Pharmacotherapeutics for Advanced Nursing Practice, 1st. Ed., Demler & Rhoads, 2018 | Nurse Practitioner (NP) School Study Aid
Pox Virus
- Enveloped
- Double-Stranded DNA
- Linear
- Non-Icosahedral
- Smallpox
- Cowpox
- Molluscum Contagiosum
- Umbilicated Flesh-Colored Domed Lesions
Genital Herpes
- Herpes Simplex Virus 1 and 2 (HSV)
- May Be Asymptomatic
- Oral or Genital Lesions
- Vesicles in Clusters
- Pain
- Flu-like Symptoms
- Acyclovir
- Valacyclovir
- Famciclovir
- Infectious During Recurrences
Herpes Simplex Virus (HSV)
- Enveloped
- Double Stranded DNA
- Linear
- Type 1 HSV
- Gingivostomatitis
- Keratoconjunctivitis
- Encephalitis of Temporal Lobes
- Latent in Trigeminal Ganglia
- Type 2 HSV
- Genital Vesicles
- Neonatal Herpes
- TORCHES
- Latent in Sacral Ganglia
- Tzanck Test
- Multinucleated Giant Cells
- Cowdry A Inclusions
- Acyclovir
Varicella (Chickenpox)
- Varicella Zoster Virus (VZV)
- Red Maculopapular Rash
- Vesicles Ooze and Crust
- Pruritus
- Centripetal
- Varicella Immunization
- Skin Care to Minimize Itching
- Isolate until Vesicles Crust
Herpes Zoster (Shingles)
- Varicella-Zoster Virus
- Linear, Unilateral Rash Along a Dermatome
- Pruritus
- Postherpetic Neuralgia
- Acyclovir
- Analgesics
- Gabapentin
- Contagious Vesicles
- Shingrix
Adenovirus
- Non-enveloped
- Icosahedral
- Linear
- Double Stranded DNA
- Pharyngitis
- Conjunctivitis
- Fever
- Summer Swimming
- Day Care Centers
- Acute Hemorrhagic Cystitis
- Pneumonia
Hepatitis B (HBV) Assessment
- Bodily Fluids
- Blood Transmission
- People Who Use IV Drugs
- Variable 1-6 Months
- Fever
- Nausea and Vomiting
- Hepatomegaly
- Cirrhosis
- Hepatocellular Carcinoma
- Vaccination
Genital Warts - Condylomata Acuminata
- Human Papillomavirus (HPV)
- Papillary Cauliflower Like Growths
- Bleeding
- Vaginal Discharge
- Wart Removal
- Trichloroacetic acid (TCA)
- Podophyllin resin
- Cryotherapy
- HPV Vaccine
- Cervical Cancer
HIV CD4+ 100
- Aspergillus fumigatus
- Cryptococcus neoformans
- Candida albicans (Esophagitis)
- Mycobacterium avium complex (MAC)
- Cytomegalovirus (CMV)
- Epstein-Barr virus (EBV) B-cell lymphoma
- Toxoplasma gondii
- Cryptosporidium
- Bartonella henselae
HIV CD4+ 200
- Herpes Simplex Virus (HSV)
- JC Virus
- Progressive Multifocal Leukoencephalopathy (PML)
- Pneumocystis Pneumonia
- (HIV) Dementia
- Histoplasmosis
HIV CD4+ 500
- Candida albicans (Oral Thrush)
- Kaposi's Sarcoma (HHV-8)
- Human Papillomavirus (HPV)
- Epstein-Barr Virus (Oral Hairy Leukoplakia)
HIV Prophylaxis Medications
- CD4+ < 200
- TMP-SMX
- Pneumocystis Pneumonia
- CD4+ < 100 Susceptible to Toxoplasma Gondii
- CD4+ < 50
- Mycobacterium Avium and Intracellulare
- Azithromycin If Delayed Therapy
Protease Inhibitors
- End in "-navir"
- HIV/AIDS
- Hepatitis C
- Inhibit Protease
- Unable to Cleave Proteins
- Inhibits Maturation of New Virus
- GI Distress
- Nephropathy
- Lipodystrophy
- Hyperglycemia
Integrase Inhibitors
- -gravir Suffix
- HIV
- Blocks Insertion of Viral Genome
- Inhibit Actions of Integrase
- Hypercholesterolemia
- Increased LFT's
- Insomnia
- Increased Creatine Kinase (CK)
NRTIs (Nucleoside Reverse Transcriptase Inhibitors)
- HIV
- Pregnancy and Prophylaxis given ZDV
- Inhibit Nucleotide Binding to Reverse Transcriptase
- Chain Termination
- Require Phosphorylation
NNRTIs (Non-nucleoside Reverse Transcriptase Inhibitors)
- HIV
- Do Not Require Intracellular Metabolism
- Inhibits Reverse Transcriptase
- Rash
- Hepatotoxicity
- Vivid Dreams and CNS Symptoms
- Pregnancy
Acyclovir (Zovirax)
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Headache
- GI Distress
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Prevents Recurrent Episodes
- Slow IV Infusion
Cidofovir
- CMV Retinitis
- Acyclovir-Resistant HSV
- Inhibits Viral DNA Polymerase
- Nephrotoxicity
- Administer with Probenecid and IV Saline
Foscarnet
- CMV Retinitis
- Acyclovir-resistant HSV
- Does Not Require Activation (by Viral Kinase)
- Inhibits Viral DNA Polymerase
- Pyrophosphate Analog
- Resistance through Mutated DNA Polymerase
- Nephrotoxicity
- Electrolyte Abnormalities
- Hypokalemia
- Hypocalcemia
- Hypomagnesemia