MackenzieCooke073494 Shared "Micro Exam 3" - 33 Picmonics
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Micro Exam 3
Blastomyces
- Characteristics
- Fungi
- Hyphae Form at 20°-25°C
- Yeast Form at 37°C
- Round Yeast
- 5-15 Micrometer (um or μm)
- Single Broad-Based Buds
- Thick Doubly-Refractive Walls
- East of the Mississippi River and Around the Great Lakes
- Signs and Symptoms
- Pneumonia
- Skin Infection
- Bone Infection
- Granulomatous Response
- Treatment
- Itraconazole
- Amphotericin B
3 mins
Histoplasmosis
- Fungi
- 2-5 um
- Yeast Cells within Macrophages
- Starling Bird Poop
- Bat Poop
- Caves
- Mississippi and Ohio River Valleys
- Pneumonia
- Caseating Granuloma
- Erythema Nodosum
1 min
Coccidioidomycosis
- Characteristics
- Fungi
- Dimorphic
- Southwest
- After earthquakes
- Spherule
- 20-60 um
- Signs and Symptoms
- Pneumonia
- Meningitis
- Bone Infection
- Skin infections
- Erythema Nodosum
- Granulomatous Inflammation
- Caseous Necrosis
2 mins
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
Amphotericin B
- Indications
- Systemic Mycosis
- Fungal Meningitis
- Last Resort for Protozoan infections
- Mechanism
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
1 min
Flucytosine
- Indications
- Cryptococcus
- Candida
- Used in Combination with Amphotericin B or Azoles
- Mechanism
- Inhibits DNA and RNA Synthesis
- Converted to 5-FU by Cytosine Deaminase
- Side Effects
- Bone Marrow Suppression
1 min
Terbinafine
- Indications
- Dermatophytosis
- Onychomycosis
- Mechanism
- Inhibits Squalene Epoxidase
- Side Effects
- Hepatotoxicity
- GI Distress
- Taste Disturbances
- Headache
2 mins
Echinocandins
- "-Fungin" Suffix
- Indications
- Invasive Aspergillosis
- Candida
- Mechanism
- Inhibits Cell Wall Synthesis
- Inhibits Synthesis of Beta-glucan
- Side Effects
- GI Distress
- Flushing
1 min
Aspergillus fumigatus
- Characteristics
- Fungi
- Monomorphic
- Septate Hyphae
- Branch at Acute Angles
- Fruiting Bodies
- Disease
- Allergic Bronchopulmonary Aspergillosis (ABPA)
- Eosinophilia
- Increased IgE
- Glucocorticoids +/- Azoles
- Pulmonary Aspergillosis
- TB Cavity
- Lung Aspergilloma
- Hemoptysis
- Invasive Aspergillosis
- AIDS/Immunocompromised
- Chronic Granulomatous Disease
- Hemorrhagic Infarction
- Necrotizing Bronchopneumonia
- Voriconazole +/- Caspofungin
3 mins
Candida Albicans
- Fungi
- Yeast with Pseudohyphae at 20 Degrees C
- Germ Tube Formation at 37 Degrees C
- Pruritic Vaginitis
- White Cottage Cheese Discharge
- Fiery Red Mucosa
- Diabetics
- Antibiotic Use
- Esophageal Thrush in Immunocompromised
- Diaper Rash
- Endocarditis in IV Drug Users
2 mins
Cryptococcus neoformans
- Characteristics
- Monomorphic
- Encapsulated
- Polysaccharide Capsule
- Narrow-Based Buds
- Latex Agglutination
- Pigeons
- India Ink
- Mucicarmine stain
- Signs and Symptoms
- AIDS/Immunocompromised
- Meningitis
- Soap Bubble Lesions in Brain
- Pneumonia
- Treatment
- Fluconazole
- Flucytosine
- Amphotericin
3 mins
Pneumocystis jirovecii
- Fungi
- AIDS/Immunocompromised
- Fever
- Hypoxemia
- Bronchoalveolar Lavage
- Biopsy
- Methenamine Silver Stain
- Saucer/cup shaped yeast forms
- Diffuse interstitial pneumonia CXR
- TMP-SMX
- Start prophylaxis when CD4 drops under 200
1 min
Sporothrix Schenckii
- Characteristics
- Fungi
- Thermally Dimorphic
- Cigar-shaped Yeast Forms
- Rose Thorn Prick
- Packaging Peat Moss
- Signs & Symptoms
- Local Pustule or Ulcer
- Nodules on Draining Lymphatics
- Treatment
- Potassium Iodide
- Itraconazole
2 mins
Plasmodium General
- Characteristics
- Protozoa
- Malaria
- Anopheles Mosquito
- Signs and Symptoms
- Cyclic Fever
- Headache
- Anemia
- Splenomegaly
- Diagnosis
- Blood Smear
- Treatment
- Chloroquine
- Mefloquine for Resistant Types
3 mins
Plasmodium Specific
- Malariae
- Fever Every Three Days
- Vivax/Ovale
- Fever Every Two Days
- Duffy Antigen Binding Site
- Duffy often absent in Black Population
- Primaquine treats dormant form in liver
- Falciparum
- Most severe
- Irregular Cycles
- Occludes capillaries in the brain, kidneys, and lungs
4 mins
Babesia
- Characteristics
- Protozoa
- Ixodes Tick
- Same vector as Borrelia
- Northeastern US
- Asplenia
- Signs and Symptoms
- Fever
- Hemolytic Anemia
- Diagnosis
- Blood Smear
- Maltese Cross
- Treatments
- Atovaquone
- Azithromycin
3 mins
Toxoplasma gondii
- Characteristics
- Protozoa
- Cysts in Meat or Cat Feces
- Signs and Symptoms
- Brain Abscess in HIV Patients
- Ring-enhancing Brain Lesions
- Crosses Placenta in Pregnant Women
- Congenital TORCH Infection
- Treatment
- Pyrimethamine
- Sulfadiazine
2 mins
Leishmania donovani
- Pathophysiology
- Protozoan
- Visceral Leishmaniasis
- Hepatosplenomegaly
- Spiking Fevers
- Skin Pigmentation
- Sandfly
- Diagnosis
- Macrophages with Amastigotes
- Treatment
- Amphotericin B
- Oral Miltefosine
2 mins
Trypanosoma cruzi
- Pathophysiology
- Protozoa
- Triatomine Bug
- Kissing bug
- Painless bite
- Predominantly in South America
- Symptoms
- Chagas disease
- Romana's sign
- Dilated Cardiomyopathy
- Megacolon
- Megaesophagus
- Diagnosis
- Blood smear
- Treatment
- Nifurtimox
- Benznidazole
2 mins
Naegleria Fowleri
- Pathophysiology
- Protozoa
- Rapidly Fatal Meningoencephalitis
- Swimming in Freshwater Lakes
- Travels Through Cribriform Plate
- Diagnosis
- Amoebas in CSF
- Treatment
- Amphotericin B
- Death is Still Common
1 min
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