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First Aid
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First Aid for the USMLE Step 1 (2024)
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First Aid for the USMLE Step 1 (2024) | Medicine (MD/DO) School Study Aid

Page 360 -
7 Picmonics to Learn | 12 mins
Propylthiouracil (PTU) and Methimazole (MMI)
Indications
Hyperthyroidism
Mechanism
Inhibits Thyroid Peroxidase
PTU Blocks Peripheral Conversion of T4 to T3
Side Effects
Agranulocytosis
Skin Rash
Hepatotoxicity (PTU)
Teratogen (MMI)
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1 min
Levothyroxine
Indications
Hypothyroidism
Myxedema Coma
Mechanism of Action
Isomer of Thyroid Hormone (T4)
T3 has Higher Potency
Side Effects
Hyperthyroid Symptoms
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57 secs
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Pharmacologic Interventions
Diuretics
Hypertonic IV Fluids
Demeclocycline
Tolvaptan and Conivaptan
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1 min
Oxytocin (Pitocin)
Mechanism of Action
Increase Uterine Contractions
Indications
Labor Induction
Control Postpartum Hemorrhage
Side Effects
Uterine Rupture
Water Intoxication
Contraindications
Fetal Lung Immaturity
Cervix Not Ripened
Active Genital Herpes Infection
Considerations
Use Lowest Dose
IV Pump
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3 mins
Somatostatin
Secreted by D Cells
Pancreas
GI Tract
Action
Decrease Secretion of Gastric Acid and Pepsinogen
Decrease Pancreatic and Small Intestine Fluid Secretion
Decrease Gallbladder Contraction
Decrease Glucagon and Insulin Secretion
Regulation
Secretion is Increased by Acid
Secretion is Decreased by Vagal Stimulation
Clinical Use
Octreotide
Carcinoid Syndrome
Variceal Bleeds
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2 mins
Octreotide
Indications
Acute Variceal Bleeds
Pituitary Tumors
GH Secreting Tumors
Carcinoid Tumors
VIPoma
Mechanism
Somatostatin Analog
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2 mins
Fludrocortisone
Mechanism of Action
Aldosterone Analog
Indications
Addison’s Disease (Primary Adrenal Insufficiency)
Congenital Adrenal Hyperplasia
Side Effects
Cushing Syndrome
Edema
Congestive Heart Failure Exacerbation
Hyperpigmentation
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2 mins

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