Becca Shared "Test #3" - 34 Picmonics
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Test #3
Gout Treatment
- Acute (Acute-angle)
- NSAIDs
- Glucocorticoids
- Colchicine
- Impairs Leukocyte Chemotaxis
- Chronic Gout (Crone Goat)
- Inhibit Xanthine Oxidase
- Allopurinol
- Febuxostat
- Inhibit Reabsorption of Uric Acid
- Probenecid
1 min
Class IB Antiarrhythmics (Na+ Channel Blockers)
- Indications
- Arrhythmias
- After Myocardial Infarction
- Mechanism of Action
- Affect Ischemic Tissue
- Decrease AP duration
- Drugs
- Mexiletine
- GI Upset
- Lidocaine
- CNS Depression
- Tocainide
- Phenytoin
- Hirsutism
2 mins
Prednisone (Glucocorticoids)
- Mechanism
- Glucocorticoid
- Indications
- Inflammatory Conditions
- Organ Transplant Rejection
- Side Effects
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Considerations
- Adrenal Insufficiency
- Taper Gradually
2 mins
ACE Inhibitors
- -Pril Suffix
- Indications
- Hypertension
- CHF
- Diabetic Nephropathy
- Mechanism of Action
- Inhibits ACE
- Decreases GFR
- Inhibits Constriction of Efferent Arteriole
- Side Effect
- Increased Bradykinin
- Cough
1 min
NSAIDs
- Indications
- Anti-inflammatory
- Analgesic
- Fever
- Closure of Patent Ductus Arteriosus
- Mechanism of Action
- Reversible Inhibition of COX-1 and COX-2
- Block Prostaglandin Synthesis
- Side Effects
- Interstitial Nephritis
- Gastric Ulcer
- Renal Ischemia
1 min
Acetaminophen
- Indications
- Fever
- Pain
- Mechanism of Action
- Reversibly Inhibits COX
- Acts Primarily in CNS
- Side Effect
- Hepatic Necrosis
- N-acetylcysteine Antidote
51 secs
Metformin
- Indications
- Diabetes Mellitus Type 2
- Polycystic Ovary Syndrome (PCOS)
- Mechanism of Action
- Decreased Gluconeogenesis
- Increased Insulin Sensitivity
- Side Effects
- Lactic Acidosis
- GI Distress
- Weight Loss
- B12 Deficiency
- Contraindication
- GFR < 30 ml/min
2 mins
Sitagliptin (Januvia) and Saxagliptin (Onglyza) (DPP-4 Inhibitors)
- -gliptin Suffix
- Mechanisms
- DPP-4 Inhibitor
- Increases Insulin Release
- Indications
- Type 2 Diabetes
- Side Effects
- Pancreatitis
- Upper Respiratory Infection and Inflammation
- Stevens-Johnson Syndrome
- Considerations
- Used as Add-on Agents
2 mins
Exenatide (Byetta)
- Mechanism
- Incretin Mimetic
- GLP-1 Synthetic Analog
- Indications
- Type 2 Diabetes
- Side Effects
- Hypoglycemia
- Nausea and Vomiting
- Diarrhea
- Thyroid Cancer
- Pancreatitis
- Renal Failure
- Considerations
- (Give Exenatide) One Hour After Other Medications
- Adjunct Therapy
3 mins
Chlorpropamide and Tolbutamide (Orinase) (1st Generation Sulfonylureas)
- Mechanisms
- 1st Generation Sulfonylureas
- Stimulate Release of Insulin
- Indications
- Type 2 Diabetes
- Side Effects
- Hypoglycemia
- Possible Cardiovascular Toxicity
- Weight Gain
- Considerations
- Exacerbated Hypoglycemia with Beta-blockers
- Avoid During Pregnancy and Breast Feeding
- Avoid Alcohol
2 mins
Bile Acid Resins
- Indications
- Hyperlipidemia
- Mechanism of Action
- Bile Acid Reabsorption Prevented
- Slight Increase HDL/Triglycerides
- Decrease LDL
- Drugs
- Colestipol (Colestid)
- Cholestyramine
- Colesevelam
- Side Effects
- Cholesterol Gallstones
- Decreased Absorption of Fat-soluble Vitamins
- Patients Hate It
2 mins
Pioglitazone (Thiazolidinediones)
- -glitazones Suffix
- Mechanism
- Binds PPAR-Gamma
- Decreases Insulin Resistance
- Indications
- Type 2 Diabetes
- Side Effects
- Weight Gain
- Heart Failure
- Myalgia
- Hypoglycemia
- Upper Respiratory Infection
- Considerations
- Increased Risk of Bladder Cancer
- Increased Fracture Risk in Women
- Monitor Liver Enzymes
2 mins
Acarbose (Precose) and Miglitol (Glyset) (Alpha Glucosidase Inhibitors)
- Mechanisms
- Alpha Glucosidase Inhibitors
- Delays Absorption of Carbohydrates
- Indications
- Type 2 Diabetes
- Side Effects
- Flatulence
- Diarrhea
- Anemia
- Cramps
- Considerations
- Monitor LFTs
- Oral Glucose for Hypoglycemia
2 mins
Pramlintide (Symlin)
- Mechanism
- Synthetic Amylin Analog
- Indications
- Diabetes Type 1 and 2
- Supplement Mealtime Insulin
- Side Effects
- Nausea
- Skin Reactions at Injection Site
- Considerations
- Hypoglycemia When Combined with Insulin
- Delayed Absorption of Oral Drugs
2 mins
Angiotensin Receptor Blockers (ARBs)
- -sartan suffix
- Indications
- Hypertension
- CHF
- Diabetic Nephropathy
- Mechanism of Action
- Angiotensin II Receptor Blockers
- Side Effect
- Hyperkalemia
- Contraindication
- Pregnancy
1 min
Digoxin Toxicity Treatment
- Activated Charcoal
- Slowly Normalize K+
- Digibind (Anti-Digoxin Fab)
- Magnesium Sulfate
- Lidocaine
- Cardiac Pacing
2 mins
Warfarin
- Mechanism of Action
- Interferes with Vitamin K-dependent Clotting Factors
- Extrinsic Pathway
- Bridge with Heparin
- Indications
- Chronic Anticoagulation
- Side Effects
- Bleeding
- Necrosis
- Cytochrome P450
- Contraindications
- Pregnancy
- Antidote
- FFP + Vitamin K
2 mins
Ibuprofen (Advil, Motrin)
- Mechanisms
- NSAID
- COX Inhibitor
- Indications
- General Pain
- Fever
- Inflammatory Conditions
- Side Effects
- GI Ulcers
- Nephrotoxicity
- Rash
- Considerations
- Avoid with Alcohol
- Risk of Thrombotic Event
2 mins
Thyroid Gland
- Characteristics
- TSH Stimulates T3 and T4 Release
- Metabolism Regulation
- Blood Calcium Sensor
- Calcitonin Release
- Blood Calcium Decreases
- Bone Building
2 mins
Levothyroxine
- Indications
- Hypothyroidism
- Myxedema Coma
- Mechanism of Action
- Isomer of Thyroid Hormone (T4)
- T3 has Higher Potency
- Side Effects
- Hyperthyroid Symptoms
57 secs
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