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Medicine (MD/DO)
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First Aid
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First Aid for the USMLE Step 1 (2024)
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First Aid for the USMLE Step 1 (2024) | Medicine (MD/DO) School Study Aid

Page 324 -
9 Picmonics to Learn | 16 mins
Nitroglycerin
Indications
Pulmonary Edema
Angina
Mechanism of Action
Decreases Preload
Releases NO in Blood
Side Effects
Hypotension
Reflex Tachycardia
Flushing
Monday Disease
Contraindications
Viagra (Sildenafil)
picmonic thumbnail
2 mins
Cardiovascular Effects of Beta-Blockers
Cardiac Myocytes and Vasculature
Decrease cAMP
Decreases SA and AV Node Conduction Velocity
Lower Blood Pressure
Decrease O2 Consumption
Decreases Mortality Post-MI
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2 mins
Ranolazine
Mechanism
Inhibits Late Sodium Current
No Effect on Heart Rate or Blood Pressure
Prevents Calcium Overload
Indication
Refractory Angina
Side Effects
Dizziness
Headache
Nausea
Constipation
QT Interval Prolongation
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1 min
Hypercholesterolemia Treatment
Lifestyle Modifications (Diet, Exercise, Smoking Cessation)
Statins
Niacin
Ezetimibe
Fibrates
Bile Acid Resins
PCSK9 Inhibitors
Omega 3 Fatty Acids
Screening
Pooled Cohort Test
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2 mins
Statins
Rhabdomyolysis
Hepatotoxicity
HMG-CoA reductase inhibitors
Decrease LDL
Decrease Triglycerides
Increase HDL
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2 mins
Atorvastatin (Lipitor)
Characteristics
-statin Suffix
Mechanism
HMG-CoA Reductase Inhibitors
Indications
High Cholesterol
Side Effects
Hepatotoxicity
Rash
Rhabdomyolysis
Myopathy
Considerations
Monitor Liver Enzymes
Administer at Bedtime
Avoid Grapefruit
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2 mins
Bile Acid Resins
Indications
Hyperlipidemia
Mechanism of Action
Bile Acid Reabsorption Prevented
Slight Increase HDL/Triglycerides
Decrease LDL
Drugs
Colestipol (Colestid)
Cholestyramine
Colesevelam
Side Effects
Cholesterol Gallstones
Decreased Absorption of Fat-soluble Vitamins
Patients Hate It
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2 mins
Ezetimibe
Indications
Hyperlipidemia
Mechanism of Action
Cholesterol Absorption Blocker
Decreases LDL
Side Effects
Diarrhea
Increased LFT Values
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1 min
Sacubitril
Indication
Heart Failure
Mechanism
Neprilysin Inhibitor
Side Effects
Combine With Valsartan
Hypotension
Hyperkalemia
Cough
Dizziness
Contraindication
Avoid With Ace Inhibitors
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2 mins

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