Jon Shared "MS2 - Neuro" - 61 Picmonics
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MS2 - Neuro
Lambert-Eaton Syndrome
- Mechanism
- Autoantibody to the Presynaptic Calcium Channel on Motor Neurons
- Inhibits Acetylcholine (ACh) Release at Neuromuscular Junction
- Paraneoplastic Syndrome
- Small Cell Lung Cancer
- Symptoms
- Proximal Muscle Weakness
- Improves with Muscle Use
- Autonomic Symptoms
- Extraocular Muscle Sparing
2 mins
Carpal Tunnel Syndrome
- Median Nerve Entrapment
- Compression at Carpal Tunnel
- Numbness, Tingling and Pain in Hand
- Diagnosis
- Phalen's Maneuver
- Tinel's Sign
- Treatment
- Splints
- Surgery
- Steroids
2 mins
Vitamin B6 (Pyridoxine) Deficiency
- Deficiency From Isoniazid
- Deficiency From Oral Contraceptives
- Seizures
- Hyperirritability
- Peripheral Neuropathy
- Sideroblastic Anemia
3 mins
Phenytoin
- Indications
- Status Epilepticus
- Tonic-Clonic Seizures
- Mechanism of Action
- Blocks Na+ Channel Activation
- Inhibition of Glutamate Release
- Class IB Antiarrhythmic
- Side Effects
- Teratogenic
- Macrocytic Megaloblastic Anemia
- Induce Cytochrome P450
- Drug-induced Lupus
- Neuropathy
- Hirsutism
- Gingival Hyperplasia
1 min
Gabapentin
- Primary Indication
- Seizure Treatment
- Secondary Indications
- Peripheral Neuropathy
- Postherpetic Neuralgia
- Bipolar Disorder
- Migraine Prophylaxis
- Characteristics
- Inhibits Voltage-Gated Ca2+ channels
- Designed as a GABA Analog
- Side Effects
- Ataxia
- Sedation
2 mins
Guillain-Barre Syndrome Assessment
- Assessment
- Ascending Paralysis
- Muscle Weakness
- Paresthesias (Pins and Needles)
- Diplopia
- Difficulty Speaking
- Dysphagia
- Labile Blood Pressure
- Loss of Bowel and Bladder Control
- Considerations
- Aggressive Airway Management
2 mins
Amyotrophic Lateral Sclerosis (ALS)
- Assessment
- Progressive Muscle Weakness
- Systemic Muscle Wasting
- Fasciculations
- Spasticity
- Fatigue
- Considerations
- Riluzole (Rilutek)
- Stretching
- Little to No Cognitive Decline
- Respiratory Support
- Palliative Care
2 mins
Multiple Sclerosis Features and Mechanisms
- Features
- More Common in Women
- Presents in 20's and 30's
- Northern Europeans
- Mechanism
- Unknown mechanism, genetic factor
- HLA-DRB1
- Autoimmune Demyelination of CNS
- White Matter of Brain and Spinal Cord
- T Cell Mediated Inflammation
2 mins
Multiple Sclerosis Symptoms and Diagnosis
- Symptoms
- Optic Neuritis
- Internuclear Ophthalmoplegia
- Scanning Speech
- Urinary and Fecal Incontinence
- Motor Issues (Intention Tremor, Paresis)
- Numbness and Pain
- Depression
- Relapsing Symptoms
- Diagnosis
- Gold Standard = Plaques on MRI
- Increased CSF Immunoglobulins (IgG)
- Oligoclonal Bands
4 mins
Parkinson's Disease Assessment
- Assessment
- Decreased Dopamine
- Older Adult
- Cogwheel Rigidity
- Bradykinesia
- Shuffling Gait
- Resting Tremor
- Pill-Rolling
- Mask-Like Face
- Cognitive Decline
2 mins
Parkinson's Disease Interventions
- Medications
- Levodopa/Carbidopa (Sinemet)
- Entacapone (Comtan)
- Selegiline (Eldepryl)
- Amantadine (Symmetrel)
- Bromocriptine (Parlodel)
- Benztropine (Cogentin)
- Considerations
- Allow Extra Time
- Ensure Patient Safety
- Surgery As Last Resort
2 mins
Lewy Body Dementia
- Pathophysiology
- Unknown Etiology
- Decreased Acetylcholine
- Alpha-synuclein Defect
- Eosinophilic Cytoplasmic Inclusion
- Signs and Symptoms
- Visual Hallucinations
- Progressive Dementia
- Fluctuating Cognition
- REM Sleep Behavior Disorder
- Parkinsonism
- Treatment
- Acetylcholinesterase Inhibitors
3 mins
5 A's of Alzheimer's Disease
- Agnosia
- Anomia
- Aphasia
- Apraxia
- Amnesia
1 min
Alzheimer's Disease Assessment (Early Symptoms)
- Risk Factors
- Advanced Age
- Early Signs and Symptoms
- Poor Judgment and Decision-Making
- Difficulty Having a Conversation
- Inability to Manage a Budget
- Losing Track of the Date or Season
- Misplacing Things
1 min
Alzheimer's Disease Interventions
- Diagnostic Tests
- PET Scan and CT
- Mini-Mental State Examination
- Interventions
- Drug Therapy
- Safe Environment
- Moderate Exercise
- Behavioral Modification
- Assistance with Functional Independence
- Assistance and Support for Caregiver
2 mins
Alzheimer's Disease Assessment (Late Symptoms)
- Late Signs and Symptoms
- Memory Impairment
- Wandering Behavior
- Confabulation
- Perseveration
- Lack of Abstract Thinking
- Severe Cognitive Decline
1 min
Kluver-Bucy Syndrome
- Bilateral Amygdala Lesion
- Associated with HSV-1
- Hyperorality
- Hypersexuality
- Disinhibited Behavior
1 min
Types of Strokes
- Warning Signs
- Transient Ischemic Attack (TIA)
- Reversible Ischemic Neurologic Deficit (RIND)
- Types
- Ischemic
- Thrombotic
- Atherosclerosis
- Embolic
- Atrial Fibrillation
- Hemorrhagic
- Severe Hypertension
3 mins
Left Hemisphere Stroke Assessment
- Opposite Side Weakness (Hemiplegia)
- Side to Side Discrimination
- Aphasia
- Agraphia
- Slow Performance
- Aware of Deficits
- Anxiety
- Depression
2 mins
Right Hemisphere Stroke Assessment
- Opposite Side Weakness (Hemiplegia)
- Poor Proprioception
- Disoriented to Person, Place, Time
- Can't Recognize Faces (Prosopagnosia)
- Loss of Judgement and Awareness
- Impulsiveness
- Personality Changes
- Tonal Hearing Loss
2 mins
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