Wen Shared "NUR 600 - Week 7 - Pharmacotherapy for Musculoskeletal and Neurological/Psychological Disorder" - 95 Picmonics
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NUR 600 - Week 7 - Pharmacotherapy for Musculoskeletal and Neurological/Psychological Disorder
NSAIDs
- Indications
- Anti-inflammatory
- Analgesic
- Fever
- Closure of Patent Ductus Arteriosus
- Mechanism of Action
- Reversible Inhibition of COX-1 and COX-2
- Block Prostaglandin Synthesis
- Side Effects
- Interstitial Nephritis
- Gastric Ulcer
- Renal Ischemia
1 min
Aspirin
- Indications
- Fever
- Pain and Headache
- Cardiovascular Disease (CAD)
- Mechanism of Action
- Irreversible inhibition of COX-1 and COX-2
- Suppress Thromboxanes and Prostaglandins
- NSAID
- Side Effects
- Reye's Syndrome
- Tinnitus
- Peptic Ulceration
- Mixed Acidosis/Alkalosis
- Nephropathy
2 mins
Aspirin Poisoning (Salicylism) Assessment
- Early Symptoms
- Nausea and Vomiting
- Tinnitus
- Confusion
- Hyperventilation
- Respiratory Alkalosis
- Late Symptoms
- Metabolic Acidosis
- Coma
- Hyperthermia
1 min
Reye's Syndrome
- Cause
- Aspirin (Salicylates) to Treat Viral Illness (In Children)
- Assessment
- Cerebral Edema
- Lethargy (Decreased LOC)
- Vomiting
- Liver Failure
- Interventions
- Monitor for Increased ICP
- Mannitol (Osmitrol)
- Considerations
- No Aspirin for Children
2 mins
Ibuprofen (Advil, Motrin)
- Mechanisms
- NSAID
- COX Inhibitor
- Indications
- General Pain
- Fever
- Inflammatory Conditions
- Side Effects
- GI Ulcers
- Nephrotoxicity
- Rash
- Considerations
- Avoid with Alcohol
- Risk of Thrombotic Event
2 mins
Prednisone (Glucocorticoids)
- Mechanism
- Glucocorticoid
- Indications
- Inflammatory Conditions
- Organ Transplant Rejection
- Side Effects
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Considerations
- Adrenal Insufficiency
- Taper Gradually
2 mins
Acetaminophen
- Indications
- Fever
- Pain
- Mechanism of Action
- Reversibly Inhibits COX
- Acts Primarily in CNS
- Side Effect
- Hepatic Necrosis
- N-acetylcysteine Antidote
51 secs
Acetaminophen Antidote
- Antidote
- N-Acetylcysteine
33 secs
Celecoxib
- Indications
- Rheumatoid Arthritis
- Osteoarthritis
- Pain
- Mechanism of Action
- NSAID
- Selectively Inhibits COX-2
- Side Effects
- Sulfa Allergy
- Increased Risk of Thrombosis
- GI Bleed
- Contraindication
- Pregnancy > 30 Weeks
1 min
Alendronate (Fosamax)
- Mechanism
- Inhibits Osteoclasts
- Indications
- Osteoporosis
- Paget's Disease
- Side Effects
- Esophageal Ulcers
- Musculoskeletal Pain
- Vision Changes
- Atrial Fibrillation
- Osteonecrosis of the Jaw
- Considerations
- Take on Empty Stomach
- Remain Upright
2 mins
TNF-Alpha Inhibitors Overview
- Mechanism
- Downregulates Pro-inflammatory Cytokines
- Decreased Lymphocyte Activation and Migration
- Granuloma Breakdown
- Treats
- Crohn's Disease
- Rheumatoid Arthritis
- Juvenile Rheumatoid Arthritis
- Psoriasis
- Ankylosing Spondylitis
1 min
TNF-Alpha Inhibitor Drugs and Complications
- Etanercept
- Decoy TNF- Alpha receptor
- Anti-TNF- Alpha antibody
- Adalimumab
- Infliximab
- Complications
- Increased risk of infection
- Predispose to Tuberculosis (TB) reactivation
- Order Baseline PPD- skin test
- Quantiferon Gold In-Tube
- Order Chest X-Ray
2 mins
Anticholinergics
- B.O.AT.S Acronym
- Benztropine
- Parkinson's Disease
- Oxybutynin
- Decrease bladder spasms
- Atropine
- Mydriasis and Cycloplegia
- Scopolamine
- Motion Sickness
1 min
Anticholinergics Continued
- Drugs
- Glycopyrrolate
- Reduces Airway Secretions
- Ulcer Treatment
- Ipratropium
- Asthma and C.O.P.D
- Dicyclomine
- Hyoscyamine
- Irritable Bowel Syndrome
1 min
Atropine
- Indications
- Blocks DUMBBeLSS
- Bradycardia
- Side Effects
- Skin Flushing
- Increased Temperature
- Dry Mouth
- Cycloplegia
- Disorientation
- Mydriasis
1 min
Benztropine (Cogentin)
- Mechanism
- Anticholinergic
- Indications
- Parkinson's Disease
- Acute Dystonia
- Side Effects
- Blurred Vision
- Dry Mouth
- Urinary Retention
- Tachycardia
- Constipation
- Psychosis
2 mins
Direct Cholinomimetics
- Muscarinic Agonists
- Bethanechol
- Bladder and Bowels
- Methacholine
- Bronchoconstriction
- Pilocarpine
- Contracts Ciliary Muscle and Pupillary Sphincter
- Carbachol
- Releases Intraocular Pressure
1 min
Indirect Cholinomimetics
- Acetylcholinesterase Inhibitors
- Doesn't Cross BBB
- Edrophonium
- Myasthenia Gravis (Diagnosis)
- Pyridostigmine and Neostigmine
- Myasthenia Gravis (Tx)
- Ileus
- Crosses BBB
- Physostigmine
- Atropine Overdose
- Glaucoma
- Donepezil
- Alzheimer's
2 mins
Pilocarpine (Pilocar)
- Mechanism
- Direct Cholinergic Agonist
- Contracts Iris Sphincter
- Contracts Ciliary Muscle
- Indications
- Xerostomia
- Glaucoma
- Side Effects
- Detached Retina
- Decreased Visual Acuity
- Eye Irritation
- Cholinergic Effects
- Considerations
- Avoid with Asthma or Bradycardia
2 mins
Acetylcholinesterase Inhibitor Antidote
- Antidote
- Atropine
- Pralidoxime
1 min
