HLA-B27 Associations
- PAIR Acronym
- Psoriatic Arthritis
- Ankylosing Spondylitis
- Inflammatory Bowel Disease
- Reactive Arthritis
Cell Surface Proteins - B Cells
- Ig
- CD19
- CD20
- CD21
- CD40
- MHC II
- B7
Hemochromatosis Pathophysiology
- Hemosiderin Deposition
- Autosomal Recessive
- HLA-A3
- Secondary to Transfusion Therapy
- Increase Iron
- Increase Ferritin
- Increased Transferrin Saturation
Addison's Disease
- Chronic 1° Adrenal Insufficiency
- Atrophy
- Destruction
- Deficiency In Cortisol And Aldosterone
- Skin Hyperpigmentation
- Increased POMC
- Hypotension
- Hyperkalemia
- Acidosis
- Addisonian Crisis
- ACTH (Cosyntropin) Stimulation Test
- Exogenous Cortisol
Myasthenia Gravis
- Antibodies to Acetylcholine Receptor
- Ptosis
- Diplopia
- Weakness with Muscle Use
- Respiratory Death
- Thymus Associated
- Acetylcholinesterase Inhibitors
- Plasmapheresis
- Thymectomy
Graves' Disease Labs and Treatment
- Decreased TSH
- Increased T3
- Increased T4
- Radioactive Iodine Uptake (RAIU)
- Beta blocker
- Methimazole
- Radioiodine Ablation
Ankylosing Spondylitis
- Chronic Inflammatory Arthritis
- "Bamboo Spine"
- HLA-B27
- Uveitis
- Aortic Regurgitation
Psoriasis
- Epidermal Hyperproliferation Keratinocytes
- Defined Red Salmon Plaques
- Silvery Scales
- Extensor Surfaces
- Bleeding when Removed
- Auspitz Sign
- Pruritus
- Nail Changes
- Munro Microabscesses
- Nucleated Cells in Stratum Corneum
- Retinoids
- Topical Corticosteroids
- Tar
- Immunosuppressants
Celiac Disease Characteristics
- European Descent
- HLA-DQ2
- HLA-DQ8
- Autoimmune-mediated Intolerance of Gliadin
- Dermatitis Herpetiformis
- Weight Loss
- Failure to Thrive
- Decreased Bone Density
- Steatorrhea
- Anemia
Multiple Sclerosis Features and Mechanisms
- More Common in Women
- Presents in 20's and 30's
- Northern Europeans
- Unknown mechanism, genetic factor
- HLA-DRB1
- Autoimmune Demyelination of CNS
- White Matter of Brain and Spinal Cord
- T Cell Mediated Inflammation
Hashimoto's Thyroiditis
- Hypothyroidism with Bouts of Hyperthyroidism
- Enlarged, Nontender Thyroid
- Autoimmune
- Anti-Thyroid Peroxidase (TPO)
- Anti-Thyroglobulin
- Hurthle Cells
- Lymphoid Follicles
- HLA-DR5 and HLA-DR3
- Increased Risk Of Non-Hodgkin Lymphoma
Systemic Lupus Erythematosus (SLE) Mechanism, Treatment and Complications
- Systemic Autoimmune Disease
- 9:1 female to male ratio
- Glucocorticoids
- NSAIDS
- Hydroxychloroquine
- Cyclophosphamide
- Lupus nephritis
- Libman-Sacks Endocarditis
- Secondary Antiphospholipid Antibody Syndrome
- Drug-induced lupus
Rheumatoid Arthritis Assessment
- Destruction of Connective Tissue and Synovial Membrane
- Inflammation of Joints
- Morning Stiffness
- Nodules
- Joint Deformities