Nurse Practitioner Certification Examination and Practice Preparation 4th Edition, Fitzgerald, 2015 | Nurse Practitioner (NP) School Study Aid
Diabetes Assessment
- Juvenile Onset
- Absent Insulin Production
- Ketosis Prone
- Adult Onset
- Insulin Resistance
- Obesity
- Onset During Pregnancy
- Glucose Intolerance
- Retinopathy
- Peripheral Vascular Disease
- Nephropathy
- Neuropathy
Diabetes Interventions
- Early Diagnosis
- Insulin
- Oral Hypoglycemics
- Glucose Monitoring
- Routine Exercise
- Diabetic Diet
- Monitor for Complications
- Insulin Therapy
- Diabetic Ketoacidosis (DKA)
Diabetes Education
- Self-Monitoring (Blood Glucose)
- SubQ Injection Technique
- Lifestyle Changes
- Symptoms of Hyperglycemia and Hypoglycemia
- Sick Day Care
- Foot Care
- Exercise Therapy
- Medication
Insulin
- Rapid Acting
- Insulin Lispro (Humalog)
- Insulin Aspart (Novolog)
- Insulin Glulisine (Apidra)
- Short Acting
- Regular Insulin (Humulin R)
- Intermediate Acting
- Isophane NPH (Humulin N)
- Long Acting
- Detemir (Levemir)
- Glargine (Lantus)
Oral Glucose Tolerance Test (OGTT)
- Used for Diabetes Screening
- Fasting State
- Baseline
- Normal < 100 mg/dL
- 30 and 60 Minutes
- Normal < 200 mg/dL
- 120 Minutes
- Normal < 140 mg/dL
Clopidogrel (Plavix)
- ADP Receptor Antagonist
- Prevent Platelet Aggregation
- Acute Coronary Syndrome (ACS)
- Prevention of Thrombotic Events
- Bleeding
- Thrombotic Thrombocytopenic Purpura (TTP)
- Pancytopenia
- Abdominal Pain
- Withhold Before Surgery
Glyburide and Glipizide (2nd Generation Sulfonylureas)
- 2nd Generation Sulfonylureas
- Blocks Potassium Channels in Beta Cells
- Stimulate Release of Insulin
- Type 2 Diabetes
- Hypoglycemia
- More Potent
- Beta Blockers Reduce Effects
- Avoid Alcohol
- Avoid Breastfeeding
Glucagon (GlucaGen)
- Increases Glucose
- Hypoglycemic Emergency
- Nausea and Vomiting
- Reconstitute Powder
- Consume Oral Carbohydrates
- 50% Dextrose IV (If No Effect)
Metformin
- Diabetes Mellitus Type 2
- Polycystic Ovary Syndrome (PCOS)
- Decreased Gluconeogenesis
- Increased Insulin Sensitivity
- Lactic Acidosis
- GI Distress
- Weight Loss
- B12 Deficiency
- GFR < 30 ml/min
Sitagliptin (Januvia) and Saxagliptin (Onglyza) (DPP-4 Inhibitors)
- -gliptin Suffix
- DPP-4 Inhibitor
- Increases Insulin Release
- Type 2 Diabetes
- Pancreatitis
- Upper Respiratory Infection and Inflammation
- Stevens-Johnson Syndrome
- Used as Add-on Agents
Acarbose (Precose) and Miglitol (Glyset) (Alpha Glucosidase Inhibitors)
- Alpha Glucosidase Inhibitors
- Delays Absorption of Carbohydrates
- Type 2 Diabetes
- Flatulence
- Diarrhea
- Anemia
- Cramps
- Monitor LFTs
- Oral Glucose for Hypoglycemia
Dawn Phenomenon
- Increased Hormone Production
- Hyperglycemia Upon Awakening
- Long-Acting Evening Insulin
- Change Administration Times
- Insulin Pump
- Closely Monitor Glucose Levels
- Between 2-6AM
- Limit Carbohydrates Before Bedtime
Angiotensin Receptor Blockers (ARBs)
- -sartan suffix
- Hypertension
- CHF
- Diabetic Nephropathy
- Angiotensin II Receptor Blockers
- Hyperkalemia
- Pregnancy
Calcium Channel Blockers (Verapamil and Diltiazem)
- Slows AV Conduction
- Angina Pectoris
- Arrhythmias
- Essential Hypertension
- Bradycardia
- Hypotension
- Constipation
- Peripheral Edema
- Gingival Hyperplasia
- Medication Education
Metabolic Syndrome
- Dyslipidemia
- Central Obesity
- Insulin Resistance
- Hypertension
- Increased C-Reactive Protein (CRP)
- Increased Fibrinogen
- Increased Risk Cardiovascular Disease
Prednisone (Glucocorticoids)
- Glucocorticoid
- Inflammatory Conditions
- Organ Transplant Rejection
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Adrenal Insufficiency
- Taper Gradually
Risperidone (Risperdal)
- Atypical Antipsychotic
- Schizophrenia
- Bipolar Mania
- Autism-Associated Irritability
- Extrapyramidal Symptoms
- Hyperprolactinemia
- Gynecomastia
- Galactorrhea
- Amenorrhea
- Prolonged QT
- Intramuscular Long Acting (Depot) Form
Carbamazepine
- First-line Seizure Medication
- First Line for Trigeminal Neuralgia
- Stabilizes Inactive State of Na+ Channels
- Stevens-Johnson Syndrome
- Induce Cytochrome P450
- Teratogen
- Hepatotoxicity
- Blood Dyscrasias
Valproic Acid
- First Line Tonic-Clonic Seizure Treatment
- Bipolar Disorder
- Migraine Prophylaxis
- Increases GABA Concentration
- Blocks Voltage-Gated Na+ Channels
- GI Distress
- Contraindicated in Pregnancy
Valproic Acid (Valproate) Side Effects
- Vomiting
- Alopecia
- Liver Toxicity
- Pancreatitis/Pancytopenia
- Retain Fat (Weight Gain)
- Oedema (Edema)
- Appetite Increase
- Tremor
- Enzyme Inhibitor (P450)
Hyperthyroidism Assessment
- Heat Intolerance
- Exophthalmos
- Warm, Moist Skin and Silky Hair
- Tremors
- Goiter
- Diarrhea
- Weight Loss
- Tachycardia
- Hypertension
- Amenorrhea
- Decreased TSH with Elevated Free T4
- Radioactive Iodine Uptake (RAIU)
Hyperthyroidism Interventions
- Propylthiouracil (PTU)
- Methimazole (Tapazole)
- Iodine
- Beta Blockers
- Radioiodine Ablation
- Thyroidectomy
- Thyrotoxicosis
- Post-Surgery Hypocalcemia
Hypothyroidism Assessment
- Weight Gain - Edema
- Lethargy
- Cold Intolerance
- Bradycardia
- Hypertension
- Brittle Nails and Dry Skin
- Constipation
- Goiter
- Prolonged Menses
- Slowed Thinking
- Decreased Free T4
- Increased TSH
Hypothyroidism Intervention
- Levothyroxine (Synthroid)
- Liothyronine (Cytomel)
- Myxedema Coma
- Lifelong Replacement Hormone
- Monitor Vital Signs
- Fluids and Fiber
- Low Calorie, Low Fat Diet
- Medication Education
- No Switching Brands
Hashimoto's Thyroiditis
- Hypothyroidism with Bouts of Hyperthyroidism
- Enlarged, Nontender Thyroid
- Autoimmune
- Anti-Thyroid Peroxidase (TPO)
- Anti-Thyroglobulin
- Hurthle Cells
- Lymphoid Follicles
- HLA-DR5 and HLA-DR3
- Increased Risk Of Non-Hodgkin Lymphoma
Levothyroxine
- Hypothyroidism
- Myxedema Coma
- Isomer of Thyroid Hormone (T4)
- T3 has Higher Potency
- Hyperthyroid Symptoms
Ezetimibe
- Hyperlipidemia
- Cholesterol Absorption Blocker
- Decreases LDL
- Diarrhea
- Increased LFT Values
Atorvastatin (Lipitor)
- -statin Suffix
- HMG-CoA Reductase Inhibitors
- High Cholesterol
- Hepatotoxicity
- Rash
- Rhabdomyolysis
- Myopathy
- Monitor Liver Enzymes
- Administer at Bedtime
- Avoid Grapefruit
Addison's Disease
- Chronic 1° Adrenal Insufficiency
- Atrophy
- Destruction
- Deficiency In Cortisol And Aldosterone
- Skin Hyperpigmentation
- Increased POMC
- Hypotension
- Hyperkalemia
- Acidosis
- Addisonian Crisis
- ACTH (Cosyntropin) Stimulation Test
- Exogenous Cortisol
Addisonian Crisis
- Severe Symptoms
- Shock
- High-Dose Hydrocortisone
- Large Volumes of IV Fluid
- Insulin with Dextrose
- Kayexalate
- Loop or Thiazide Diuretics
Cushing's Syndrome Symptoms And Diagnosis
- Osteoporosis
- Amenorrhea
- Truncal Obesity
- Skin Changes
- Buffalo Hump
- Immune Suppression
- Moon Facies
- Hypertension
- Decreased Insulin Sensitivity
- 24-hour urine free Cortisol
- Dexamethasone Suppression Test
Cushing's Syndrome Characteristics
- More Common in Women
- Glucocorticoids
- Decreased ACTH
- Primary Adrenal Disease
- Increased ACTH
- Pituitary Adenoma (Cushing's Disease)
- Paraneoplastic: Small Cell Carcinoma
- CRF-releasing Tumors
Azoles (Ketoconazole)
- "-azole" suffix
- Local and Less Serious Systemic Mycosis
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
Selective Beta-1 Blockers
- "-olol" Suffix
- Beta-1 Selective
- Atenolol
- Esmolol
- Metoprolol
- Partial Beta agonists
- Acebutolol
Nonselective Beta-Blockers
- "-olol" Suffix
- Nonselective
- Propranolol
- Timolol
- Nadolol
- Partial β Agonist
- Pindolol
- Nonselective β with α Blocking
- Carvedilol
- Labetalol