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Medicine (MD/DO)
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First Aid
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First Aid for the USMLE Step 1 (2022)
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First Aid for the USMLE Step 1 (2022) | Medicine (MD/DO) School Study Aid

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6 Picmonics to Learn | 15 mins
Blood Types
Allele A is Dominant
Allele B is Dominant
Allele O is Recessive
Genotypes AA and AO have Type A Blood
Genotypes BB and BO have Type B Blood
Genotype AB is co-dominant and has Type AB Blood
Genotype OO Results in Type O Blood
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2 mins
Blood Types and Compatibilities
ABO Compatibility
No Antigens (Type O Blood)
Universal Donor
A Antigen (Type A Blood)
B Antigen (Type B Blood)
AB Antigen (Type AB Blood)
Universal Recipient
Rhesus (Rh) Compatibility
Rh (Rhesus) Antigen
Never Rh+ to Rh-
Considerations
Blood Transfusion
Obstetric Patient
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2 mins
Whole Blood Composition
Characteristics
Plasma
Electrolytes And Other Solutes
Proteins
Albumin
Fibrinogen
Globulins
Water
Formed Elements
Buffy Coat
White Blood Cells (WBC)
Platelets
Red Blood Cells (RBC)
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2 mins
Rh Hemolytic Disease of the Fetus and Newborn
Characteristics
Rh (Rhesus) Incompatibilities
Rh(D)- Mother and Rh(D)+ Fetus
Anti-Rh(D) Antibodies
Hemolytic Anemia
Presentation
Hydrops Fetalis
Neonatal Jaundice
Kernicterus
Diagnosis
Positive Coombs Test
Ultrasound
Management
RhoGAM [Anti-Rh(D) Immunoglobulin]
Intrauterine Blood Transfusion
Phototherapy
IVIG (Intravenous Immunoglobulin)
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4 mins
ABO Hemolytic Disease of the Fetus and Newborn
Characteristics
ABO Incompatibilities
Type O Mother and Type A/B Fetus
Anti-A or Anti-B Antibodies
Hemolytic Anemia
Presentation
Often Asymptomatic
Neonatal Jaundice
Diagnosis
Negative Coombs Test
Management
Phototherapy
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2 mins
RhoGam [Rho(D) Immune Globulin]
Indications
Antepartum Prevention at 28 weeks
Suppress Antibody Production
Mechanism of Action
Lysis of Fetal RBC in Maternal Bloodstream
Side Effects
Myalgia and Lethargy
Considerations
Negative Coombs Test
Standard Dose 300 mcg
Microdose 50 mcg
Blood Product
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2 mins

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