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pharm exam 7
Acyclovir (Zovirax)
Mechanism
Guanosine Analog
Inhibits Viral Replication
Thymidine Kinase Activation
Indications
Herpes Simplex Virus (HSV)
Varicella Zoster Virus (VZV)
Side Effects (Oral)
Headache
GI Distress
Side Effects (IV)
CNS Toxicity
Nephrotoxicity (Crystalline Nephropathy)
Considerations
Prevents Recurrent Episodes
Slow IV Infusion
2 mins
Terbinafine
Indications
Dermatophytosis
Onychomycosis
Mechanism
Inhibits Squalene Epoxidase
Side Effects
Hepatotoxicity
GI Distress
Taste Disturbances
Headache
2 mins
Nystatin
Indications
Candidiasis
Vaginal
Oral
Cutaneous
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
Topical form of Amphotericin B
Side Effects
Rash
1 min
Amphotericin B
Indications
Systemic Mycosis
Fungal Meningitis
Last Resort for Protozoan infections
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
1 min
Rubeola (Measles)
Mechanism
Virus
Signs and Symptoms
Fever
Red Maculopapular Rash
3 C's
Photophobia
Koplik Spots
Considerations
MMR Vaccination
Antipyretics
Vitamin A Supplementation
2 mins
Influenza
Assessment
High Fever
Cough
Headache
Muscle Aches
Chills
Intervention
Vaccination
Drug Therapy
Zanamivir (Relenza)
Oseltamivir (Tamiflu)
2 mins
Amphotericin B Side Effects & Toxicity
Side Effects
Fever/Chills "Shake and Bake"
Nephrotoxicity
Milder with Liposomes
Hypotension
Anemia
IV Phlebitis
Arrhythmias
1 min
Propylthiouracil (PTU) and Methimazole (MMI)
Indications
Hyperthyroidism
Mechanism
Inhibits Thyroid Peroxidase
PTU Blocks Peripheral Conversion of T4 to T3
Side Effects
Agranulocytosis
Skin Rash
Hepatotoxicity (PTU)
Teratogen (MMI)
1 min
Levothyroxine (Synthroid)
Mechanism
Synthetic T4
Indications
Hypothyroidism
Side Effects
Thyrotoxicosis
Tremors
Heat Intolerance
Insomnia
Tachycardia
Considerations
Do Not Use for Obesity
TSH Monitoring
2 mins
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