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Pharmacotherapeutics for Advanced Nursing Practice, 1st. Ed., Demler & Rhoads, 2018/
Androgens, Estrogens, and ProgestinsLearn Androgens, Estrogens, and Progestins Mnemonics
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Pharmacotherapeutics for Advanced Nursing Practice, 1st. Ed., Demler & Rhoads, 2018 | Nurse Practitioner (NP) School Study Aid
Ovulatory Hormones I - Follicular Phase
- Characteristics
- 0-14 Days
- GnRH Stimulates FSH and LH
- Follicle Secretes Estrogen
- Negative Feedback from Estrogen
- Increased Estrogen Leads to Positive Feedback
- FSH and LH Surge
- LH Spike Leads to Ovulation
2 mins
Ovulatory Hormones II - Luteal Phase
- Days 15-28
- Corpus Luteum
- Secretes Progesterone
- Negative Feedback inhibits FSH and LH
- No pregnancy forms Corpus Albicans
- Stops Estrogen Secretion
- Endometrial Sloughing - Menses
- GnRH secretion produces new follicular phase
2 mins
Menopause Lab Findings
- Decreased Estrogen
- Lack of Negative Feedback
- Increased FSH
- Increased LH
- Increased GnRH
- Small Amount of Estrogen From Androgen Conversion
- Increased Androgens = Hirsutism
1 min
Menopause Symptoms
- Symptoms
- HAVOCS Mnemonic
- Hot Flashes
- Atrophy of Vagina
- Osteoporosis
- Coronary Artery Disease (CAD)
- Sleep disturbances
50 secs
Tamoxifen
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Antagonist on Breast Tissue
- Indications
- ER-positive Breast Cancer
- Side Effects
- Decreased Risk of Osteoporosis
- Increased Risk of Endometrial Cancer
- Increased Risk of Venous Thromboembolism (VTE)
1 min
Leuprolide
- Mechanism
- GnRH Agonist (Pulsatile Use)
- GnRH Antagonist (Continuous Use)
- Upregulates FSH And LH
- Downregulates FSH And LH
- Indications Pulsatile
- Infertility
- Indications Continuous
- Prostate Cancer
- Precocious Puberty
- Uterine Fibroids
- Endometriosis
- Side Effects
- Anti-androgenic Effects
2 mins
Clomiphene
- Indications
- Infertility
- Polycystic Ovarian Syndrome (PCOS)
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Hypothalamus
- Estrogen Antagonist
- Increased GnRH, LH and FSH Secretion
- Induction of Ovulation
- Side Effects
- Multiple Gestations
- Visual Disturbances
- Hot Flashes
2 mins
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