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Pathology | Medicine (MD/DO) School Study Aid
Lung Cancers
5 Picmonics to Learn | 11 mins
Adenocarcinoma of the Lung
- Characteristics
- Most Common Lung Cancer
- Most Common in Nonsmokers
- Peripheral Location
- KRAS, EGFR, and ALK Mutations
- Diagnosis
- Glandular Pattern
- Often Stains with Mucin
- Clinical Features
- Presents with Hemoptysis
- Clubbing
- Treatment
- Surgical Resection
- Chemotherapy and Radiation
2 mins
Squamous Cell Carcinoma of the Lung
- Characteristics
- Strong Correlation with Smoking
- More Common in Men
- Central Location
- Cavitating Lesion Extending to Hilum
- PTHrP Causes Hypercalcemia
- Diagnosis
- Keratin Pearls
- Intercellular Bridges
- Treatment
- Surgical Resection (if Early Stage)
- Chemotherapy and Radiation (if Later Stage)
2 mins
Small Cell (Oat Cell) Carcinoma
- Characteristics
- Aggressively Malignant
- Strong Correlation with Smoking
- Central Location
- Amplification of Myc Oncogenes
- Signs and Symptoms
- Narrowing of Bronchial Airways
- Cushing's Syndrome
- Ectopic ACTH
- Syndrome Of Inappropriate Antidiuretic Hormone (SIADH)
- Lambert-Eaton Syndrome
- Diagnosis
- Kulchitsky Cells
- Neuron-Specific Enolase Positive
- Chromogranin A Positive
- Treatment
- Chemotherapy and Radiation
3 mins
Large Cell Carcinoma
- Characteristics
- Strong Correlation with Smoking
- Poor Prognosis
- Peripheral Lesions
- Symptoms
- Gynecomastia
- Galactorrhea
- Diagnosis
- Anaplastic Cells
- Pleomorphic Giant Cells
- May Produce Beta hCG
- Diagnosis of Exclusion
- Treatment
- Surgical Resection
- Less Responsive to Chemotherapy and Radiation
2 mins
Bronchial Carcinoid Tumor
- Characteristics
- Excellent Prognosis
- Signs and Symptoms
- Symptoms of Bronchial Obstruction
- Often Asymptomatic
- Carcinoid Syndrome
- Diarrhea
- Wheezing
- Flushing
- Diagnosis
- 5-HIAA in Urine
- Nests of Neuroendocrine Cells
- Chromogranin A Positive
- Treatment
- Surgical Resection
- Octreotide for Symptomatic Relief
2 mins
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