Kayla Shared "PHARM B3 L7 Antiparasitic" - 15 Picmonics
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PHARM B3 L7 Antiparasitic
Plasmodium General
- Characteristics
- Protozoa
- Malaria
- Anopheles Mosquito
- Signs and Symptoms
- Cyclic Fever
- Headache
- Anemia
- Splenomegaly
- Diagnosis
- Blood Smear
- Treatment
- Chloroquine
- Mefloquine for Resistant Types
3 mins
Plasmodium Specific
- Malariae
- Fever Every Three Days
- Vivax/Ovale
- Fever Every Two Days
- Duffy Antigen Binding Site
- Duffy often absent in Black Population
- Primaquine treats dormant form in liver
- Falciparum
- Most severe
- Irregular Cycles
- Occludes capillaries in the brain, kidneys, and lungs
4 mins
Clindamycin
- Mechanism of Action
- Bacteriostatic
- Binds 50S Ribosomal Subunit
- Blocks Translocation
- Indications
- Anaerobic Infections above the Diaphragm
- Aspiration Pneumonia
- Lung Abscess
- Side Effects
- Can Cause Pseudomembranous Colitis
1 min
Toxoplasma gondii
- Characteristics
- Protozoa
- Cysts in Meat or Cat Feces
- Signs and Symptoms
- Brain Abscess in HIV Patients
- Ring-enhancing Brain Lesions
- Crosses Placenta in Pregnant Women
- Congenital TORCH Infection
- Treatment
- Pyrimethamine
- Sulfadiazine
2 mins
Sulfonamides Mechanisms
- Bacteriostatic
- Gram-Positive
- Gram-Negative
- Nocardia
- Chlamydia
- PABA antimetabolites
- Inhibit dihydropteroate synthase
- Sulfamethoxazole
- Sulfisoxazole
- Sulfadiazine
1 min
Sulfonamides Side Effects
- Side Effects
- Hypersensitivity
- Nephrotoxicity
- Photosensitivity
- Kernicterus in Infants
- Displaces Warfarin from Albumin
- Considerations
- Hemolysis with G6PD Deficiency
3 mins
Metronidazole
- Mechanism of Action
- Bactericidal
- Forms Free Radical Toxic Metabolites
- Damages DNA
- Indications
- Giardia lamblia
- Entamoeba Histolytica
- Trichomonas
- Gardnerella
- Anaerobes
- Side Effects
- Metallic taste
- Disulfiram like Reaction with Alcohol
2 mins
Macrolides
- Mechanism of Action
- Bacteriostatic
- Bind to 23S rRNA of 50S Subunit
- Inhibit Protein Synthesis by Blocking Translocation
- Macrolides
- Erythromycin
- Azithromycin
- Clarithromycin
- Indications
- Gram-Positive Cocci
- Atypical Pneumonia
- Chlamydia
- Considerations
- Resistance by Methylation of 23S rRNA Binding
2 mins
Echinococcus Granulosus
- Pathophysiology
- Cestode (Tapeworm)
- Ingestion of Eggs from Dog Feces
- Hydatid Cysts in Liver
- Fibrosis and Necrosis
- Anaphylaxis if Antigens Released
- Treatment
- Albendazole
- Surgical Removal
1 min
Taenia Solium
- Pathophysiology
- Cestode (Tapeworm)
- Taeniasis
- Ingestion of Larvae in Undercooked Pork
- Asymptomatic, in Bowels
- Cysticercosis
- Ingestion of Cestode Eggs
- Skin, CNS and Muscles
- Treatment
- Albendazole
- Praziquantel
1 min
Loa Loa
- Pathophysiology
- Nematode (Roundworm)
- Fly Bite
- Calabar Swellings in Skin
- Conjunctiva
- Treatment
- Diethylcarbamazine (DEC)
- Albendazole
1 min
Schistosoma
- Pathophysiology
- Trematode (Fluke)
- Snail-infested Water
- Intense Immune Response
- Intestinal Disease
- Hepatosplenic Granuloma
- Squamous Cell Cancer of the Bladder
- Diagnosis
- Parasitic Antigens via ELISA
- Treatment
- Praziquantel
2 mins
Clonorchis Sinensis
- Pathophysiology
- Trematode (Fluke)
- Undercooked Fish
- Biliary Tract Inflammation
- Pigmented Gallstones
- Associated with Cholangiocarcinoma
- Treatment
- Praziquantel
1 min
Diphyllobothrium Latum
- Pathophysiology
- Cestode (Tapeworm)
- Ingestion of Larvae from Raw Fish
- Competes for Vitamin B12
- Megaloblastic Anemia
- Treatment
- Praziquantel
1 min
NSAIDs
- Indications
- Anti-inflammatory
- Analgesic
- Fever
- Closure of Patent Ductus Arteriosus
- Mechanism of Action
- Reversible Inhibition of COX-1 and COX-2
- Block Prostaglandin Synthesis
- Side Effects
- Interstitial Nephritis
- Gastric Ulcer
- Renal Ischemia
1 min
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