OnlineMedEd Shared "General Pharmacology - Adrenergics (SNS)" - 8 Picmonics
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General Pharmacology - Adrenergics (SNS)
Alpha 1 Receptor
- Characteristics
- Gq Subunit
- Increase Vascular Smooth Muscle Contraction
- Increase Pupillary Dilator Muscle Contraction
- Increase Intestinal and Bladder Sphincter Muscle Contraction
1 min
Alpha 2 Receptor
- Characteristics
- Gi Subunit
- Decrease Sympathetic Outflow
- Decrease Insulin Release
- Decrease Lipolysis
- Increase Platelet Aggregation
- Decrease Aqueous Humor Production
2 mins
Beta-1 Receptor
- Characteristics
- Gs Protein Class
- Increased Heart Rate
- Increased Contractility
- Increase Renin Release
- Increased Lipolysis
44 secs
Beta-2 Receptor
- Characteristics
- Gs protein class
- Increased Heart Rate
- Increased Contractility
- Increased Lipolysis
- Increased Insulin
- Increased Aqueous Humor Production
- Ciliary Muscle Relaxation
- Vasodilation
- Bronchodilation
- Decrease Uterine Tone
2 mins
Cardiovascular Effects of Beta-Blockers
- Cardiac Myocytes and Vasculature
- Decrease cAMP
- Decreases SA and AV Node Conduction Velocity
- Lower Blood Pressure
- Decrease O2 Consumption
- Decreases Mortality Post-MI
2 mins
Selective Alpha-1 Blockers
- "-osin" suffix
- Mechanism of Action
- Blocks Alpha1 Receptors
- Indications
- Hypertension
- Benign Prostatic Hyperplasia (BPH)
- Side Effects
- Syncope
- Orthostatic Hypotension
1 min
Selective Alpha-2 Blockers
- Mirtazapine
- Indications
- Depression Treatment
- Mechanism of Action
- Blocks Alpha2 Receptor
- Antagonist at 5-HT receptors
- Side Effects
- Sedation
- Weight gain
- Increased Serum Cholesterol
1 min
Closed-Angle Glaucoma
- Primary
- Lens causes pupillary obstruction
- Aqueous humor builds behind iris
- Iris bends forward, obstructing trabecular mesh
- Secondary
- Hypoxia Causes Neovascular Proliferation
- Contraction and obstruction of trabecular mesh
- Chronic disease (Crone)
- Asymptomatic
- Acute Disease
- Eye pain and blindness
- Rock-hard eye
- Headache
- Emergency
- Epinephrine contraindicated
2 mins
