Andrew Shared "S1 DMSK Week 4" - 83 Picmonics
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S1 DMSK Week 4
Multiple Myeloma Pathophysiology
- Pathophysiology
- Monoclonal Plasma Cell Cancer
- Clock Face Chromatin
- Diagnosis
- M Spike on Protein Electrophoresis
- Increased IgG and IgA
- Fried Egg Appearance (BM Biopsy)
- Rouleaux Formation
- Stacked RBC's
- Bence Jones Protein
2 mins
Multiple Myeloma Signs and Symptoms
- Signs and Symptoms
- Increased Susceptibility to Infection
- Back/Bone Pain
- Punched Out Lytic Bone Lesions
- Hypercalcemia
- Primary Amyloidosis
- Renal Insufficiency
- Anemia
2 mins
Giant Cell Tumor
- Pathophysiology
- Osteoclastoma
- Epiphyseal End of Long Bones
- Peak Incidence 20-40 Years
- Benign
- Knee Region
- Diagnosis
- Soap Bubble Appearance on X-ray
- Spindle-shaped Cells
- Multinucleated Giant Cells
46 secs
Osteosarcoma
- Pathophysiology
- Osteogenic Sarcoma
- Peak incidence men 10-20 years old
- Metaphysis of Long Bones
- Knee Region
- Radiation
- Familial Retinoblastoma
- Paget's Disease
- Diagnosis
- Codman Triangle
- Sunburst Pattern from Elevated Periosteum
- Grave Prognosis
2 mins
Ewing's Sarcoma
- Epidemiology
- Most Common in Boys < 15 years old
- Pathophysiology
- 11;22 Translocation
- Characteristics
- Long bones, Pelvis, Ribs
- Diaphysis
- Small Blue Cells
- Malignant
- Aggressive
- Onion-skin Appearance
- TREATMENT
- Responsive to Chemotherapy
2 mins
Chondrosarcoma
- Pathophysiology
- Cartilaginous tumor
- Malignant
- Men 30-60 years old
- Pelvic and femur bones
- Signs & Symptoms
- Glistening mass in medullary cavity
- Can be primary in origin or from osteochondroma
- Metastasize to lungs
1 min
Streptococcus Pyogenes Disease
- Pyogenic
- Pyogenic
- Pyogenic Pharyngitis
- Impetigo
- Cellulitis
- Toxigenic
- Toxic Shock-Like Syndrome
- Scarlet Fever
- Sandpaper Rash
- Strawberry Tongue
- Immunologic
- Immunologic
- Rheumatic Fever
- Antibodies to M Protein
- Acute Glomerulonephritis (Post Streptococcal Glomerulonephritis)
2 mins
Staphylococcus aureus Disease
- Skin Infections
- Impetigo
- Abscesses
- Exfoliative Toxin
- Scalded Skin Syndrome
- Toxic Shock Syndrome (TSST 1)
- Binds to MHC II and T Cell Receptor
- Food Poisoning
- Acute Bacterial Endocarditis
- Pneumonia
- Osteomyelitis
2 mins
Postoperative Fever
- 5 W's
- Wind (Days 1-3)
- Atelectasis
- Pneumonia
- Water (Days 3-5)
- Urinary Tract Infection from Catheter
- Walking (Days 4-6)
- Deep Vein Thrombosis (DVT)
- Pulmonary Embolism
- Wound (Days 5-7)
- Infection
- Wonder Drugs (Days 7+)
- Drugs
2 mins
Anterior Thigh Muscles
- Innervation
- Femoral Nerve
- Muscles
- Iliopsoas
- Psoas Innervated by L1-3
- Sartorius
- Pectineus
- Quadriceps Femoris
- Vastus Lateralis
- Vastus Intermedius
- Vastus Medialis
- Rectus Femoris
2 mins
Rheumatic Fever
- Pathophysiology
- Pharyngeal Infection with Strep Pyogenes (Group A Strep)
- Rheumatic Heart Disease
- Signs and Symptoms
- Aschoff Bodies
- Anitschkow's Cells
- Early Death Due to Myocarditis
- Migratory Polyarthritis
- Subcutaneous Nodules
- Erythema Marginatum
- Chorea
- Diagnosis
- Elevated ESR
2 mins
Syphilis
- Characteristics
- Treponema pallidum
- Spirochete with characteristic motility
- Signs and Symptoms
- Painless chancre
- Condylomata lata
- Generalized lymphadenopathy
- Rash on palms and soles
- Aortitis
- Gummas
- Neurosyphilis
- Argyll Robertson pupils
- Vasa vasorum
- Tabes dorsalis
- Treatment
- Penicillin
- Jarisch-Herxheimer reaction
2 mins
Schistosoma
- Pathophysiology
- Trematode (Fluke)
- Snail-infested Water
- Intense Immune Response
- Intestinal Disease
- Hepatosplenic Granuloma
- Squamous Cell Cancer of the Bladder
- Diagnosis
- Parasitic Antigens via ELISA
- Treatment
- Praziquantel
2 mins
Enterococci
- Characteristics
- Gram-Positive Cocci
- Catalase Negative
- 6.5% NaCl
- Grows in Bile
- Normal Colonic Flora
- Signs and Symptoms
- Urinary Tract Infection
- Subacute Endocarditis
- Penicillin Resistant
- VRE (Vancomycin Resistant Enterococci)
2 mins
Pseudomonas Aeruginosa Disease
- Signs and Symptoms
- Pneumonia
- Cystic Fibrosis
- Burn Wounds
- Hot tub folliculitis
- Urinary Tract Infections
- Osteomyelitis associated with IV drug use
- Osteomyelitis from Shoe Puncture Wound
- Diabetic Osteomyelitis
- Corneal Infections in contact lens users
- Endocarditis
- Ecthyma Gangrenosum
3 mins
Proteus Mirabilis
- Characteristics
- Gram-Negative
- Bacillus
- Oxidase Negative
- Urease-Positive
- Swarming Motility
- Non-lactose Fermenting
- Symptoms
- Urinary Tract Infection
- Struvite Crystals
- Staghorn Kidney Stones
2 mins
Clostridium perfringens
- Characteristics
- Gram-Positive
- Bacillus
- Anaerobe
- Spore-Forming
- Alpha Toxin Lecithinase
- Phospholipase
- Heat Labile Enterotoxin
- Signs and Symptoms
- Myonecrosis
- Gas Gangrene
- Food Poisoning and Diarrhea
- Treatment
- Hyperbaric O2 Chamber
2 mins
Vitamin C Mechanism and Deficiency
- Mechanism
- Ascorbic acid
- Antioxidant
- Protects Against Free Radicals
- Keeps Iron in Reduced State
- Hydroxylation of Proline and Lysine
- Necessary for Dopamine B Hydroxylase
- Deficiency Signs and Symptoms
- Scurvy
- Swollen Gums
- Bruising
- Poor Wound Healing
- Hemarthrosis
- Perifollicular Hemorrhages
- Anemia
4 mins
Ehlers-Danlos Syndrome Disease
- Pathophysiology
- Faulty Collagen Synthesis
- Autosomal Dominant or Recessive
- Various Severities
- Signs and Symptoms
- Hypermobile Joints
- Hyperextensible Skin
- Easy Bruising/Bleeding
- Berry (Saccular) Aneurysm
- Considerations
- Brighton Criteria
2 mins
Osteogenesis Imperfecta
- Pathophysiology
- Autosomal Dominant
- Decreased Type I Collagen Production
- Symptoms
- Phenotypically Diverse
- Brittle Bone Disease
- Fractures from Minimal Trauma
- Confused with Child Abuse
- Hearing Loss
- Dental Imperfections
- Blue Sclera
1 min
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