Selective Serotonin Reuptake Inhibitor (SSRI) Overview
- Depression
- Anxiety
- Selective Serotonin Reuptake Inhibitors
- Paroxetine
- Sertraline
- Escitalopram
- Fluoxetine
- Sexual Dysfunction
- Serotonin Syndrome
- Treat with Cyproheptadine
Succinylcholine
- Inducing Paralysis
- Neuromuscular Blocking Drugs
- Motor Nicotinic Receptor
- ACh Receptor Agonist
- Depolarization
- Phase I (Paralysis Non-reversible)
- Phase II (Paralysis Reversible)
- Neostigmine (Reversal Agent)
Tetracycline Toxicities
- Inhibition of Bone Growth in Children
- Teratogen
- Discoloration of Teeth
- Photosensitivity
- GI Distress
Valproic Acid
- First Line Tonic-Clonic Seizure Treatment
- Bipolar Disorder
- Migraine Prophylaxis
- Increases GABA Concentration
- Blocks Voltage-Gated Na+ Channels
- GI Distress
- Contraindicated in Pregnancy
Vancomycin Mechanism
- Bacteriostatic and Bactericidal
- Gram-Positive
- Inhibits Cell Wall Mucopeptide
- Binds to D-ala D-ala
- Resistance with Change to D-ala D-lac
- Staphylococcus aureus
- Orally for Clostridium difficile
- Enterococci
Vancomycin Side Effects & Toxicity
- Thrombophlebitis
- Nephrotoxicity
- Ototoxicity
- Diffuse Flushing Called Red Man Syndrome
- Prevent with Antihistamine
- Prevent with Slow Infusion
Vincristine (Oncovin)
- Vinca Alkaloid
- Inhibits Microtubules
- Leukemias
- Lymphomas
- Peripheral Neuropathy
- Paralytic Ileus
- Vesicant
Propylthiouracil (PTU) and Methimazole (MMI)
- Hyperthyroidism
- Inhibits Thyroid Peroxidase
- PTU Blocks Peripheral Conversion of T4 to T3
- Agranulocytosis
- Skin Rash
- Hepatotoxicity (PTU)
- Teratogen (MMI)