Katherine Shared "MICROBIOLOGY" - 123 Picmonics
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MICROBIOLOGY
HIV Prophylaxis Medications
- CD4+ < 200
- TMP-SMX
- Pneumocystis Pneumonia
- CD4+ < 100 Susceptible to Toxoplasma Gondii
- CD4+ < 50
- Mycobacterium Avium and Intracellulare
- Azithromycin If Delayed Therapy
2 mins
HIV CD4+ 500
- Signs and Symptoms
- Candida albicans (Oral Thrush)
- Kaposi's Sarcoma (HHV-8)
- Human Papillomavirus (HPV)
- Epstein-Barr Virus (Oral Hairy Leukoplakia)
3 mins
HIV CD4+ 200
- Signs and Symptoms
- Herpes Simplex Virus (HSV)
- JC Virus
- Progressive Multifocal Leukoencephalopathy (PML)
- Pneumocystis Pneumonia
- (HIV) Dementia
- Histoplasmosis
3 mins
HIV CD4+ 100
- Signs and Symptoms
- Aspergillus fumigatus
- Cryptococcus neoformans
- Candida albicans (Esophagitis)
- Mycobacterium avium complex (MAC)
- Cytomegalovirus (CMV)
- Epstein-Barr virus (EBV) B-cell lymphoma
- Toxoplasma gondii
- Cryptosporidium
- Bartonella henselae
5 mins
Human Immunodeficiency Virus (HIV) Interventions
- Interventions
- Adequate Nutrition
- Small Frequent Meals
- IV Hydration
- Emotional Support
- HIV Medications
- HAART
- Considerations
- Transmission Education
- Strict Asepsis for Invasive Procedures
- Treat Opportunistic Infections
2 mins
Human Immunodeficiency Virus (HIV) Diagnosis
- HIV-1/2 Antigen/Antibody Immunoassay
- HIV-1/2 Antibody Differentiation Immunoassay
- Nucleic Acid Testing (NAT)
- Viral Load
- Polymerase Chain Reaction (PCR) in Neonates
3 mins
Human Immunodeficiency Virus (HIV) Assessment
- Assessment
- RNA Retrovirus
- CD4+ Helper T Cells
- Primary Infection
- Flu-like Symptoms
- Lymphadenopathy
- Symptomatic Stage
- Fatigue
- Diarrhea
- Unexplained Weight Loss
- White Spots on Tongue
- Persistent Fever
- Night Sweats
2 mins
Human Immunodeficiency Virus (HIV) Stages
- Primary Infection
- Within 3 Weeks
- Flu-like Symptoms
- Asymptomatic Stage
- Years
- Symptomatic Stage
- CD4+ < 500
- AIDS
- Opportunistic Infections
- CD4+ < 200
2 mins
Fusion Inhibitors
- Indications
- HIV
- Drugs
- Maraviroc
- Binds CCR-5 on T Cells
- Blocks Interaction with gp120
- Enfuvirtide
- Binds gp41
- Inhibits Viral Entry
- Side Effects
- Skin Reactions at Injection Sites (Enfuvirtide)
2 mins
HAART
- HIV
- Begin at Diagnosis
- 3 Drugs
- 2 NRTIs (Nucleoside Reverse Transcriptase Inhibitors)
- And one of the following:
- NNRTI (Non-Nucleoside Reverse Transcriptase Inhibitor)
- or Protease Inhibitor
- or Integrase Inhibitor
1 min
NRTIs (Nucleoside Reverse Transcriptase Inhibitors)
- Indications
- HIV
- Pregnancy and Prophylaxis given ZDV
- Mechanism
- Inhibit Nucleotide Binding to Reverse Transcriptase
- Chain Termination
- Require Phosphorylation
1 min
Focal Segmental Glomerulosclerosis
- Most Common Cause of Nephrotic Syndrome in Hispanic People and African Americans
- Associated with Sickle Cell Disease and HIV
- Associated Interferon Therapy and Heroin Abuse
- Histopathology
- LM Segmental Sclerosis and Hyalinosis
- EM Focal Damage of Visceral Epithelial Cells
- IF Negative
- Signs & Symptoms
- Microscopic Hematuria
- Nonselective Proteinuria
- Considerations
- Poor Prognosis
2 mins
Protease Inhibitors
- End in "-navir"
- Indications
- HIV/AIDS
- Hepatitis C
- Mechanism
- Inhibit Protease
- Unable to Cleave Proteins
- Inhibits Maturation of New Virus
- Side Effects
- GI Distress
- Nephropathy
- Lipodystrophy
- Hyperglycemia
3 mins
Integrase Inhibitors
- -gravir Suffix
- Indications
- HIV
- Mechanism
- Blocks Insertion of Viral Genome
- Inhibit Actions of Integrase
- Side Effects
- Hypercholesterolemia
- Increased LFT's
- Insomnia
- Increased Creatine Kinase (CK)
1 min
Bacteroides Fragilis
- Characteristics
- Gram-Negative
- Anaerobe
- Normal Colonic Flora
- Produces Vitamin K
- Produces Gas in Tissue
- Foul-Smelling
- Signs and Symptoms
- Gastrointestinal Abscess
- Treatment
- Penicillin-Resistant
- Clindamycin
- Metronidazole
2 mins
Bordetella pertussis
- Pathophysiology
- Gram-Negative
- Coccobacillus
- Bordet-Gengou Agar
- ADP Ribosylating AB Toxin
- Inhibits Gi to cause Increase in cAMP
- Signs AND Symptoms
- Lymphocytosis
- Increase in Insulin
- Catarrhal Phase is Infectious Period
- Paroxysmal Phase is Symptomatic Period
- Whooping Cough
- Treatment
- Macrolides
4 mins
Staphylococcus aureus Disease
- Skin Infections
- Impetigo
- Abscesses
- Exfoliative Toxin
- Scalded Skin Syndrome
- Toxic Shock Syndrome (TSST 1)
- Binds to MHC II and T Cell Receptor
- Food Poisoning
- Acute Bacterial Endocarditis
- Pneumonia
- Osteomyelitis
2 mins
Staphylococcus saprophyticus
- Characteristics
- Gram-Positive
- Cocci
- Catalase-Positive
- Coagulase-Negative
- Novobiocin-Resistant
- Urease-Positive
- Disease
- Urinary Tract Infections (UTI's)
1 min
Staphylococcus aureus Characteristics
- Characteristics
- Gram-Positive
- Cocci
- Catalase-Positive
- Coagulase-Positive
- Beta-Hemolytic
- Protein A Virulence Factor
- Inhibits Phagocytosis
- MRSA
- Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
2 mins
Staphylococcus epidermidis
- Characteristics
- Cocci
- Gram-Positive
- Catalase-Positive
- Urease-Positive
- Coagulase-Negative
- Novobiocin-Sensitive
- Component of Normal Skin Flora
- Infects Prosthetic Devices and IV Catheters
- Contaminates Blood Cultures
- Produces Adherent Biofilms
2 mins
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