First Generation Antihistamines
- Histamine H1 Receptor Antagonist
- Allergies
- Nausea and Vomiting
- Motion Sickness
- Anaphylaxis
- Diphenhydramine (Benadryl)
- Promethazine (Phenergan)
- Chlorpheniramine
- Sedation
- Anticholinergic Effects
Second Generation Antihistamines
- Allergies
- Lipophobic
- Histamine H1 Receptor Antagonist
- Azelastine + Fluticasone (Dymista)
- Intranasal Spray
- Cetirizine (Zyrtec)
- Loratadine (Claritin)
- Fexofenadine (Allegra)
- Fewer Anticholinergic Effects
- Fewer CNS Effects
Prostacyclin Analogs
- Prostaglandin I2 (Prostacyclin)
- Vasodilation of Pulmonary and Systemic Arteries
- Inhibits Platelet Aggregation
- Pulmonary Hypertension
- Flushing
- Jaw Pain
- Epoprostenol
- Iloprost
- Treprostinil
Endothelin Receptor Antagonists
- Pulmonary Hypertension
- Competitive Antagonism of Endothelin Receptors
- Decreased Pulmonary Vascular Resistance
- Bosentan
- Hepatotoxicity
- Monitor LFTs
Dextromethorphan
- Codeine Analog
- Weak Opioid
- NMDA Receptor Antagonist
- Cough Suppressant
- Serotonin Syndrome
- Drug Overdose
- Naloxone