Ace Your Pathoma: Fundamentals of Pathology (2018) Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Medicine (MD/DO) Students
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Pathoma: Fundamentals of Pathology (2018) | Medicine (MD/DO) School Study Aid
Achondroplasia
- Mechanism
- Autosomal Dominant
- Advanced Paternal Age
- Most Common Cause of Dwarfism
- Mutation of FGFR3 (Fibroblast Growth Factor Receptor 3)
- Defective Endochondral Ossification
- Symptoms
- Delayed Motor Milestones
- Shortened Limbs with Normal Axial Skeleton Size
- May Develop Hydrocephalus
- Symptoms of Spinal Stenosis
- Normal Life Span and Fertility
2 mins
Osteogenesis Imperfecta
- Pathophysiology
- Autosomal Dominant
- Decreased Type I Collagen Production
- Symptoms
- Phenotypically Diverse
- Brittle Bone Disease
- Fractures from Minimal Trauma
- Confused with Child Abuse
- Hearing Loss
- Dental Imperfections
- Blue Sclera
1 min
Osteopetrosis (Marble Bone Disease)
- Pathophysiology
- Defective Osteoclast Resorption
- Carbonic Anhydrase II Mutation
- Lack of Acidic Environment
- Symptoms
- Fractures
- Nerve Palsies
- Diagnosis
- Myelophthisic Anemia
- Erlenmeyer Flask Bones
- Normal ALP and PTH
- Normal Calcium and Phosphorus
- Bone-in-bone Appearance
- Treatment
- Bone Marrow Transplant
2 mins
Vitamin D Deficiency
- Signs & Symptoms
- Rickets in children
- Bending bones
- Rachitic rosary
- Breast milk has decreased vitamin D
- Osteomalacia in adults
- Tetany from Hypocalcemia
2 mins
Osteoporosis Assessment
- Highest Risk
- Postmenopausal Women
- Long Term Corticosteroids
- Assessment
- Kyphosis
- Dowager's Hump
- Loss of Height
- Back Pain
- Pathologic Fractures
- Spinal Compression Fracture
1 min
Osteoporosis Interventions
- Increased Calcium Intake
- Vitamin D Supplements
- Bisphosphonates
- Raloxifene
- Denosumab
- Calcitonin
- Teriparatide
- Bone Densitometry (DEXA) Scan
- Weight Bearing Exercises
2 mins
Paget's Disease of Bone
- Pathophysiology
- Men > Age 40
- Increased Osteoblast and Osteoclast activity
- Mosaic Pattern
- Signs and Symptoms
- Increased Skull Diameter
- Hearing Loss
- Fractures
- Bone Ache and Joint Pain
- High Output Heart Failure
- Diagnosis
- Bone Scan
- Normal Parathyroid hormone (PTH) and Calcium
- Elevated ALP
- Treatment
- Bisphosphonate
- Calcitonin
2 mins
Osteomyelitis
- Cause/Mechanism
- Bone Infection
- Assessment
- Warmth
- Edema
- Constant Bone Pain
- Fever
- Interventions
- IV Antibiotics
- Implanted Beads
- Hyperbaric Oxygen
- Surgical Removal of Ischemic Tissue
- Considerations
- Elevated ESR
3 mins
Hip Fracture
- Assessment
- External Rotation
- Muscle Spasms
- Shortened Leg
- Pain
- Interventions
- Buck's Traction
- Analgesics
- Surgery
- Considerations
- Avascular Necrosis
1 min
Legg-Calve-Perthes Disease
- Pathophysiology
- Idiopathic Avascular Necrosis of Femoral Head
- Boys 5-7 Years of Age
- Symptoms < 18 Months
- Signs & Symptoms
- Painless Limp
- Limited Range of Motion
- Intermittent Anterior Thigh Pain
- Insidious Pain in Knee
- Atrophy of Upper Thigh
- Diagnosis
- AP and Frog Leg Lateral X-ray
- Compression and Deformity of Femoral Head
- Treatment
- Bed Rest
- NSAIDs
- Containment with Brace or Cast
- Surgery
4 mins
Slipped Capital Femoral Epiphysis (SCFE)
- Pathophysiology
- Separation of Femoral Epiphysis from Femoral Neck
- Through Growth Plate (Physeal Plate)
- Obesity
- Male Adolescents
- African American
- Growth and Sex Hormone Imbalances
- Signs & Symptoms
- Thigh or Knee Pain
- Inability to Bear Weight
- Decreased Internal Rotation of Hip
- Obligate External Rotation of Hip with Flexion
- Diagnosis
- Frog Leg Lateral X-ray
- Treatment
- Surgical Pinning
- Complications
- Avascular Necrosis of Femoral Head
3 mins
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