Ace Your First Aid for the USMLE Step 1 (2020) Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Medicine (MD/DO) Students
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First Aid for the USMLE Step 1 (2020) | Medicine (MD/DO) School Study Aid
Codon Overview
- Characteristics
- mRNA Read In Three Nucleotide Chunks
- AUG Is Start Codon
- Matching tRNA Anticodon
- Amino Acid Specific (To Codon)
- AUG Codes For Methionine
- UAA, UAG And UGA Are Termination Codons
2 mins
Transcription Overview
- Initiation
- RNA Polymerase Binds Promoter
- Elongation
- DNA Opens by Helicase
- RNA Polymerase Reads 3' to 5'
- Nucleotides Added to 3' End
- Termination
- Stem Loop Formation
- Rho Protein Factor
3 mins
Translation: Initiation
- Translation: Initiation
- Ribosome Binds mRNA
- Complex Reads 5' to 3'
- AUG Start Codon
- Initiation Complex Forms
- GTP and Initiation Factor Bring Complex Together
- Met-tRNA Binds P Site
- tRNA With Bound Amino Acids Binds A Site
- Amino Acid Chain Created in Elongation
3 mins
Translation: Elongation & Termination
- Translation: Elongation
- Amino Acid Chain Is Created
- New Amino Acid-tRNA Enters A Site
- GTP and Elongation Factors Help tRNA Enter A Site
- Peptide Chain Binds to New Amino Acid
- Peptide Chain-tRNA Moves to P Site
- Free tRNA in P Site Moves to E Site
- Translation: Termination
- Stop Codon at A Site Causes Termination
- Release Factors Help Complex Disassociate
- Complex Falls Apart
3 mins
Eukaryotic Post Transcriptional Modification
- Modifications in Nucleus
- mRNA Splicing
- Introns Cut Out
- Exons spliced together
- Alternate Splicing
- 5' Cap added
- 3' Poly A tail added
- Transported to Cytosol
2 mins
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