Nephritic Syndrome
- Inflammatory
- Hematuria
- RBC casts
- Increased Nitrogen in blood
- Oliguria
- Hypertension
- Proteinuria < 3.5 grams per day
Rapidly Progressive Glomerulonephritis
- Nephritic Syndrome
- Crescent Shape
- Crescents Consist of Fibrin and C3b
- With Parietal Cells, Monocytes, and Macrophages
- Linear Immunofluorescence
- Negative Immunofluorescence
- Granular Immunofluorescence
- Goodpasture Syndrome
- Granulomatosis with Polyangiitis (Formerly Wegener's)
- Microscopic Polyangiitis
- Poor Prognosis
Post Streptococcal Glomerulonephritis
- Nephritic
- Children
- Edema
- Cola Colored Urine
- Follows Group A Streptococcal pharyngitis or Skin Infection
- Neutrophils
- Immunofluorescence (IF) Granular
- Lumpy Bumpy Appearance on Immunofluorescence (IF)
- Subepithelial Immune Complex Humps
Granulomatosis with Polyangiitis (GPA) Characteristics
- Small Vessel Vasculitis
- Necrotizing
- Lungs and Upper Airway
- Crescentic Glomerulonephritis
- c-ANCA
- X-ray
- Multiple Nodules in Lungs
- Cyclophosphamide
- Corticosteroids
- Rituximab
Granulomatosis with Polyangiitis (GPA) Symptoms
- Saddle Nose
- Perforation of Nasal Septum
- Chronic Sinusitis
- Otitis Media
- Mastoiditis
- Cough
- Dyspnea
- Hemoptysis
- Rapidly Progressive Glomerulonephritis
- Hematuria
- RBC Casts
Anti-glomerular Basement Membrane Antibodies
- Glomerulonephritis
- Goodpasture's Disease
- Linear immunofluorescence
- Hemoptysis
- Hematuria
Berger's Disease (IgA Nephropathy)
- Nephritic
- IgA Nephropathy
- Immune Complex Deposit in Mesangium
- Increased Synthesis of IgA
- Most Common Cause of Nephritic Syndrome
- Overlapping Features with Henoch–Schönlein Purpura
- Presents with Pharyngitis, URI or Acute Gastroenteritis
Alport Syndrome
- Nephritic
- X-linked
- Mutation in Type IV Collagen
- Split Basement Membrane
- Basket Weave Appearance
- Ocular Disorders
- Deafness
Membranoproliferative Glomerulonephritis
- Nephritic-Nephrotic Syndrome
- Type I
- Subendothelial Immune Complexes
- Hepatitis C Virus
- Granular IF
- Tram Tracks Caused by Splitting of the GBM
- Ingrowth of Mesangium
- Type II
- Dense Deposit Disease
- C3 Nephritic Factor
Diffuse Proliferative Glomerulonephritis (DPGN)
- Nephritic and Nephrotic Syndrome
- Systemic Lupus Erythematosus (SLE)
- IgA Nephropathy
- Wire Looping
- IF Granular
- Subendothelial Immune Complexes
- Subepithelial Immune Complexes
- C3 Deposition
- Treat Underlying Disorder
- Steroids