Selective Serotonin Reuptake Inhibitor (SSRI) Overview
- Depression
- Anxiety
- Selective Serotonin Reuptake Inhibitors
- Paroxetine
- Sertraline
- Escitalopram
- Fluoxetine
- Sexual Dysfunction
- Serotonin Syndrome
- Treat with Cyproheptadine
Fluoxetine (Prozac)
- Inhibits Reuptake of Serotonin
- Depression
- Sexual Dysfunction
- CNS Stimulation
- Weight Changes
- Serotonin Syndrome
- No MAO-Is
- No Anticoagulants / Antiplatelets
- Suicide Risk
- Delayed Onset of Action
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
- Depression
- Diabetic Peripheral Neuropathy
- Duloxetine
- Panic and Anxiety
- Venlafaxine
- Inhibits Reuptake of Serotonin and NE
- Hypertension
- Insomnia
- Nausea and Vomiting
- Decreased Libido
Tricyclic Antidepressants (TCAs) Overview
- Blocks Serotonin and NE Reuptake
- Lipid-soluble
- Adverse CNS Effects
- Anticholinergic
- Antihistamine
- Tri-C: Convulsion, Coma, Cardiotoxicity
- Blocks Alpha1 Receptors
Tricyclic Antidepressants (TCAs) Indications
- Major Depression
- Bedwetting
- Fibromyalgia
- OCD
- -Iptyline or -Ipramine Suffix
- Amitriptyline
- Desipramine
- Clomipramine
- Imipramine
- Nortriptyline
Tricyclic Antidepressant (TCA) Antidote
- Sodium Bicarbonate (NaHCO3)
Monoamine Oxidase Inhibitors (MAO-Is)
- Atypical Depression
- Increase Levels of Amine Neurotransmitters
- "Takes Pride In Shanghai"
- Tranylcypromine
- Phenelzine
- Isocarboxazid
- Selegiline
Monoamine Oxidase Inhibitor (MAOI) Contraindications
- Wine and Cheese
- Hypertensive Crisis
- Serotonin Drugs
- Serotonin Syndrome
Malignant Hyperthermia vs. Neuroleptic Malignant Syndrome vs. Serotonin Syndrome
- Autonomic Instability
- Muscle Rigidity
- Ryanodine Receptor 1 Mutation
- Inhaled Anesthetics
- Succinylcholine
- Dantrolene
- Antidopaminergic Medications
- Hyporeflexia
- Myoglobinuria
- Dantrolene
- Serotonergic Medications
- Hyperreflexia
- Clonus
- Cyproheptadine