Adam Shared "Peds 2" - 20 Picmonics
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Peds 2
Tuberous Sclerosis
- Characteristics
- Autosomal Dominant
- Signs and Symptoms
- Hamartomas in CNS and Skin
- Phakoma
- Subependymal Giant Cell Astrocytoma
- Seizures
- Intellectual Disability (Mental Retardation)
- Adenoma Sebaceum
- Shagreen Patch
- Ash-leaf Spots
- Renal Angiomyolipoma
- Cardiac Rhabdomyoma
2 mins
Muscular Dystrophy
- Mechanism
- X-linked Recessive
- Signs and Symptoms
- Muscle Weakness
- Motor Problems
- Gower Sign
- Large Calves
- Waddling Gait
- Loss of Ambulation
- Consideration
- Cardiac and Respiratory Failure
2 mins
Friedreich's Ataxia
- Trinucleotide Repeat
- GAA Repeat
- Frataxin
- Mitochondrial Dysfunction
- Autosomal Recessive
- Hammertoes
- High Arches
- Kyphoscoliosis
- Lateral Corticospinal Tract
- Posterior Column
- Spinocerebellar Tract
- Type I Diabetes Mellitus
- Hypertrophic Cardiomyopathy
1 min
Marfan Syndrome
- Mechanism
- Fibrillin-1 Mutation
- Symptoms
- Autosomal Dominant
- Tall
- Arachnodactyly
- Pectus Excavatum
- Hypermobile Joints
- Aortic Aneurysm And Dissection
- Mitral Valve Prolapse (MVP)
- Subluxation of Lens (Superior)
2 mins
Ehlers-Danlos Syndrome Types
- Types
- Types 1 and 2 - Classical
- Type V Collagen Mutation
- Joints and Skin
- Type 3 - Hypermobility
- Most Common
- Tenascin X Deficiency
- Joint Instability
- Type 4 - Vascular
- Type III Collagen Mutation
- Vascular and Organ Rupture
2 mins
Ehlers-Danlos Syndrome Disease
- Pathophysiology
- Faulty Collagen Synthesis
- Autosomal Dominant or Recessive
- Various Severities
- Signs and Symptoms
- Hypermobile Joints
- Hyperextensible Skin
- Easy Bruising/Bleeding
- Berry (Saccular) Aneurysm
- Considerations
- Brighton Criteria
2 mins
Acute Lymphoblastic Leukemia (ALL)
- Ages < 15
- May Present with Bone Marrow Involvement in Children
- Mediastinal Mass in Adolescents
- TdT Positive
- CALLA Positive
- t(12;21) Better Prognosis
- Spread to CNS and Testes
- Most Responsive to Chemotherapy
2 mins
Chronic Myelogenous Leukemia (CML)
- Pathophysiology
- BCR-ABL
- 9;22 Translocation
- Philadelphia Chromosome
- Signs & Symptoms
- Tyrosine Kinase
- Low Alkaline Phosphatase
- Splenomegaly
- Considerations
- Blast Crisis
- Age 30 to 90 Years
- Responds to Imatinib
3 mins
Acute Myelogenous Leukemia (AML)
- Myeloblasts Increase on Peripheral Smear
- Median Onset 60 Years
- T 15;17 M3 Subtype
- Auer Rods
- Disseminated Intravascular Coagulation (DIC) is a Common Presentation
- M5 Gum Infiltration
- Responds to Vitamin A
3 mins
Wilms' Tumor (Nephroblastoma)
- Cause
- Malignant Renal Tumor
- Assessment
- Abdominal Mass
- Hematuria
- Fever
- Hypertension
- Interventions
- Nephrectomy
- Chemotherapy
- Radiation
- Considerations
- Do Not Palpate Abdomen
- Children Under 5 Years Old
2 mins
Ewing's Sarcoma
- Epidemiology
- Most Common in Boys < 15 years old
- Pathophysiology
- 11;22 Translocation
- Characteristics
- Long bones, Pelvis, Ribs
- Diaphysis
- Small Blue Cells
- Malignant
- Aggressive
- Onion-skin Appearance
- TREATMENT
- Responsive to Chemotherapy
2 mins
Osteosarcoma
- Pathophysiology
- Osteogenic Sarcoma
- Peak incidence men 10-20 years old
- Metaphysis of Long Bones
- Knee Region
- Radiation
- Familial Retinoblastoma
- Paget's Disease
- Diagnosis
- Codman Triangle
- Sunburst Pattern from Elevated Periosteum
- Grave Prognosis
2 mins
Chronic Lymphocytic Leukemia (CLL)
- Signs and Symptoms
- Age > 60 Years
- B Cell Neoplasm
- Smudge Cells
- Often Asymptomatic
- Cold IgM Autoimmune Hemolytic Anemia
- Warm IgG Autoimmune Hemolytic Anemia
- Richter's Transformation
3 mins
Tetralogy of Fallot (TOF)
- Features
- Blue Baby Syndrome
- Mechanism
- PROVe Acronym
- Pulmonary Infundibular Stenosis
- Right Ventricular Hypertrophy
- Overriding Aorta
- Ventricular Septal Defect (VSD)
- Diagnosis and Treatment
- Boot-Shaped Heart
- Squatting for Tet Spells
- Surgery
2 mins
Total Anomalous Pulmonary Venous Return (TAPVR)
- Pathophysiology
- Pulmonary Veins Do Not Connect to Left Atrium
- Oxygenated Blood Return to Right Atrium
- Incompatible with Life without a Shunt
- With Obstruction
- Vessel Enters at an Acute Angle
- Severe Cyanosis
- Pulmonary Edema
- Without Obstruction
- Delayed Manifestation (1 or 2 years)
- Right Heart Failure
- Chest X-ray Shows "Snowman"
- Diagnosis
- Echocardiogram
- Treatment
- Surgical Correction
3 mins
Transposition of Great Vessels
- Pathophysiology
- Pulmonary and Systemic Circulation are in Parallel
- Incompatible with Life Without a Shunt
- Symptoms
- Severe Cyanosis at Birth
- Single S2 sound
- Diagnosis
- Echocardiogram
- Chest X-ray shows "Egg-shaped Silhouette"
- Treatment
- Prostaglandin
- Avoid NSAIDs
- Surgical Correction
- Balloon Atrial Septostomy
2 mins
Persistent Truncus Arteriosus
- Common Arterial Trunk
- Single Trunk Emerges from Both Ventricles
- Symptoms
- Cyanosis
- Pulmonary Congestion
- Heart Failure
- Single S2 Sound
- Diagnosis
- Echocardiogram
- Chest X-ray
- Treatment
- Early Surgical Correction
- Avoids Pulmonary Hypertension
2 mins
Osteogenesis Imperfecta
- Pathophysiology
- Autosomal Dominant
- Decreased Type I Collagen Production
- Symptoms
- Phenotypically Diverse
- Brittle Bone Disease
- Fractures from Minimal Trauma
- Confused with Child Abuse
- Hearing Loss
- Dental Imperfections
- Blue Sclera
1 min
Legg-Calve-Perthes Disease
- Pathophysiology
- Idiopathic Avascular Necrosis of Femoral Head
- Boys 5-7 Years of Age
- Symptoms < 18 Months
- Signs & Symptoms
- Painless Limp
- Limited Range of Motion
- Intermittent Anterior Thigh Pain
- Insidious Pain in Knee
- Atrophy of Upper Thigh
- Diagnosis
- AP and Frog Leg Lateral X-ray
- Compression and Deformity of Femoral Head
- Treatment
- Bed Rest
- NSAIDs
- Containment with Brace or Cast
- Surgery
4 mins
Slipped Capital Femoral Epiphysis (SCFE)
- Pathophysiology
- Separation of Femoral Epiphysis from Femoral Neck
- Through Growth Plate (Physeal Plate)
- Obesity
- Male Adolescents
- African American
- Growth and Sex Hormone Imbalances
- Signs & Symptoms
- Thigh or Knee Pain
- Inability to Bear Weight
- Decreased Internal Rotation of Hip
- Obligate External Rotation of Hip with Flexion
- Diagnosis
- Frog Leg Lateral X-ray
- Treatment
- Surgical Pinning
- Complications
- Avascular Necrosis of Femoral Head
3 mins
