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Immunology & Oncology | Medicine (MD/DO) School Study Aid
Innate Immunity Cellular Response
- Characteristics
- Natural Killer Lymphocytes Attack Abnormal Cells
- Neutrophils in Blood
- Infected Cells Release Interferon
- Complement Proteins Lyse Pathogens/Infected Cells
- Dendritic Cells in Tissue
- Macrophages in Tissue
2 mins
Humoral Adaptive Immunity
- Characteristics
- B Cell Binds Free Floating Antigen
- B Cell Presents Antigen to Helper T Cell
- Helper T Cells Help B Cells Develop Antigen Specificity
- Plasma B Cells Secrete Antibodies
- Memory B Cells Cause Faster Secondary Response
2 mins
Cell-mediated Adaptive Immune Response
- Characteristics
- Macrophages and Dendritic Cells Present Antigens
- T Cell Develops Antigen Specificity
- Regulatory T Cells Suppress Response
- Memory T Cells Cause Faster Secondary Response
- Cytotoxic T Cells Lyse Infected Cells
- Infected Cells Present Antigen On Surface
2 mins
Inflammatory Response
- Pathogens Infect Tissue
- Mast Cells Release Histamine
- Histamine Dilates and Increases Capillary Permeability
- Macrophages Engulf Pathogens
- Macrophage Signals Cells With Cytokines
- Responding Neutrophils Cross Capillary Wall
- B And T Lymphocytes Arrive At Injury Site
2 mins
Cancer Warning Signs (CAUTION)
- CAUTION
- Change in Bowel or Bladder Habits
- A Sore That Does Not Heal
- Unusual Bleeding or Discharge
- Thickening or Lump in the Breast or Elsewhere
- Dyspepsia (Indigestion)
- Obvious Change to Warts or Moles
- Nagging Cough
1 min
Hallmarks of Cancer
- Growth Signals
- Growth Signal Self-sufficiency
- Anti-growth Signal Insensitivity
- Control of Replication
- Evasion of Apoptosis
- Limitless Replication
- Progression/Spread
- Angiogenesis
- Tissue Invasion
- Metastasis
- Warburg Effect
- Immune Evasion
2 mins
Allergic Contact Dermatitis
- Pathophysiology
- Type IV Hypersensitivity
- Physical Contact with Allergen
- Nickel
- Neomycin
- Poison Ivy
- Clinical Features
- Urticaria
- Pruritus
- Erythematous, Vesicular
- Diagnosis
- Patch Testing
- Treatment
- Avoid Cause
- Topical Hydrocortisone
- Antihistamines
- Cool Water Soaks
2 mins
Immunoglobulin Isotypes
- IgM
- Primary Immune Response
- Cold Agglutinin Autoimmune Hemolytic Anemia (C-AIHA)
- IgG
- Crosses Placenta
- Warm Agglutinin Autoimmune Hemolytic Anemia (W-AIHA)
- IgA
- Released in Secretions, Mucosal Fluids, and Breast Milk
- IgD
- IgE
- Against Parasitic Worms
- Allergic Reaction
3 mins
Graft Versus Host Disease
- Pathophysiology
- Graft T Cell Sensitization Against Host MHC Antigens
- Graft Recognizes Host as "Foreign"
- Type IV Hypersensitivity
- Signs and Symptoms
- Diffuse Maculopapular Rash
- Jaundice
- Diarrhea
- Hepatosplenomegaly
- Associations
- Severe Immunocompromised Patients
- Bone Marrow and Liver Transplantation
- Transfusion of Non-irradiated Blood
2 mins
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