Baclofen
- GABA-B Receptor Agonist
- Spinal Cord
- Spasticity
- Dystonia
- Multiple Sclerosis
- CNS Depression
- Nausea
- Taper Gradually
Cyclobenzaprine (Flexeril)
- Centrally-Acting Muscle Relaxer
- Act on Alpha and Gamma Motor Neurons
- Related to Tricyclic Antidepressants (TCAs)
- Muscle Spasms
- Back Pain
- MAO Inhibitors
- Serotonin Syndrome
- Drowsiness
- Arrhythmia
Malignant Hyperthermia vs. Neuroleptic Malignant Syndrome vs. Serotonin Syndrome
- Autonomic Instability
- Muscle Rigidity
- Ryanodine Receptor 1 Mutation
- Inhaled Anesthetics
- Succinylcholine
- Dantrolene
- Antidopaminergic Medications
- Hyporeflexia
- Myoglobinuria
- Dantrolene
- Serotonergic Medications
- Hyperreflexia
- Clonus
- Cyproheptadine
Opioids Overview
- Pain
- Weaning
- Cough
- Diarrhea
- Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
- Decrease Synaptic Transmission
- Respiratory Depression
- Addiction
- Miosis
- Constipation
Naloxone (Narcan)
- Competitive Opioid Receptor Antagonist
- Opioid Induced CNS Depression
- Severe Nausea and Vomiting
- Excitable State
- Opioid Withdrawal Symptoms
- Repeated Dosing Often Required
Opioid Use Disorder and Withdrawal Assessment (Formerly Opioid Abuse and Withdrawal Assessment)
- Euphoria
- Miosis
- CNS Depression
- Yawning
- Gooseflesh
- Sweating
- Rhinorrhea
- Kicking Movements
- Naloxone
Buprenorphine-Naloxone (Suboxone)
- Combination Drug
- Partial Opioid Receptor Agonist (Buprenorphine)
- Opioid Receptor Antagonist (Naloxone)
- Opioid Use Disorder
- CNS Depression
- Diaphoresis
- Hypotension
- Low Abuse Potential
Codeine
- Opioid Receptor Agonist
- Mild to Moderate Pain
- Cough Suppressant
- Sedation
- Constipation
- Miosis
- Close Monitoring When Breast Feeding
- Often Combined with Non-Opioids
Oxycodone
- Opioid Receptor Agonist
- Refractory Pain
- Respiratory Depression
- Constipation
- CNS Depression
- Addiction
- Naloxone
Fentanyl
- Opioid Receptor Agonist
- High Potency
- Anesthesia Induction
- Chronic Pain
- Breakthrough Pain
- CNS Depression
- Respiratory Depression
- Constipation
- Miosis
- Addiction
Morphine
- Opioid Receptor Agonist
- Pain
- Myocardial Infarction
- Nausea and Vomiting
- CNS Depression
- Biliary Colic
- Constipation
- Increased Intracranial Pressure (ICP)
- Pupillary Constriction
- Hypotension
Meperidine (Demerol)
- Opioid Receptor Agonist
- Moderate to Severe Pain
- Post Anesthesia Shivering
- Tremors
- Constipation
- CNS Depression
- Sedation
- Short Term Administration
- Increased Risk Serotonin Syndrome
- Does NOT cause Miosis
- Renal Failure Increases Toxicity Risk
Alcohol Use Disorder Interventions (Formerly Alcohol Abuse Interventions)
- Reduce Environmental Stimuli
- Antianxiety Medications
- Vitamin Supplements
- Seizure Precautions
- Suicide Precautions
- Fever
- Identify Support Systems
- Group Therapy
- Disulfiram
- Naltrexone
Tramadol
- Chronic Pain
- Weak Opioid
- Inhibit Serotonin and NE reuptake
- Increased Risk of Seizure