Multiple Myeloma Pathophysiology
- Monoclonal Plasma Cell Cancer
- Clock Face Chromatin
- M Spike on Protein Electrophoresis
- Increased IgG and IgA
- Fried Egg Appearance (BM Biopsy)
- Rouleaux Formation
- Stacked RBC's
- Bence Jones Protein
Multiple Myeloma Signs and Symptoms
- Increased Susceptibility to Infection
- Back/Bone Pain
- Punched Out Lytic Bone Lesions
- Hypercalcemia
- Primary Amyloidosis
- Renal Insufficiency
- Anemia
Waldenstrom Macroglobulinemia
- Non-Hodgkin Lymphoma
- Peripheral Neuropathy
- Hyperviscosity Syndrome
- Headache, Blurred Vision
- Raynaud Phenomenon
- Thrombosis
- Petechiae
- Abnormal Plasma Cells
- Dutcher Bodies
- Monoclonal IgM Antibodies
- Observation
- Chemotherapy
- Plasmapheresis
Myelodysplastic Syndromes
- Dysfunctional Bone Marrow
- Elderly
- Radiation or Chemotherapy
- Anemia
- Increased Susceptibility to Infection
- Bleeding
- Ringed Sideroblasts
- Howell-Jolly Bodies
- Pseudo-Pelger-Huet Anomaly
- Bilobed Neutrophils
- Supportive Care
- Bone Marrow Transplant
- Acute Myelogenous Leukemia (AML)