Aaron Shared "Pathoma 9: Respiratory Tract Pathology" - 19 Picmonics
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Pathoma 9: Respiratory Tract Pathology
Mycobacterium Tuberculosis Characteristics
- Characteristics
- Mycolic Acid Cell Wall
- Acid-fast
- Carbolfuchsin Stain Red
- Lowenstein-Jensen Agar
- Serpentine Cord Factor
- Primary TB
- Primary TB
- Caseating Granuloma
- Ghon Focus
- Hilar Lymph Nodes
- Ghon Complex
- Reactivation TB
- Reactivation TB
- Reactivation in Apex
3 mins
Ghon Complex
- Calcified Focus of Infection
- Hilar Lymph Nodes
- Primary Tuberculosis
- Typically in Children
1 min
Obstructive Lung Disease
- Blocked Airflow
- Increased residual volume
- V/Q Mismatch
- Decreased forced vital capacity (FVC)
- Decreased FEV1/FVC ratio
- Asthma
- Bronchiectasis
- Chronic bronchitis
- Emphysema
51 secs
Chronic Bronchitis
- Pathophysiology
- Chronic Inflammation of Bronchi
- Signs and Symptoms
- Early-Onset Cyanosis
- Blue Bloaters
- Productive Cough
- Wheezing
- Chronic Obstructive Pulmonary Disease (COPD)
- Late-Onset Dyspnea
- Crackles
- Diagnosis
- Reid Index > 50%
2 mins
Emphysema
- Clinical Features
- Pink Puffer
- Exhale through Pursed Lips
- Barrel Chest
- Pathophysiology
- Obstructive Lung Disease
- Increased Lung Compliance
- Types
- Centriacinar
- Panacinar
2 mins
Asthma
- Obstructive lung disease
- Bronchial Hyperresponsiveness
- History of Atopic Disease
- Beta2 agonists
- Corticosteroids
- Curschmann's spirals
- Hypertrophy of smooth muscle
- Reversible
- Charcot Leyden crystals
- Methacholine challenge
- Wheezing
- Cough
- Initially decreased PaCO2
- Pulsus paradoxus
2 mins
Bronchiectasis
- Obstructive Lung Disease
- Chronic Necrotizing Infection
- Permanent Airway Dilation
- Poor Ciliary Motility
- Kartagener's Syndrome
- Cystic Fibrosis
- Allergic Bronchopulmonary Aspergillosis
- Hemoptysis
- Increased Sputum
2 mins
Restrictive vs. Obstructive Lung Diseases
- Restrictive Lung Disease
- Decreased Lung Volume
- FEV1/FVC Ratio Normal to Increased
- Obstructive Lung Disease
- Increased Lung Volume
- Decreased FEV1/FVC Ratio
2 mins
Restrictive Lung Diseases
- Poor Breathing Mechanics
- Interstitial Lung Diseases
- Goodpasture's Syndrome
- Eosinophilic Granuloma
- Granulomatosis with Polyangiitis
- Sarcoidosis
- Pneumoconiosis
- Idiopathic Pulmonary Fibrosis
- Drug Toxicity
- Acute Respiratory Distress Syndrome (ARDS)
- Neonatal Respiratory Distress Syndrome
2 mins
Sarcoidosis Symptoms
- Black Females
- Symptoms
- Asymptomatic
- Uveitis
- Interstitial Fibrosis
- Erythema Nodosum
- Hepatomegaly
- Myocardial Sarcoidosis
- Lupus Pernio
1 min
Sarcoidosis Characteristics and Labs
- Mechanism
- Unknown Mechanism
- Immune-Mediated
- Noncaseating Granulomas
- Vitamin D Activation
- Labs
- Hypercalcemia
- Elevated ACE
- Asteroid and Schaumann Bodies
- Bronchoalveolar Lavage shows Increased CD4:CD8 Ratio
- X-ray Shows Bilateral Hilar Lymphadenopathy
- Treatment
- Corticosteroids
2 mins
Acute Respiratory Distress Syndrome (ARDS) Assessment
- Cause
- Damaged Alveolar-Capillary Membrane
- Assessment
- Restlessness
- Dyspnea
- Refractory Hypoxemia
- Decreased PaO2
- Diffuse Pulmonary Infiltrates
- Atelectasis
- Pulmonary Hypertension
2 mins
Acute Respiratory Distress Syndrome (ARDS) Interventions
- Interventions
- Closely Monitor Patient
- ABG's (Arterial Blood Gases)
- Oxygen
- Assess for O2 Toxicity
- Mechanical Ventilation
- PEEP
- Assess for Pneumothorax
- Permissive Hypercapnia
- Considerations
- High Mortality Rate
2 mins
Neonatal Respiratory Distress Syndrome
- Cause/Mechanism
- Fetal Lung Immaturity
- Lack of Surfactant
- Assessment
- Respiratory Distress
- Nasal Flaring
- Retractions
- Grunting
- Interventions
- Surfactant
- Oxygen
- Mechanical Ventilation
- Considerations
- Total Parenteral Nutrition (TPN)
2 mins
Small Cell (Oat Cell) Carcinoma
- Characteristics
- Aggressively Malignant
- Strong Correlation with Smoking
- Central Location
- Amplification of Myc Oncogenes
- Signs and Symptoms
- Narrowing of Bronchial Airways
- Cushing's Syndrome
- Ectopic ACTH
- Syndrome Of Inappropriate Antidiuretic Hormone (SIADH)
- Lambert-Eaton Syndrome
- Diagnosis
- Kulchitsky Cells
- Neuron-Specific Enolase Positive
- Chromogranin A Positive
- Treatment
- Chemotherapy and Radiation
3 mins
Squamous Cell Carcinoma of the Lung
- Characteristics
- Strong Correlation with Smoking
- More Common in Men
- Central Location
- Cavitating Lesion Extending to Hilum
- PTHrP Causes Hypercalcemia
- Diagnosis
- Keratin Pearls
- Intercellular Bridges
- Treatment
- Surgical Resection (if Early Stage)
- Chemotherapy and Radiation (if Later Stage)
2 mins
Adenocarcinoma of the Lung
- Characteristics
- Most Common Lung Cancer
- Most Common in Nonsmokers
- Peripheral Location
- KRAS, EGFR, and ALK Mutations
- Diagnosis
- Glandular Pattern
- Often Stains with Mucin
- Clinical Features
- Presents with Hemoptysis
- Clubbing
- Treatment
- Surgical Resection
- Chemotherapy and Radiation
2 mins
Large Cell Carcinoma
- Characteristics
- Strong Correlation with Smoking
- Poor Prognosis
- Peripheral Lesions
- Symptoms
- Gynecomastia
- Galactorrhea
- Diagnosis
- Anaplastic Cells
- Pleomorphic Giant Cells
- May Produce Beta hCG
- Diagnosis of Exclusion
- Treatment
- Surgical Resection
- Less Responsive to Chemotherapy and Radiation
2 mins
Bronchial Carcinoid Tumor
- Characteristics
- Excellent Prognosis
- Signs and Symptoms
- Symptoms of Bronchial Obstruction
- Often Asymptomatic
- Carcinoid Syndrome
- Diarrhea
- Wheezing
- Flushing
- Diagnosis
- 5-HIAA in Urine
- Nests of Neuroendocrine Cells
- Chromogranin A Positive
- Treatment
- Surgical Resection
- Octreotide for Symptomatic Relief
2 mins
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