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Medicine (MD/DO)
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USMLE Step 1
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Microbiology
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Single-stranded Negative-sense RNA Viruses

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Microbiology | Medicine (MD/DO) School Study Aid

Single-stranded Negative-sense RNA Viruses
12 Picmonics to Learn | 21 mins
Paramyxovirus
Characteristics
Enveloped
RNA Virus
Helical
SS Negative Linear
Nonsegmented
Surface Fusion Protein Causes Multinucleated Cells
Presentation
Measles
Mumps
Bronchiolitis in Babies
Viruses
Parainfluenza
Respiratory Syncytial Virus (RSV)
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2 mins
Parainfluenza Virus
Characteristics
Paramyxovirus
Signs and Symptoms
Croup
Barking Seal Cough
Inspiratory Stridor
Steeple Sign
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2 mins
Croup (Laryngotracheobronchitis)
Mechanism
Parainfluenza Virus
Assessment
3 Months to 3 Years
Nighttime
Barking Seal Cough
Inspiratory Stridor
Interventions
Cool Humidified Air
Dexamethasone
Racemic Epinephrine
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2 mins
Respiratory Syncytial Virus (RSV) Assessment
Mechanism
Viral Infection Affecting Epithelial Cells
Signs and Symptoms
Begins After a Upper Respiratory Infection
Copious Secretions
Coughing and Sneezing
Wheezing
Otitis Media or Conjunctivitis (Possible Ear or Eye Drainage)
Poor Feeding
Tachypnea
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2 mins
Respiratory Syncytial Virus (RSV) Interventions
Prophylaxis
Palivizumab (Synagis)
Management
Hospitalization
Contact Precautions
Oxygen
Separate Room
Maintain Fluid Intake
Short-acting Beta-Agonist Bronchodilator
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2 mins
Rubeola Virus
Characteristics
RNA Virus
Paramyxovirus
Signs and Symptoms
Measles
Rash Spreads From Head to Toe
Koplik Spots First
Red Spots with Blue-White Center on Buccal Mucosa
Cough
Coryza
Conjunctivitis
Subacute Sclerosing Panencephalitis
Giant Cell Pneumonia in Immunosuppressed Patients
Warthin-Finkeldey Multinucleated Giant Cells
Treatment
Vitamin A
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3 mins
Mumps Virus
Characteristics
Paramyxovirus
Signs and Symptoms
Parotitis
Increased Serum Amylase
Orchitis
Oophoritis
Aseptic Meningitis
Pancreatitis
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59 secs
Influenza Virus
Characteristics
RNA Virus
Orthomyxovirus
Enveloped
Negative Sense
8 Segments
Helical
Hemagglutinin for Viral Entry
Neuraminidase for Virion Release
Genetic Shift
Reassortment of genome to cause major change
Genetic Drift
Minor Antigenic Mutations
Considerations
Reye Syndrome with Aspirin Use
Guillain-Barre Syndrome
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3 mins
Rabies Virus
Characteristics
Enveloped
RNA Virus
SS Negative Linear
Helical
Bullet-Shaped Envelope
Binds to Acetylcholine Receptor
Retrograde Fashion
Migrates to Saliva
Diagnosis
Negri Bodies
Cytoplasmic Inclusions in Neurons
Purkinje Cells of Cerebellum
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2 mins
Rabies Symptoms and Animals
Characteristics
Bats, Skunks, and Raccoons (Inside United States)
Dog Bites (Outside United States)
Fever
Agitation
Paralysis
Hydrophobia
Photophobia
Considerations
Fatal If Not Treated
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1 min
Ebola Virus
RNA Virus
Filovirus
Marburg Virus
Linear
Helical
Enveloped
Negative Sense
Bat Reservoir
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1 min
Ebola Virus Symptoms
10 Day Incubation
Flu-like Symptoms
Impaired Blood Clotting
Hematemesis and Hemoptysis
Mucous Membrane Bleeding
Skin Bruising
Internal Hemorrhage
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1 min

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