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Medicine (MD/DO)
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USMLE Step 2
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Endocrinology
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Hypothalamic-Pituitary Hormones

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Endocrinology | Medicine (MD/DO) School Study Aid

Hypothalamic-Pituitary Hormones
8 Picmonics to Learn | 18 mins
Ovulatory Hormones I - Follicular Phase
Characteristics
0-14 Days
GnRH Stimulates FSH and LH
Follicle Secretes Estrogen
Negative Feedback from Estrogen
Increased Estrogen Leads to Positive Feedback
FSH and LH Surge
LH Spike Leads to Ovulation
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2 mins
Ovulatory Hormones II - Luteal Phase
Days 15-28
Corpus Luteum
Secretes Progesterone
Negative Feedback inhibits FSH and LH
No pregnancy forms Corpus Albicans
Stops Estrogen Secretion
Endometrial Sloughing - Menses
GnRH secretion produces new follicular phase
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2 mins
Oxytocin (Pitocin)
Mechanism of Action
Increase Uterine Contractions
Indications
Labor Induction
Control Postpartum Hemorrhage
Side Effects
Uterine Rupture
Water Intoxication
Contraindications
Fetal Lung Immaturity
Cervix Not Ripened
Active Genital Herpes Infection
Considerations
Use Lowest Dose
IV Pump
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3 mins
Hypothalamus
Characteristics
Anterior Pituitary Stimulated Through the Hypophyseal Portal
GHRH
GnRH
TRH
PIF
CRF Released During Stress
Posterior Pituitary Stimulated Through Neural Control
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3 mins
Anterior Pituitary
Characteristics
Hypothalamic Control
FLAT PeG Mnemonic
Tropic Hormones
Follicle-Stimulating Hormone (FSH)
Lutenizing Hormone (LH)
Adrenocorticotropic Hormone (ACTH)
Thyroid-Stimulating Hormone (TSH)
Direct Hormones
Prolactin (PRL)
Growth Hormone (GH)
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2 mins
Posterior Pituitary
Characteristics
Neuroendocrine Reflex Stimulation (By Hypothalamus)
Direct Hormones
Vasopressin
Increased Water Retention (In Kidneys)
Oxytocin
Increased Uterine Contraction
Mammary Glands Contraction
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2 mins
Somatostatin
Secreted by D Cells
Pancreas
GI Tract
Action
Decrease Secretion of Gastric Acid and Pepsinogen
Decrease Pancreatic and Small Intestine Fluid Secretion
Decrease Gallbladder Contraction
Decrease Glucagon and Insulin Secretion
Regulation
Secretion is Increased by Acid
Secretion is Decreased by Vagal Stimulation
Clinical Use
Octreotide
Carcinoid Syndrome
Variceal Bleeds
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2 mins
Growth Hormone (GH)
Characteristics
Secreted by Anterior Pituitary
Growth of Bone, Muscle, and Tissue
Insulin-like Growth Factor 1 (IGF-1)
Increased Secretion
Hypoglycemia
Deep Sleep
Puberty
Exercise
Decreased Secretion
Glucose
Somatostatin
Clinical
Pituitary Adenoma
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3 mins

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