Steven Shared "Highest High Yield: 10-Day Step 1 Study Schedule" - 38 Picmonics
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Highest High Yield: 10-Day Step 1 Study Schedule
Severe Combined Immunodeficiency (SCID)
- Both B and T Cell Deficiency
- Recurrent Viral, Bacterial, Fungal, Protozoal Infections
- Defective Interleukin (IL) 2 Receptor
- X-Linked
- Adenosine Deaminase Deficiency
- Failure to Synthesize MHC II Antigens
- Treat with Bone Marrow Transplant
2 mins
Bruton's Agammaglobulinemia
- Pathophysiology
- X-linked Recessive
- Defective Bruton Tyrosine Kinase
- Blocks B Cell Maturation
- Signs & Symptoms
- Decreased Immunoglobulins of All Classes
- Bacterial Infections After Six Months
- Maternal IgG Protects Before Six Months
2 mins
Common Variable Immunodeficiency
- Pathophysiology
- Defect in B Cell Maturation
- Decreased Plasma Cells
- Decreased Immunoglobulins
- Signs & Symptoms
- Sinopulmonary Infections
- Increased Risk of Autoimmune Disease
- Lymphoma
1 min
Digoxin Mechanism and Indication
- Direct inhibition of Na K ATPase
- Indirect inhibition of Na Ca exchanger
- Increase Ca in cell
- Positive Inotropy
- CHF
- Stimulates Vagus Nerve
- Decreased conduction at AV node
- Atrial Fibrillation
1 min
Acute Digoxin Toxicity
- Clinical Symptoms
- Hyperkalemia
- Cholinergic (Nausea, Vomiting, Diarrhea)
- Blurry Yellow Green Vision with Halo of Light
- Arrhythmia
- Bradycardia
- EKG Changes
- Prolonged PR interval
- Decreased QT
- Scooping on EKG
- T Wave Inversion
2 mins
Multiple Myeloma Pathophysiology
- Pathophysiology
- Monoclonal Plasma Cell Cancer
- Clock Face Chromatin
- Diagnosis
- M Spike on Protein Electrophoresis
- Increased IgG and IgA
- Fried Egg Appearance (BM Biopsy)
- Rouleaux Formation
- Stacked RBC's
- Bence Jones Protein
2 mins
Multiple Myeloma Signs and Symptoms
- Signs and Symptoms
- Increased Susceptibility to Infection
- Back/Bone Pain
- Punched Out Lytic Bone Lesions
- Hypercalcemia
- Primary Amyloidosis
- Renal Insufficiency
- Anemia
2 mins
Dilated Cardiomyopathy
- Chronic Alcohol Abuse
- Doxorubicin Toxicity
- Cocaine Use
- Wet Beriberi
- Hemochromatosis
- Coxsackie B
- Chagas Disease
- Peripartum
- S3
- Eccentric Hypertrophy
2 mins
Restrictive Cardiomyopathy
- Sarcoidosis
- Amyloidosis
- Post-radiation Fibrosis
- Endocardial Fibroelastosis
- Löffler's or Loeffler's Syndrome with Eosinophilia
- Hemochromatosis
2 mins
Bacterial Endocarditis
- Signs and Symptoms
- Fever
- New murmur
- Janeway Lesions
- Splinter Hemorrhages
- Roth spots/round white spots on retina
- Osler nodes/tender lesions on finger or toe pads
- Anemia
2 mins
Rheumatic Fever
- Pathophysiology
- Pharyngeal Infection with Strep Pyogenes (Group A Strep)
- Rheumatic Heart Disease
- Signs and Symptoms
- Aschoff Bodies
- Anitschkow's Cells
- Early Death Due to Myocarditis
- Migratory Polyarthritis
- Subcutaneous Nodules
- Erythema Marginatum
- Chorea
- Diagnosis
- Elevated ESR
2 mins
Focal Segmental Glomerulosclerosis
- Most Common Cause of Nephrotic Syndrome in Hispanic People and African Americans
- Associated with Sickle Cell Disease and HIV
- Associated Interferon Therapy and Heroin Abuse
- Histopathology
- LM Segmental Sclerosis and Hyalinosis
- EM Focal Damage of Visceral Epithelial Cells
- IF Negative
- Signs & Symptoms
- Microscopic Hematuria
- Nonselective Proteinuria
- Considerations
- Poor Prognosis
2 mins
Rapidly Progressive Glomerulonephritis
- Pathogenesis
- Nephritic Syndrome
- Crescent Shape
- Crescents Consist of Fibrin and C3b
- With Parietal Cells, Monocytes, and Macrophages
- IMMUNOFLUORESCENCE
- Linear Immunofluorescence
- Negative Immunofluorescence
- Granular Immunofluorescence
- Etiology
- Goodpasture Syndrome
- Granulomatosis with Polyangiitis (Formerly Wegener's)
- Microscopic Polyangiitis
- Prognosis
- Poor Prognosis
3 mins
Maple Syrup Urine Disease
- Pathophysiology
- Defect in alpha ketoacid dehydrogenase
- Blocked degradation of branched chain amino acids
- Leucine
- Isoleucine
- Valine
- Signs and Symptoms
- Seizures
- Intellectual Disability
1 min
Pyruvate Dehydrogenase Deficiency
- Characteristics
- Acquired from Thiamine Deficiency
- Backup of Alanine and Pyruvate
- Symptoms and Complications
- Neurologic Defects
- Lactic Acidosis
- Interventions
- Ketogenic Nutrients
- Lysine and Leucine (Ketogenic Nutrients)
57 secs
Campylobacter jejuni
- Characteristics
- Gram-Negative
- Bacillus
- Flagella
- Curved
- Corkscrew Appearance
- Oxidase-Positive
- Grows Well at 42 Degrees
- Undercooked Meat
- Unpasteurized Milk
- Animals with Diarrhea
- Signs and Symptoms
- Bloody Diarrhea
- Guillain-Barre syndrome
- Reactive Arthritis
3 mins
Syphilis
- Mechanism
- Treponema pallidum
- Assessment
- Primary Stage
- Painless Chancre
- Secondary Stage
- Rash on Palms and Soles
- (Generalized) Lymphadenopathy
- Condylomata Lata
- Latent Stage
- Asymptomatic
- Tertiary (Late) Stage
- Aortitis
- Neurosyphilis
- Gummas
- Interventions
- Penicillin
- Jarisch-Herxheimer Rash
3 mins
Clostridium botulinum
- Characteristics
- Bacillus
- Gram-positive
- Anaerobe
- Spore-forming
- Heat Labile Toxin
- Inhibits Acetylcholine (Ach) Release at Neuromuscular Junction (NMJ)
- Canned Food in Adults
- Spores in Honey
- Signs and Symptoms
- Descending Flaccid Paralysis
- Diplopia
- Ptosis
- Floppy Baby
- Constipation
2 mins
Corynebacterium diphtheriae
- Characteristics
- Gram-Positive
- Bacillus
- Exotoxin
- ADP Ribosylation of Elongation Factor 2
- Beta Prophage
- Lysogeny
- Tellurite Agar
- Chinese Letters
- Metachromatic Blue Red Granules
- Aniline Stains Deeply Methylene Blue
- Signs and Symptoms
- Pseudomembranous Pharyngitis
- Lymphadenopathy
- Myocarditis
- Polyneuritis
3 mins
Adenovirus
- Characteristics
- Non-enveloped
- Icosahedral
- Linear
- Double Stranded DNA
- Signs and Symptoms
- Pharyngitis
- Conjunctivitis
- Fever
- Summer Swimming
- Day Care Centers
- Acute Hemorrhagic Cystitis
- Pneumonia
1 min
