Virginia Shared "Pharmacology 1- class 8" - 16 Picmonics
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Pharmacology 1- class 8
Celecoxib
- Indications
- Rheumatoid Arthritis
- Osteoarthritis
- Pain
- Mechanism of Action
- NSAID
- Selectively Inhibits COX-2
- Side Effects
- Sulfa Allergy
- Increased Risk of Thrombosis
- GI Bleed
- Contraindication
- Pregnancy > 30 Weeks
1 min
Cyclosporine (Sandimmune) Overview
- Mechanism
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Prevent Transplant Rejection
- Psoriasis
- Rheumatoid Arthritis
- Considerations
- Monitor Plasma Levels
- Avoid Grapefruit Juice
- Increased Risk of Lymphoma
2 mins
Cyclosporine (Sandimmune) Side Effects
- Side Effects
- Nephrotoxicity
- Hepatotoxicity
- Infection
- Hypertension
- Hirsutism
- Tremor
- Hyperkalemia
- Hypomagnesemia
- Gingival Hyperplasia
1 min
Phenobarbital (Barbiturates)
- Mechanism
- Barbiturate
- Indications
- Seizures
- Side Effects
- Ataxia
- Paradoxical Excitement
- Fatigue/Drowsiness
- Considerations
- Monitor Plasma Levels
- High Potential for Abuse
1 min
Lamotrigine (Lamictal)
- Mechanism
- Blocks Na+ Channels
- Indications
- Seizures
- Bipolar Disorder
- Side Effects
- Diplopia
- Stevens-Johnson Syndrome
- Headache
- Aseptic Meningitis
- Nausea and Vomiting
- Considerations
- Screen for Suicide Risk
2 mins
Phenytoin (Dilantin)
- Mechanism
- Blocks Na+ Channels
- Indications
- Tonic-clonic Seizures
- Side Effects
- Ataxia
- Nystagmus
- Sedation
- Gingival Hyperplasia
- Purple Glove Syndrome
- Hirsutism
- Rash
- Anemia
- Considerations
- Individualized Dosing
2 mins
Risperidone (Risperdal)
- Mechanism
- Atypical Antipsychotic
- Indications
- Schizophrenia
- Bipolar Mania
- Autism-Associated Irritability
- Side Effects
- Extrapyramidal Symptoms
- Hyperprolactinemia
- Gynecomastia
- Galactorrhea
- Amenorrhea
- Prolonged QT
- Considerations
- Intramuscular Long Acting (Depot) Form
2 mins
Valproic Acid (Depakote)
- Mechanism
- Blocks Na+ Channels
- Increases GABA Concentration
- Indications
- Tonic-clonic Seizures
- Bipolar Disorder
- Migraine Prophylaxis
- Side Effects
- Hepatotoxicity
- Blood Dyscrasias
- GI Distress
- Tremor
- Pancreatitis
1 min
Carbamazepine (Tegretol)
- Mechanism
- Inactivates Na+ Channels
- Indications
- Seizures
- Bipolar Disorder
- Trigeminal Neuralgia
- Side Effects
- Nystagmus
- Ataxia
- Hepatotoxicity
- Blood Dyscrasias
- Water Retention
- Stevens-Johnson Syndrome
- Considerations
- Avoid Grapefruit Juice
2 mins
Ethosuximide (Zarontin)
- Indications
- First Line Absence Seizure
- Mechanism of Action
- Blocks Thalamic T-Type Ca2+ Channels
- Side Effects
- Stevens-Johnson Syndrome
- Fatigue
- Diarrhea
- Blood Dyscrasias
- Considerations
- Do Not Stop Abruptly
2 mins
Benztropine (Cogentin)
- Mechanism
- Anticholinergic
- Indications
- Parkinson's Disease
- Acute Dystonia
- Side Effects
- Mydriasis
- Dry Mouth
- Urinary Retention
- Tachycardia
- Constipation
- Psychosis
1 min
Parkinson's Drugs
- Parkinsons Characteristics
- Decreased Dopamine
- Increased Acetylcholine
- Drug Names
- BALSA Acronym
- Bromocriptine
- Amantadine
- Levodopa
- Selegiline
- Antimuscarinics
2 mins
Levodopa/Carbidopa (Sinemet)
- Indications
- Parkinson's Disease
- Mechanism of Action
- Increase Dopamine in Brain
- Cross blood-brain barrier
- Increase bioavailability
- Side Effects
- Arrhythmias
- Dyskinesia
1 min
Memantine
- Indications
- Alzheimer's Disease
- Mechanism of Action
- NMDA Receptor Antagonist
- Prevents Excitotoxicity
- Side Effects
- Confusion
- Hallucinations
1 min
Donepezil
- Indications
- Alzheimer's Disease
- Mechanism of Action
- Acetylcholinesterase Inhibitor
- Increased Acetylcholine
- Side Effects
- Nausea and Vomiting
- Dizziness
52 secs
Gabapentin
- Primary Indication
- Seizure Treatment
- Secondary Indications
- Peripheral Neuropathy
- Postherpetic Neuralgia
- Bipolar Disorder
- Migraine Prophylaxis
- Characteristics
- Inhibits Voltage-Gated Ca2+ channels
- Designed as a GABA Analog
- Side Effects
- Ataxia
- Sedation
2 mins
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