Amanda Shared "Labor and Delivery Drugs" - 11 Picmonics
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Labor and Delivery Drugs
Magnesium Sulfate
Mechanism
Muscle Relaxant
Indications
Preterm Labor Contractions
Preeclampsia
Side Effects
Warm Feeling
Hypotension
Decreased Deep Tendon Reflexes (DTRS)
Decreased Respiratory Rate
Decreased Urine Output
Paralytic Ileus
Antidote
Calcium Gluconate
2 mins
Oxytocin (Pitocin)
Mechanism of Action
Increase Uterine Contractions
Indications
Labor Induction
Control Postpartum Hemorrhage
Side Effects
Uterine Rupture
Water Intoxication
Contraindications
Fetal Lung Immaturity
Cervix Not Ripened
Active Genital Herpes Infection
Considerations
Use Lowest Dose
IV Pump
3 mins
Dinoprostone and Misoprostol
Mechanism
Mechanism
Prostaglandins
Prostaglandins
Indications
Indications
Promote Cervical Ripening
Promote Cervical Ripening
Prevent GI Ulcers
Prevent GI Ulcers
Medical Abortion
Medical Abortion
Side Effects
Side Effects
Fetal Distress
Fetal Distress
Hyperstimulation of Uterus
Hyperstimulation of Uterus
Considerations
Considerations
Vaginal Insertion
Vaginal Insertion
Give Before Induction of Labor
Give Before Induction of Labor
2 mins
Methylergonovine (Methergine) and Ergotamine (Ergot Alkaloids)
Mechanism
Smooth Muscle Contraction
Vasoconstriction
Indications
Migraine
Postpartum Hemorrhage
Side Effects
Nausea and Vomiting
Severe Hypertension
Tachycardia
Considerations
2nd Line Agent
2 mins
Carboprost (Hemabate)
Mechanism
Prostaglandin F2-alpha Analog
Smooth Muscle Contraction
Indications
Postpartum Hemorrhage
Abortion
Side Effects
GI Distress
Hypertension
Fever
Bronchoconstriction
Considerations
Identify Cause of Fever
2 mins
Butorphanol
Indications
Migraine
Severe Pain
Labor
Mechanism of Action
Partial Agonist at Mu and Full Agonist at Kappa Receptors
Less Respiratory Depression
Side Effects
Withdrawal Symptoms
1 min
Hydralazine (Apresoline)
Indications
Severe Hypertension
CHF
Reduced Afterload
Pregnancy
Mechanism of Action
Vasodilates Arterioles
Side Effects
Drug-induced Lupus
Reflex Tachycardia
Hypotension
Considerations
Combined with Diuretic and Beta Blocker
1 min
Terbutaline (Brethine)
Mechanism of Action
Mechanism of Action
Beta-2 Agonists
Beta-2 Agonists
Indications
Indications
Asthma
Asthma
Tocolytic
Tocolytic
Side Effects
Side Effects
Hypotension
Hypotension
Tremor
Tremor
Tachycardia
Tachycardia
Pulmonary Edema
Pulmonary Edema
Hyperglycemia
Hyperglycemia
2 mins
Meperidine (Demerol)
Mechanism
Mechanism
Opioid Receptor Agonist
Opioid Receptor Agonist
Indications
Indications
Moderate to Severe Pain
Moderate to Severe Pain
Post Anesthesia Shivering
Post Anesthesia Shivering
Side Effects
Side Effects
Tremors
Tremors
Constipation
Constipation
CNS Depression
CNS Depression
Sedation
Sedation
Considerations
Considerations
Short Term Administration
Short Term Administration
Increased Risk Serotonin Syndrome
Increased Risk Serotonin Syndrome
Does NOT cause Miosis
Does NOT cause Miosis
Renal Failure Increases Toxicity Risk
Renal Failure Increases Toxicity Risk
2 mins
Promethazine (Phenergan)
Mechanism
Histamine H1 Receptor Antagonist
Weak Dopamine Antagonist
Indications
Nausea and Vomiting
Motion Sickness
Side Effects
Respiratory Depression
Sedation
Anticholinergic Effects
Extrapyramidal Symptoms
Considerations
Use Large Bore IV
Monitor for Tissue Necrosis
2 mins
Naloxone (Narcan)
Mechanism
Competitive Opioid Receptor Antagonist
Indications
Opioid Induced CNS Depression
Side Effects
Severe Nausea and Vomiting
Excitable State
Opioid Withdrawal Symptoms
Considerations
Repeated Dosing Often Required
1 min
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