeletal Structure
- Signs and Symptoms
- Diarrhea
- Pseudomembranous Colitis
- Toxic Megacolon
- Diagnosis
- Detect Toxins in Stool
- Treatment
- Metronidazole
- Vancomycin
3 mins
Clostridium perfringens
- Characteristics
- Gram-Positive
- Bacillus
- Anaerobe
- Spore-Forming
- Alpha Toxin Lecithinase
- Phospholipase
- Heat Labile Enterotoxin
- Signs and Symptoms
- Myonecrosis
- Gas Gangrene
- Food Poisoning and Diarrhea
- Treatment
- Hyperbaric O2 Chamber
2 mins
Cryptosporidium
- Characteristics
- Protozoa
- Ingestion of Oocysts in Food or Water
- Acid Fast Cysts
- Signs and Symptoms
- Outbreaks of Diarrhea from Contaminated Water Supply
- Mild Disease in Non-immunocompromised
- Severe Diarrhea in AIDS
- Treatment
- Nitazoxanide for Immunocompetent
2 mins
E. coli Overview
- Characteristics
- Gram-Negative
- Bacillus
- Purple Colony with Metallic Green Sheen
- Lactose-Fermenting
- Pink on MacConkey Agar
- Disease
- Diarrhea
- Lipid A Septic Shock
- P Pili Pyelonephritis and Cystitis
- K Capsule Neonatal Meningitis
- K Capsule Pneumonia
- H Antigen Flagella
2 mins
Entamoeba histolytica
- Pathophysiology
- Protozoa
- Amebiasis
- Ingestion of Cysts in Food and Water
- Signs and Symptoms
- Bloody Diarrhea
- Flask-Shaped Ulcer
- Liver Abscess
- Anchovy Paste
- RUQ Pain
- Diagnosis
- RBCs in Cytoplasm of Trophozoite
- Cyst With Four Nuclei
- Treatment
- Metronidazole
- Iodoquinol
3 mins
Enterohemorrhagic E. Coli (EHEC)
- Characteristics
- O157:H7
- Non-Sorbitol Fermenting
- Hamburger Meat
- Produces Shiga-like Toxin
- Gram-negative
- Lysogeny
- Inactivates 60S Ribosome
- Disease
- Bloody Diarrhea
- Hemolytic Uremic Syndrome (HUS)
- Hemolytic Anemia
- Acute Renal Failure
- Thrombocytopenia
2 mins
Fluoroquinolones Antibiotics
- -floxacin
- Mechanism of Action
- Inhibits Topoisomerase II & IV
- Bactericidal
- Indications
- Gram-negative Rods
- Pneumonia
- Gastrointestinal Infections
- Urinary Tract Infection
- Genital Infections
- Drugs
- Levofloxacin
- Ciprofloxacin
- Has Pseudomonas Coverage
- Considerations
- Avoid Polyvalent Cations
3 mins
Fluoroquinolones Toxicities
- Diarrhea
- Skin Rash
- Headache
- Tendon Rupture in Adults
- Myalgias in Kids
- Damage to Cartilage
- Teratogen
- QT Prolongation
1 min
Giardia lamblia
- Characteristics
- Protozoa
- Ingestion of Cysts
- Seen in Campers
- Daycare Centers
- Mental Hospitals
- Infects Small Intestine
- Signs and Symptoms
- Bloating
- Flatulence
- Fatty Diarrhea
- Diagnosis
- Crescent-shaped Protozoa Adjacent to Epithelial Brush Border
- Predisposed if Low IgA
- Treatment
- Metronidazole
3 mins
Listeria Monocytogenes Characteristics
- Characteristics
- Gram Positive
- Bacillus
- Intracellular
- Survives in Cold Temperature
- Actin Rocket
- Tumbling Motility
- Catalase-Positive
- Beta-Hemolytic
- Only Gram-Positive with Endotoxin-Like Structure
2 mins
Listeria Monocytogenes Disease
- Signs and Symptoms
- Soft Cheese
- Pregnant Women Have Flu-Like Symptoms
- Pregnant Women Have GI Symptoms
- Granulomatosis Infantiseptica
- Spontaneous Abortion
- Meningitis
- Monocytes in CSF
- Treatment
- Ampicillin
2 mins
Macrolides
- Mechanism of Action
- Bacteriostatic
- Bind to 23S rRNA of 50S Subunit
- Inhibit Protein Synthesis by Blocking Translocation
- Macrolides
- Erythromycin
- Azithromycin
- Clarithromycin
- Indications
- Gram-Positive Cocci
- Atypical Pneumonia
- Chlamydia
- Considerations
- Resistance by Methylation of 23S rRNA Binding
2 mins
Macrolides Side Effects
- Side Effects
- Diarrhea
- Prolonged QT Interval
- P450 Inhibitor
- Cholestatic Hepatitis
- Skin Rash
- Eosinophilia
3 mins
Metronidazole
- Mechanism of Action
- Bactericidal
- Forms Free Radical Toxic Metabolites
- Damages DNA
- Indications
- Giardia lamblia
- Entamoeba Histolytica
- Trichomonas
- Gardnerella
- Anaerobes
- Side Effects
- Metallic taste
- Disulfiram like Reaction with Alcohol
2 mins
Opioids Overview
- Indications
- Pain
- Weaning
- Cough
- Diarrhea
- Mechanism of Action
- Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
- Decrease Synaptic Transmission
- Side Effects
- Respiratory Depression
- Addiction
- Miosis
- Constipation
2 mins
Salmonella Enterica Spp.
- Characteristics
- Animal and Human Reservoir
- Poultry and Eggs
- Turtles
- PMN Immune Response
- Symptoms
- Gastroenteritis
- Diarrhea
- Possibly Bloody
- Treatments
- No Antibiotics
- No Vaccine Available
2 mins
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