Basal Cell Carcinoma of the Skin
- Most Common Skin Cancer
- 2/3 of Cases Due to UV Light Exposure
- Pink, Pearl-like Lesions
- Rolled Borders
- Telangiectasias
- Commonly Upper Lip
- Shave Biopsy
- Pallisading Nuclei
- Mohs Micrographic Surgery
Squamous Cell Carcinoma of the Skin
- 2nd Most Common Skin Cancer
- UV Light Exposure
- Long-term Immunosuppression
- Arsenic Exposure
- Ulcerative Red Lesion
- Precursor Actinic Keratosis
- Commonly Lower Lip
- Biopsy shows Keratin Pearls
- Mohs Micrographic Surgery
Keratoacanthoma
- Low-Grade Skin Tumor
- Dome-shaped Nodule with Central Crater
- More Common in Elderly
- Sun-exposed Skin
- Resembles Squamous Cell Carcinoma of the Skin
- Grows Rapidly over 4-6 Weeks
- Wide Excisional Biopsy
- Mohs Micrographic Surgery
Types of Malignant Melanoma
- Superficial Spreading
- Most Common Cause of Melanoma
- Nodular
- Aggressive and Rapidly Arising
- Acral-Lentiginous
- Males
- Asians and African Americans
- Lentigo Maligna
- Geographic Shape
- Sun Exposed Areas
ABCDEs of Melanoma
- Asymmetry
- Border
- Color
- Diameter
- Evolving
Melanoma Mechanism and Characteristics
- Associated with Sunlight Exposure
- Mutation in B-RAF kinase
- Large Number of Moles
- Fair-Skinned People at Higher Risk
- Radial Growth Phase
- No Metastasis
- Vertical Growth Phase
- Depth of Tumor Correlates with Risk of Metastasis
Melanoma Diagnosis
- ABCDE Mnemonic
- Asymmetry
- Border irregularity
- Color variation
- Diameter > 6mm
- Evolution over time
- S-100 Tumor Marker
- LDH (Lactate Dehydrogenase) Screens for Metastasis
- Wide Local Excision
- Adjuvant Therapy