Steroid Hormones
- Nuclear Membrane
- Long-Lived and Slow-Acting
- Cholesterol-Derived
- Intracellular Receptors
- DNA Transcription
- Testosterone
- Aldosterone
- Estrogen
- Cortisol
17 Alpha Hydroxylase Deficiency
- Decreased Cortisol
- Decreased Sex Hormones
- Increased Mineralocorticoids (DOC)
- Hypertension
- Hypokalemia
- XY Externally Phenotypic Female
- No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
- XX Externally Phenotypic Female
- Sexual Infantilism
21 Hydroxylase Deficiency
- Decreased Cortisol
- Increased 17 Hydroxyprogesterone
- Decreased Aldosterone
- Hypotension
- Increased Renin
- Hyperkalemia
- Female Pseudohermaphroditism
11 Beta-Hydroxylase Deficiency
- Decreased Cortisol
- Decreased Aldosterone
- Increased Sex Hormones
- Increased 11 Deoxycorticosterone (11 DOC)
- Hypertension
- Masculinization
Aromatase Inhibitors
- Estrogen Receptor-positive (ER+) Breast Tumors
- Systemic Metastases
- Reversible, non-steroid
- Letrozole
- Anastrozole
- Irreversible, steroid
- Exemestane
- Osteoporosis
- Arthritis
Peripheral Precocious Puberty
- Secondary Sex Characteristics before 8 Years (Girls) or 9 Years (Boys)
- Breast Development (Girls) or Testicular Enlargement (Boys)
- GnRH Independent
- Congenital Adrenal Hyperplasia
- Exogenous Sex Steroids
- Granulosa Cell Tumor
- Non-Germ Cell Tumor
- GnRH Stimulation Test
- No Increase in LH
- Bone Age
- Hormone Levels
- Treating Underlying Disorders