Hillary Shared "Pharm Exam 2" - 41 Picmonics
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Pharm Exam 2
Warfarin
- Mechanism of Action
- Interferes with Vitamin K-dependent Clotting Factors
- Extrinsic Pathway
- Bridge with Heparin
- Indications
- Chronic Anticoagulation
- Side Effects
- Bleeding
- Necrosis
- Cytochrome P450
- Contraindications
- Pregnancy
- Antidote
- FFP + Vitamin K
2 mins
Clopidogrel (Plavix)
- Mechanism
- ADP Receptor Antagonist
- Prevent Platelet Aggregation
- Indications
- Acute Coronary Syndrome (ACS)
- Prevention of Thrombotic Events
- Side Effects
- Bleeding
- Thrombotic Thrombocytopenic Purpura (TTP)
- Pancytopenia
- Abdominal Pain
- Considerations
- Withhold Before Surgery
2 mins
Autonomic Nervous System
- Characteristics
- Sympathetic Nervous System
- Fight or Flight
- All Preganglionic Neurons Release Acetylcholine
- Sympathetic Postganglionic Neurons Release Norepinephrine
- Antagonistic Effects of Sympathetic and Parasympathetic Nervous Systems
- Parasympathetic Nervous System
- Rest and Digest
- Parasympathetic Postganglionic Neurons Release Acetylcholine
2 mins
Atropine
- Indications
- Blocks DUMBBeLSS
- Bradycardia
- Side Effects
- Skin Flushing
- Increased Temperature
- Dry Mouth
- Cycloplegia
- Disorientation
- Mydriasis
1 min
Anticholinergics
- B.O.AT.S Acronym
- Benztropine
- Parkinson's Disease
- Oxybutynin
- Decrease bladder spasms
- Atropine
- Mydriasis and Cycloplegia
- Scopolamine
- Motion Sickness
1 min
Anticholinergics Continued
- Drugs
- Glycopyrrolate
- Reduces Airway Secretions
- Ulcer Treatment
- Ipratropium
- Asthma and C.O.P.D
- Dicyclomine
- Hyoscyamine
- Irritable Bowel Syndrome
1 min
Direct Cholinomimetics
- Muscarinic Agonists
- Bethanechol
- Bladder and Bowels
- Methacholine
- Bronchoconstriction
- Pilocarpine
- Contracts Ciliary Muscle and Pupillary Sphincter
- Carbachol
- Releases Intraocular Pressure
1 min
Benztropine (Cogentin)
- Mechanism
- Anticholinergic
- Indications
- Parkinson's Disease
- Acute Dystonia
- Side Effects
- Mydriasis
- Dry Mouth
- Urinary Retention
- Tachycardia
- Constipation
- Psychosis
1 min
Antimuscarinic Antidote
- Antidote
- Physostigmine Salicylate
44 secs
Acetylcholinesterase Inhibitor Antidote
- Antidote
- Atropine
- Pralidoxime
1 min
Acetylcholinesterase Inhibitor Poisoning
- DUMBBELSS
- Diarrhea
- Urination
- Miosis
- Bronchospasm
- Bradycardia
- Emesis
- Lacrimation
- Salivation
- Sweating
2 mins
Indirect Cholinomimetics
- Acetylcholinesterase Inhibitors
- Doesn't Cross BBB
- Edrophonium
- Myasthenia Gravis (Diagnosis)
- Pyridostigmine and Neostigmine
- Myasthenia Gravis (Tx)
- Ileus
- Crosses BBB
- Physostigmine
- Atropine Overdose
- Glaucoma
- Donepezil
- Alzheimer's
2 mins
Donepezil
- Indications
- Alzheimer's Disease
- Mechanism of Action
- Acetylcholinesterase Inhibitor
- Increased Acetylcholine
- Side Effects
- Nausea and Vomiting
- Dizziness
52 secs
Succinylcholine
- Indications
- Inducing Paralysis
- Mechanism of Action
- Neuromuscular Blocking Drugs
- Motor Nicotinic Receptor
- ACh Receptor Agonist
- Depolarization
- Phases of Action
- Phase I (Paralysis Non-reversible)
- Phase II (Paralysis Reversible)
- Neostigmine (Reversal Agent)
2 mins
Nondepolarizing Neuromuscular Blocking Drugs
- Names Include "Cur"
- Competitive Antagonists
- Acetylcholine Competition
- Reversal of Blockade
- Neostigmine, Edrophonium
1 min
Myasthenia Gravis
- Mechanism
- Antibodies to Acetylcholine Receptor
- Symptoms
- Ptosis
- Diplopia
- Weakness with Muscle Use
- Respiratory Death
- Thymus Associated
- Treatment
- Acetylcholinesterase Inhibitors
- Plasmapheresis
- Thymectomy
1 min
Promethazine (Phenergan)
- Mechanism
- Histamine H1 Receptor Antagonist
- Weak Dopamine Antagonist
- Indications
- Nausea and Vomiting
- Motion Sickness
- Side Effects
- Respiratory Depression
- Sedation
- Anticholinergic Effects
- Extrapyramidal Symptoms
- Considerations
- Use Large Bore IV
- Monitor for Tissue Necrosis
2 mins
Hypersensitivity Type I
- Previous Antigen Exposure
- Immediate Reaction
- IgE Cross-linking
- Presensitized Mast Cells
- Histamine Release
- Vasodilation
- Anaphylaxis
- Allergies
- Treatment
- Epinephrine
1 min
Anaphylaxis Intervention
- Intervention
- Assess Airway and Oxygen Needs
- Reassure Patient with Anxiety
- Supine Position
- Methylprednisolone (Solu-medrol)
- Epinephrine
- Diphenhydramine (Benadryl)
- Medical Alert Bracelet
2 mins
H2 Receptor Blocker
- "-tidine" Suffix
- Indications
- Gastroesophageal Reflux Disease (GERD)
- Peptic Ulcer
- Mechanism
- Block Histamine H2 Receptors
- Parietal Cells
52 secs
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