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Pharmacology | Medicine (MD/DO) School Study Aid
First Generation Antihistamines
- Mechanism of Action
- Histamine H1 Receptor Antagonist
- Indications
- Allergies
- Nausea and Vomiting
- Motion Sickness
- Anaphylaxis
- Drug Names
- Diphenhydramine (Benadryl)
- Promethazine (Phenergan)
- Chlorpheniramine
- Side Effects
- Sedation
- Anticholinergic Effects
2 mins
Second Generation Antihistamines
- Indications
- Allergies
- Mechanism of Action
- Lipophobic
- Histamine H1 Receptor Antagonist
- Drugs
- Azelastine + Fluticasone (Dymista)
- Intranasal Spray
- Cetirizine (Zyrtec)
- Loratadine (Claritin)
- Fexofenadine (Allegra)
- Considerations
- Fewer Anticholinergic Effects
- Fewer CNS Effects
2 mins
Prostacyclin Analogs
- Mechanism of Action
- Prostaglandin I2 (Prostacyclin)
- Vasodilation of Pulmonary and Systemic Arteries
- Inhibits Platelet Aggregation
- Indications
- Pulmonary Hypertension
- Side effects
- Flushing
- Jaw Pain
- Drugs
- Epoprostenol
- Iloprost
- Treprostinil
1 min
Endothelin Receptor Antagonists
- Indication
- Pulmonary Hypertension
- Mechanism of Action
- Competitive Antagonism of Endothelin Receptors
- Decreased Pulmonary Vascular Resistance
- Drugs
- Bosentan
- Side Effects
- Hepatotoxicity
- Monitor LFTs
1 min
Dextromethorphan
- Mechanism
- Codeine Analog
- Weak Opioid
- NMDA Receptor Antagonist
- Uses
- Cough Suppressant
- Adverse Effects
- Serotonin Syndrome
- Drug Overdose
- Naloxone
2 mins
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