Chuck Shared "ID-CUMULATIVE-UMMS" - 133 Picmonics
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ID-CUMULATIVE-UMMS
1st Generation Cephalosporin
- Drug Names
- Cefazolin
- Cephalexin
- Indications (PEcK Mnemonic)
- Proteus mirabilis
- E. coli
- Klebsiella
- Gram-Positive Cocci
1 min
2nd Generation Cephalosporin
- Drug Names
- Cefoxitin
- Cefaclor
- Cefuroxime
- Indications (PEcK HENS Mnemonic)
- Proteus mirabilis
- E. coli
- Klebsiella
- Gram-Positive Cocci
- Haemophilus influenzae
- Enterobacter
- Neisseria
- Serratia marcescens
2 mins
3rd Generation Cephalosporin
- Drug Names
- Cefotaxime
- Ceftriaxone
- Cefdinir
- Ceftazidime
- Pseudomonas
- Indications
- Serious Gram-Negative Bacteria Resistant to Other Beta-Lactams
1 min
4th Generation Cephalosporin
- Drug Name
- Cefepime
- Indications
- Increased Activity Against Gram-Positive Infections and Pseudomonas
29 secs
5th Generation Cephalosporin
- Mechanism
- Beta-Lactam
- Indications
- Resistant Bacteria
- Broad Spectrum Gram-Positive and Gram-Negative
- Drugs
- Ceftobiprole
- Has Pseudomonas Coverage
- Ceftaroline
- No Pseudomonas Coverage
1 min
Adenovirus
- Characteristics
- Non-enveloped
- Icosahedral
- Linear
- Double Stranded DNA
- Signs and Symptoms
- Pharyngitis
- Conjunctivitis
- Fever
- Summer Swimming
- Day Care Centers
- Acute Hemorrhagic Cystitis
- Pneumonia
1 min
Aminoglycosides
- Drug Names
- Gentamicin
- Neomycin for Bowel Surgery Prep
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Inhibit Formation of Initiation Complex
- Cause Misreading of mRNA
- Require O2 for Uptake
- Resistance
- Resistance by Transferase Enzymes
- Acetylation
- Phosphorylation
- Adenylation
- Indications
- Gram-Negative Rod Infections
- Synergistic with B-Lactam Antibiotics
- Side Effects
- Nephrotoxicity Especially When Used with Cephalosporins
- Ototoxicity Especially When Used with Loop Diuretics
- Teratogen
5 mins
Amphotericin B
- Indications
- Systemic Mycosis
- Fungal Meningitis
- Last Resort for Protozoan infections
- Mechanism
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
1 min
Amphotericin B Side Effects & Toxicity
- Side Effects
- Fever/Chills "Shake and Bake"
- Nephrotoxicity
- Milder with Liposomes
- Hypotension
- Anemia
- IV Phlebitis
- Arrhythmias
1 min
Aspergillus fumigatus
- Characteristics
- Fungi
- Monomorphic
- Septate Hyphae
- Branch at Acute Angles
- Fruiting Bodies
- Disease
- Allergic Bronchopulmonary Aspergillosis (ABPA)
- Eosinophilia
- Increased IgE
- Glucocorticoids +/- Azoles
- Pulmonary Aspergillosis
- TB Cavity
- Lung Aspergilloma
- Hemoptysis
- Invasive Aspergillosis
- AIDS/Immunocompromised
- Chronic Granulomatous Disease
- Hemorrhagic Infarction
- Necrotizing Bronchopneumonia
- Voriconazole +/- Caspofungin
3 mins
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
Bacteroides Fragilis
- Characteristics
- Gram-Negative
- Anaerobe
- Normal Colonic Flora
- Produces Vitamin K
- Produces Gas in Tissue
- Foul-Smelling
- Signs and Symptoms
- Gastrointestinal Abscess
- Treatment
- Penicillin-Resistant
- Clindamycin
- Metronidazole
2 mins
Beta-Lactamase Inhibitors
- Considerations
- Often Combined with Penicillin Antibiotics
- Drug Names
- Clavulanic Acid
- Sulbactam
- Tazobactam
51 secs
Blastomyces
- Characteristics
- Fungi
- Hyphae Form at 20°-25°C
- Yeast Form at 37°C
- Round Yeast
- 5-15 Micrometer (um or μm)
- Single Broad-Based Buds
- Thick Doubly-Refractive Walls
- East of the Mississippi River and Around the Great Lakes
- Signs and Symptoms
- Pneumonia
- Skin Infection
- Bone Infection
- Granulomatous Response
- Treatment
- Itraconazole
- Amphotericin B
3 mins
Campylobacter jejuni
- Characteristics
- Gram-Negative
- Bacillus
- Flagella
- Curved
- Corkscrew Appearance
- Oxidase-Positive
- Grows Well at 42 Degrees
- Undercooked Meat
- Unpasteurized Milk
- Animals with Diarrhea
- Signs and Symptoms
- Bloody Diarrhea
- Guillain-Barre syndrome
- Reactive Arthritis
3 mins
Candida Albicans
- Fungi
- Yeast with Pseudohyphae at 20 Degrees C
- Germ Tube Formation at 37 Degrees C
- Pruritic Vaginitis
- White Cottage Cheese Discharge
- Fiery Red Mucosa
- Diabetics
- Antibiotic Use
- Esophageal Thrush in Immunocompromised
- Diaper Rash
- Endocarditis in IV Drug Users
2 mins
Cephalosporins Overview
- Mechanism of Action
- Beta lactam drug
- Inhibits cell wall synthesis
- Bactericidal
- Side Effects
- Hypersensitivity reactions
- Vitamin K Deficiency
- Disulfiram like reaction with Alcohol
- Increased Nephrotoxicity of Aminoglycosides
1 min
Chlamydia trachomatis
- Characteristics
- A to C
- Trachoma
- Follicular Conjunctivitis
- Blindness
- Africa
- L1 to 3
- Lymphogranuloma venereum
- Buboes
- Genital Ulcer
- D to K
- Urethritis and PID
- Neonatal Pneumonia
- Staccato Cough
- Neonatal Conjunctivitis
2 mins
Chloramphenicol
- Mechanism
- Bacteriostatic
- Inhibits 50S Peptidyltransferase Activity
- Indications
- Meningitis
- Rocky Mountain Spotted Fever in Pregnant Women
- Side Effects
- Anemia
- Aplastic Anemia
- Gray Baby Syndrome due to Decreased UDP-Glucuronyl Transferase
- Resistance Caused by Plasmid Encoded Acetyltransferase
2 mins
Cidofovir
- Indications
- CMV Retinitis
- Acyclovir-Resistant HSV
- Mechanism
- Inhibits Viral DNA Polymerase
- Side Effects
- Nephrotoxicity
- Administer with Probenecid and IV Saline
1 min
