Registered Nurse (RN)
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NCLEX®/
NCLEX-RN® Test Plan: Client Needs/
Adverse Effects/Contraindications/Side Effects/InteractionsAce Your NCLEX-RN® Test Plan: Client Needs Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Registered Nurse (RN) Students
With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing. Whether you're studying for your classes or getting ready for a big exam, we're here to help.
NCLEX-RN® Test Plan: Client Needs | Registered Nurse (RN) School Study Aid
Adverse Effects/Contraindications/Side Effects/Interactions
290 Picmonics to Learn | 8 hrs 30 mins
Benzodiazepine Antidote
- Antidote
- Flumazenil
40 secs
Warfarin Antidotes
- Antidotes
- Vitamin K
- Fresh Frozen Plasma
59 secs
Acetylcholinesterase Inhibitor Antidote
- Antidote
- Atropine
- Pralidoxime
1 min
Acetaminophen Antidote
- Antidote
- N-Acetylcysteine
33 secs
Antimuscarinic Antidote
- Antidote
- Physostigmine Salicylate
44 secs
Amphetamine Antidote
- Antidote
- Ammonium Chloride (NH4Cl)
- Acidify Urine
34 secs
Beta Blocker Antidote
- Antidote
- Glucagon
29 secs
Arsenic, Gold and Copper Antidotes
- Toxic Metals
- Arsenic
- Gold
- Copper
- Antidotes
- Penicillamine
- Dimercaprol (BAL)
- Succimer
2 mins
Iron Antidote
- Antidote
- DeFEroxamine
23 secs
Opioid Antidote
- Antidote
- Naloxone
29 secs
Tricyclic Antidepressant (TCA) Antidote
- Antidote
- Sodium Bicarbonate (NaHCO3)
27 secs
Aspirin Poisoning (Salicylism) Assessment
- Early Symptoms
- Nausea and Vomiting
- Tinnitus
- Confusion
- Hyperventilation
- Respiratory Alkalosis
- Late Symptoms
- Metabolic Acidosis
- Coma
- Hyperthermia
1 min
Lead Antidotes
- Antidotes
- Dimercaprol
- CaEDTA
- Succimer
39 secs
Anticholinergics
- B.O.AT.S Acronym
- Benztropine
- Parkinson's Disease
- Oxybutynin
- Decrease bladder spasms
- Atropine
- Mydriasis and Cycloplegia
- Scopolamine
- Motion Sickness
1 min
Anticholinergics Continued
- Drugs
- Glycopyrrolate
- Reduces Airway Secretions
- Ulcer Treatment
- Ipratropium
- Asthma and C.O.P.D
- Dicyclomine
- Hyoscyamine
- Irritable Bowel Syndrome
1 min
Atropine
- Mechanism of Action
- Muscarinic Antagonist
- Indications
- Bradycardia
- Increased Exocrine Secretions
- Smooth Muscle Spasms
- Side Effects
- Tachycardia
- Dry Mouth
- Urinary Retention
2 mins
Benztropine (Cogentin)
- Mechanism
- Anticholinergic
- Indications
- Parkinson's Disease
- Acute Dystonia
- Side Effects
- Mydriasis
- Dry Mouth
- Urinary Retention
- Tachycardia
- Constipation
- Psychosis
1 min
Direct Cholinomimetics
- Muscarinic Agonists
- Bethanechol
- Bladder and Bowels
- Methacholine
- Bronchoconstriction
- Pilocarpine
- Contracts Ciliary Muscle and Pupillary Sphincter
- Carbachol
- Releases Intraocular Pressure
1 min
Indirect Cholinomimetics
- Acetylcholinesterase Inhibitors
- Doesn't Cross BBB
- Edrophonium
- Myasthenia Gravis (Diagnosis)
- Pyridostigmine and Neostigmine
- Myasthenia Gravis (Tx)
- Ileus
- Crosses BBB
- Physostigmine
- Atropine Overdose
- Glaucoma
- Donepezil
- Alzheimer's
2 mins
Pilocarpine (Pilocar)
- Mechanism
- Direct Cholinergic Agonist
- Contracts Iris Sphincter
- Contracts Ciliary Muscle
- Indications
- Xerostomia
- Glaucoma
- Side Effects
- Detached Retina
- Decreased Visual Acuity
- Eye Irritation
- Cholinergic Effects
- Considerations
- Avoid with Asthma or Bradycardia
2 mins
Acetylcholinesterase Inhibitor Poisoning
- DUMBBELSS
- Diarrhea
- Urination
- Miosis
- Bronchospasm
- Bradycardia
- Emesis
- Lacrimation
- Salivation
- Sweating
2 mins
Alpha Agonists
- -RINE suffix
- Norepinephrine
- Hypotension
- Phenylephrine
- Hypotension
- Congestion
- Ephedrine
- Congestion
- Urinary Incontinence
- Hypotension
- Epinephrine
- Anaphylaxis and Asthma
- Hypotension
1 min
Prazosin (Minipress)
- -osin suffix
- Mechanisms
- Selective Alpha-1 Receptor Blocker
- Indications
- Hypertension
- Benign Prostatic Hyperplasia (BPH)
- Nightmares
- Side Effects
- Orthostatic Hypotension
- Tachycardia
- Priapism / Inhibition of Ejaculation
- Nasal Congestion
- Considerations
- First Dose Effect
- Administer at Bedtime
2 mins
Beta Blockers
- "-olol" suffix
- Mechanism
- Decreases Heart Rate and Contractility
- Decreases Peripheral Vascular Resistance
- Decreases Renin Release
- Indications
- Hypertension
- Heart Failure
- Angina Pectoris
- Contraindications
- Asthma and Heart Block Patients
- Nursing Considerations
- Assess Blood Pressure and Heart Rate
- Masking Signs of Hypoglycemia
- Do Not Stop Abruptly
2 mins
Cardiovascular Effects of Beta-Blockers
- Cardiac Myocytes and Vasculature
- Decrease cAMP
- Decreases SA and AV Node Conduction Velocity
- Lower Blood Pressure
- Decrease O2 Consumption
- Decreases Mortality Post-MI
2 mins
Systemic Effects of Beta-Blockers
- Respiratory
- Bronchoconstriction
- Metabolic
- Decreased Insulin
- Decreased Glycolysis and Lipolysis
- Eye
- Reduces Intraocular Pressure
1 min
Epinephrine (Adrenaline)
- Mechanism
- Alpha and Beta Agonist
- Indications
- Anaphylaxis
- Primary Open Angle Glaucoma (POAG)
- Bleeding
- Cardiac Arrest
- Side Effects
- Tachycardia
- Hypertension
- Tremors
- Insomnia
- Considerations
- Multiple Strengths
2 mins
Ephedrine
- Mechanism of Action
- Alpha Agonist
- Beta Agonist
- Indications
- Rhinitis
- Hypotension
- Urinary Incontinence
35 secs
Norepinephrine (Levophed)
- Mechanism of Action
- Alpha Agonist
- Beta-1 Agonist
- Indications
- Severe Hypotension
- Side Effect
- Decreases Renal Blood Flow
- Arrhythmias
- Hypertension
- Considerations
- Tissue Necrosis
- Last Resort Medication
2 mins
Dobutamine
- Mechanism
- Beta-1 Agonist
- Inotropic
- Indications
- Heart Failure
- Side Effects
- Tachycardia
- Arrhythmias
- Considerations
- Closely Monitor Patients
- Other Meds May Increase Potency
1 min
Selective Serotonin Reuptake Inhibitor (SSRI) Overview
- Indications
- Depression
- Anxiety
- Mechanism of Action
- Selective Serotonin Reuptake Inhibitors
- Drugs
- Paroxetine
- Sertraline
- Escitalopram
- Fluoxetine
- Side Effects
- Sexual Dysfunction
- Serotonin Syndrome
- Treat with Cyproheptadine
2 mins
Fluoxetine (Prozac)
- Mechanism of Action
- Inhibits Reuptake of Serotonin
- Indications
- Depression
- Side Effects
- Sexual Dysfunction
- CNS Stimulation
- Weight Changes
- Serotonin Syndrome
- Contraindications
- No MAO-Is
- No Anticoagulants / Antiplatelets
- Considerations
- Suicide Risk
- Delayed Onset of Action
2 mins
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
- Indications
- Depression
- Diabetic Peripheral Neuropathy
- Duloxetine
- Panic and Anxiety
- Venlafaxine
- Mechanism of Action
- Inhibits Reuptake of Serotonin and NE
- Side Effects
- Hypertension
- Insomnia
- Nausea and Vomiting
- Decreased Libido
1 min
Bupropion
- Indications
- Depression
- Smoking Cessation
- Mechanism of Action
- Increase Dopamine and NE
- Side Effects
- Stimulant Side Effects
- Seizure
1 min
Tricyclic Antidepressants (TCAs)
- Mechanism of Action
- Inhibits Reuptake of Norepinephrine and Serotonin
- Indications
- Depression
- Bipolar Disorder
- Fibromyalgia
- Side Effects
- Sedation
- Orthostatic Hypotension
- Anticholinergic Effects
- Cardiac Toxicity
- Considerations
- Delayed Effect
- Do Not Stop Abruptly
2 mins
Tricyclic Antidepressants (TCAs) Indications
- Indications
- Major Depression
- Bedwetting
- Fibromyalgia
- OCD
- Drugs
- -Iptyline or -Ipramine Suffix
- Amitriptyline
- Desipramine
- Clomipramine
- Imipramine
- Nortriptyline
2 mins
Monoamine Oxidase Inhibitor (MAOI) Contraindications
- Contraindications
- Wine and Cheese
- Hypertensive Crisis
- Serotonin Drugs
- Serotonin Syndrome
1 min
Monoamine Oxidase Inhibitors (MAO-Is)
- Indications
- Atypical Depression
- Mechanism of Action
- Increase Levels of Amine Neurotransmitters
- Drugs
- "Takes Pride In Shanghai"
- Tranylcypromine
- Phenelzine
- Isocarboxazid
- Selegiline
1 min
Aripiprazole (Abilify)
- Mechanism
- 2nd Generation Atypical Antipsychotic
- Indications
- Schizophrenia
- Bipolar Disorder
- Depression
- Side Effects
- Headache
- Dizziness
- Nausea and Vomiting
- Insomnia
- Anxiety
- Considerations
- Low Risk of Extrapyramidal Symptoms
- Lowest Risk of Weight Gain
2 mins
Serotonin Syndrome Assessment
- Mild Signs & Symptoms
- Restlessness
- Diaphoresis
- Tachycardia
- Hypertension
- Diarrhea
- Moderate Signs & Symptoms
- Hyperthermia
- Decreased Level of Consciousness
- Muscle Rigidity
- Severe Signs & Symptoms
- Seizure and Coma
- Treatment
- Cyproheptadine
2 mins
Vortioxetine
- Mechanism of Action
- Inhibits Reuptake of Serotonin
- Indication
- Major Depressive Disorder
- Side Effects
- Nausea
- Sexual Dysfunction
- Anticholinergic Effects
- Sleep Disturbances
- Considerations
- Serotonin Syndrome
2 mins
Antipsychotics Overview
- Generations
- Typical
- Atypical
- Mechanism
- Blocks D2 Receptor
- 2nd Generation Blocks the 5-HT 2 Receptor
- Indications
- Psychosis
- Delirium
- Bipolar Disorder
- Tourette’s Syndrome
- Side Effects
- Hyperprolactinemia
- Extrapyramidal Symptoms
- Tardive Dyskinesia
- Neuroleptic Malignant Syndrome
4 mins
Low Potency Antipsychotic Drugs
- Drugs
- Chlorpromazine
- Corneal Deposits
- Thioridazine
- Retinal Deposits
- Shared Side Effects
- Alpha1 Antagonist Effects
- Anticholinergic Effects
- Antihistamine Effects
2 mins
High Potency Antipsychotic Drugs
- High Potency Drugs
- Fluphenazine
- Trifluoperazine
- Haloperidol
- Pimozide
- Side Effects
- Extrapyramidal Symptoms
- Short Term
- Dystonia
- Restlessness (Akathisia)
- Torticollis
- Long Term
- Tardive Dyskinesia
- Parkinson's-Like Symptoms
- Neuroleptic Malignant Syndrome
3 mins
Atypical Antipsychotics
- Indications
- Schizophrenia
- Mechanism of Action
- Unknown Mechanism
- Side Effects
- Seizures
- Prolonged QT Interval
- Agranulocytosis
- Weight Gain
- Fewer Extrapyramidal Side Effects
- Fewer Anticholinergic Side Effects
2 mins
Neuroleptic Malignant Syndrome
- FEVER Acronym
- Fever
- Encephalopathy
- Vital Signs Unstable
- Elevated Enzymes
- Rigidity of muscles
- Reversal Agent
- D2 Agonists
- Bromocriptine
- Dantrolene
2 mins
Malignant Hyperthermia vs. Neuroleptic Malignant Syndrome vs. Serotonin Syndrome
- Autonomic Instability
- Muscle Rigidity
- Malignant Hyperthermia
- Ryanodine Receptor 1 Mutation
- Inhaled Anesthetics
- Succinylcholine
- Dantrolene
- Neuroleptic Malignant Syndrome
- Antidopaminergic Medications
- Hyporeflexia
- Myoglobinuria
- Dantrolene
- Serotonin Syndrome
- Serotonergic Medications
- Hyperreflexia
- Clonus
- Cyproheptadine
3 mins
Haloperidol (Haldol)
- Mechanism
- High Potency Antipsychotic
- Indications
- Migraine
- Schizophrenia
- Side Effects
- Extrapyramidal Symptoms
- Weight Gain
- QT Prolongation
- Restlessness
- Considerations
- Caution in Seizure Patients
- Neuroleptic Malignant Syndrome
2 mins
Chlorpromazine (Thorazine)
- Mechanism
- Low Potency Antipsychotic
- Indications
- Schizophrenia
- Hiccups
- Side Effects
- Sedation
- Weight Gain
- Orthostatic Hypotension
- Anticholinergic Effects
- QT Prolongation
- Neuroendocrine Effects
- Caution in Seizure Patients
- Corneal Deposits
2 mins
Clozapine (Clozaril)
- Mechanism
- Atypical Antipsychotic
- Indications
- Schizophrenia
- Levodopa-Induced Psychosis
- Side Effects
- Weight Gain
- Hypersalivation (Sialorrhea)
- Myocarditis
- Agranulocytosis
- Sedation
- Orthostatic Hypotension
- Constipation (Risk of Bowel Ileus)
- Considerations
- Weekly Lab Tests
2 mins
Risperidone (Risperdal)
- Mechanism
- Atypical Antipsychotic
- Indications
- Schizophrenia
- Bipolar Mania
- Autism-Associated Irritability
- Side Effects
- Extrapyramidal Symptoms
- Hyperprolactinemia
- Gynecomastia
- Galactorrhea
- Amenorrhea
- Prolonged QT
- Considerations
- Intramuscular Long Acting (Depot) Form
2 mins
Lithium
- Mechanism of Action
- Mood Stabilizer
- Unknown Mechanism
- Indications
- Bipolar Disorder
- Side Effects
- Nephrogenic Diabetes Insipidus
- Hypothyroidism
- Tremor
- Heart Block
- Contraindication
- Pregnancy
- Considerations
- Monitor Plasma Levels
2 mins
Triazolam (Halcion)
- Mechanism
- Rapid-Onset Benzodiazepine
- Indications
- Insomnia
- Side Effects
- Rebound Insomnia
- Respiratory Depression
- Hypotension
- Paradoxical Excitement
- Amnesia
- Confusion
- Contraindications
- Pregnancy
- Considerations
- Short-Term Administration
2 mins
Zolpidem (Ambien)
- Mechanism
- Hypnotic
- Indications
- Insomnia
- Side Effects
- Daytime Drowsiness
- Bizarre Sleep Behaviors
- Sleep Driving
- Angioedema
- Considerations
- Short Term Administration
- Take Immediately Before Bedtime
1 min
Diazepam (Valium)
- Indications
- Anxiety
- Seizures and Status Epilepticus
- Muscle Spasms
- Alcohol Withdrawal
- Side Effect/Assessment
- Dizziness/Vision Changes
- Confusion/Amnesia
- Urinary Incontinence
- Behavioral Changes
- Respiratory Depression
- Antidote
- Flumazenil (Romazicon)
- Nursing Considerations
- Fall Precaution
- Do Not Stop Abruptly
2 mins
Phenobarbital (Barbiturates)
- Mechanism
- Barbiturate
- Indications
- Seizures
- Side Effects
- Ataxia
- Paradoxical Excitement
- Fatigue/Drowsiness
- Considerations
- Monitor Plasma Levels
- High Potential for Abuse
1 min
Buspirone (Buspar)
- Mechanism
- Increases Serotonin
- Indications
- Anxiety
- Side Effects
- Dizziness
- Insomnia
- Considerations
- Delayed Effect
- Safer with Alcohol than Other Anxiolytics
- Low Side Effect Profile
- Low Abuse Potential
1 min
Trazodone
- Indications
- Insomnia
- Depression
- Mechanism of Action
- Inhibit Serotonin Reuptake
- Alpha-1 Blocker
- Histamine (H1) Blocker
- Side Effects
- Sedation
- Orthostatic Hypotension
- Dry Mouth
- Priapism
- Arrhythmias
2 mins
Short-acting Benzodiazepines
- Mnemonic
- ATOM
- Drug Names
- Alprazolam
- Triazolam
- Oxazepam
- Midazolam
- Indications
- Anesthesia Induction
- Insomnia
- Anxiety
- Considerations
- Half-life < 12 Hours
- Dependence
2 mins
Benzodiazepines Overview
- Indications
- First Line for Status Epilepticus
- Anesthesia Induction
- Anxiety
- Eclampsia
- Detoxification
- Mechanism of Action
- '-zepam' and '-zolam" Suffix
- Increase Frequency of Cl- Channel Opening
- Side Effects
- Decrease REM Sleep
- CNS Depression
- Dependence
- Antidote
- Flumazenil for Overdose
2 mins
Long-acting Benzodiazepines
- Drug Names
- Lorazepam
- Diazepam
- Clonazepam
- Chlordiazepoxide
- Indications
- Insomnia
- Anxiety
- Seizures
- Eclampsia
- Alcohol Withdrawal
- Considerations
- Half-life > 24 Hours
- Dependence
3 mins
CNS Stimulants
- Indications
- Attention Deficit Hyperactivity Disorder (ADHD)
- Obesity
- Mechanism of Action
- Increase Catecholamines at Synaptic Cleft
- Increase Norepinephrine
- Increase Dopamine
- Drug Names
- Methylphenidate (Ritalin)
- Methamphetamine
- Side Effect
- Potential for Abuse
57 secs
CNS Stimulant Indications
- Drug Names
- Amphetamine
- Methylphenidate (Ritalin)
- Mechanism of Action
- Increased Norepinephrine
- Increased Dopamine
- Indications
- Attention Deficit Hyperactivity Disorder (ADHD)
- Obesity
- Narcolepsy
1 min
CNS Stimulant Side Effects
- Side Effects
- Agitation
- Insomnia
- Hypertension
- Tachycardia
- Tics
- Anorexia
- Considerations
- Tolerance Develops
- High Risk of Abuse and Dependence
2 mins
Amphetamines Intoxication Assessment
- Euphoria
- Insomnia
- Mydriasis
- Diaphoresis
- Hypertension
- Tachycardia
- Paranoia
- Anxiety
- Anorexia
- Seizures
2 mins
Cocaine Intoxication Assessment
- Euphoria
- Delusions
- Mydriasis
- Hallucinations
- Agitation
- Hypertension
- Arrhythmias
- Hyperthermia
- Seizures
- Nasal Septum Perforation
2 mins
Local Anesthetic Overview
- Indications
- Minor Procedures
- Epidurals
- Mechanism of Action
- Blocks Na+ Channels
- State Dependent
- Combined with Vasoconstrictors
- Infected Tissue Requires Higher Dose
- Drugs
- Esters
- Amides
- Side Effects
- Arrhythmias
- Cardiotoxicity
1 min
Inhaled Anesthetics
- Mechanism of Action
- Unknown Mechanism
- Inhaled Anesthetic Drugs
- HEISMN Drug Name Acronym
- Side Effects
- Respiratory Depression
- Myocardial Depression
- Lower Metabolic Demand, Increased Cerebral Blood Flow
- Hepatotoxicity (Halothane)
- Nephrotoxicity (Methoxyflurane)
- Seizure (Enflurane)
- Malignant Hyperthermia
- Expansion of Trapped Gas
2 mins
IV Anesthetics
- Barbiturates
- Benzodiazepines
- Respiratory Depression
- Hypotension
- Ketamine
- NMDA Receptor Antagonist
- Hallucinations
- Opioids
- Propofol
- Potentiates GABA-A
2 mins
Lidocaine
- Mechanism
- Blocks Na+ Channels
- Indications
- Ventricular Arrhythmia
- Anesthetic
- Side Effects
- Paresthesias
- Seizures
- Respiratory Depression
- Drowsiness
- Consideration
- Anesthetic Effects Extended with Epinephrine
1 min
Malignant Hyperthermia
- Inheritance
- Autosomal-Dominant
- Pathophysiology and causes
- Ryanodine Receptor 1 Mutation
- Inhaled Anesthetics
- Succinylcholine
- Symptoms
- Autonomic Instability
- Muscle Rigidity
- Treatment
- Dantrolene
2 mins
Lamotrigine (Lamictal)
- Mechanism
- Blocks Na+ Channels
- Indications
- Seizures
- Bipolar Disorder
- Side Effects
- Diplopia
- Stevens-Johnson Syndrome
- Headache
- Aseptic Meningitis
- Nausea and Vomiting
- Considerations
- Screen for Suicide Risk
2 mins
Phenytoin (Dilantin)
- Mechanism
- Blocks Na+ Channels
- Indications
- Tonic-clonic Seizures
- Side Effects
- Ataxia
- Nystagmus
- Sedation
- Gingival Hyperplasia
- Purple Glove Syndrome
- Hirsutism
- Rash
- Anemia
- Considerations
- Individualized Dosing
2 mins
Valproic Acid (Depakote)
- Mechanism
- Blocks Na+ Channels
- Increases GABA Concentration
- Indications
- Tonic-clonic Seizures
- Bipolar Disorder
- Migraine Prophylaxis
- Side Effects
- Hepatotoxicity
- Blood Dyscrasias
- GI Distress
- Tremor
- Pancreatitis
1 min
Carbamazepine (Tegretol)
- Mechanism
- Inactivates Na+ Channels
- Indications
- Seizures
- Bipolar Disorder
- Trigeminal Neuralgia
- Side Effects
- Nystagmus
- Ataxia
- Hepatotoxicity
- Blood Dyscrasias
- Water Retention
- Stevens-Johnson Syndrome
- Considerations
- Avoid Grapefruit Juice
2 mins
Ethosuximide (Zarontin)
- Indications
- First Line Absence Seizure
- Mechanism of Action
- Blocks Thalamic T-Type Ca2+ Channels
- Side Effects
- Stevens-Johnson Syndrome
- Fatigue
- Diarrhea
- Blood Dyscrasias
- Considerations
- Do Not Stop Abruptly
2 mins
Topiramate
- Indications
- Seizure Treatment
- Migraine Prophylaxis
- Mechanism of Action
- Increase GABA Action
- Blocks Voltage-Gated Na+ Channels
- Side Effects
- Kidney Stones
- Weight Loss
- Sedation
1 min
Valproic Acid (Valproate) Side Effects
- V-A-L-P-R-O-A-T-E
- Vomiting
- Alopecia
- Liver Toxicity
- Pancreatitis/Pancytopenia
- Retain Fat (Weight Gain)
- Oedema (Edema)
- Appetite Increase
- Tremor
- Enzyme Inhibitor (P450)
2 mins
Pregabalin (Lyrica)
- Mechanism
- GABA Analog
- Indications
- Seizures
- Neuropathic Pain
- Fibromyalgia
- Side Effects
- Headache
- Dizziness
- Somnolence (Fatigue)
- Weight Gain
- Angioedema
- Rhabdomyolysis
- Considerations
- Dependence
1 min
Nondepolarizing Neuromuscular Blocking Drugs
- Names Include "Cur"
- Competitive Antagonists
- Acetylcholine Competition
- Reversal of Blockade
- Neostigmine, Edrophonium
1 min
Succinylcholine
- Indications
- Inducing Paralysis
- Mechanism of Action
- Neuromuscular Blocking Drugs
- Motor Nicotinic Receptor
- ACh Receptor Agonist
- Depolarization
- Phases of Action
- Phase I (Paralysis Non-reversible)
- Phase II (Paralysis Reversible)
- Neostigmine (Reversal Agent)
2 mins
Parkinson's Drugs
- Parkinsons Characteristics
- Decreased Dopamine
- Increased Acetylcholine
- Drug Names
- BALSA Acronym
- Bromocriptine
- Amantadine
- Levodopa
- Selegiline
- Antimuscarinics
2 mins
Levodopa/Carbidopa (Sinemet)
- Mechanism
- Increases Dopamine in Brain
- Indications
- Parkinson's Disease
- Side Effects
- Nausea and Vomiting
- Arrhythmias
- Dyskinesia
- Psychosis
- Orthostatic Hypotension
- Considerations
- Report Uncontrolled Movements
- Darkened Sweat or Urine
- Off and On Phenomenon
2 mins
Memantine
- Indications
- Alzheimer's Disease
- Mechanism of Action
- NMDA Receptor Antagonist
- Prevents Excitotoxicity
- Side Effects
- Confusion
- Hallucinations
1 min
Donepezil
- Indications
- Alzheimer's Disease
- Mechanism of Action
- Acetylcholinesterase Inhibitor
- Increased Acetylcholine
- Side Effects
- Nausea and Vomiting
- Dizziness
52 secs
Sumatriptan
- Mechanism of Action
- Short Half-Life
- 5-HT Agonist
- Inhibits Trigeminal Nerve Activation
- Induces Vasoconstriction
- Indications
- Migraine
- Cluster Headache
- Side Effects
- Increased Risk of Serotonin Syndrome
- Paresthesias
- Coronary Vasospasm
- Contraindication
- Prinzmetal's Angina
- Coronary Artery Disease (CAD)
3 mins
Gabapentin
- Primary Indication
- Seizure Treatment
- Secondary Indications
- Peripheral Neuropathy
- Postherpetic Neuralgia
- Bipolar Disorder
- Migraine Prophylaxis
- Characteristics
- Inhibits Voltage-Gated Ca2+ channels
- Designed as a GABA Analog
- Side Effects
- Ataxia
- Sedation
2 mins
Codeine
- Mechanism
- Opioid Receptor Agonist
- Indications
- Mild to Moderate Pain
- Cough Suppressant
- Side Effects
- Sedation
- Constipation
- Miosis
- Considerations
- Close Monitoring When Breast Feeding
- Often Combined with Non-Opioids
2 mins
Morphine
- Mechanism
- Opioid Receptor Agonist
- Indications
- Pain
- Myocardial Infarction
- Side Effects
- Nausea and Vomiting
- CNS Depression
- Biliary Colic
- Constipation
- Increased Intracranial Pressure (ICP)
- Pupillary Constriction
- Hypotension
2 mins
Meperidine (Demerol)
- Mechanism
- Opioid Receptor Agonist
- Indications
- Moderate to Severe Pain
- Post Anesthesia Shivering
- Side Effects
- Tremors
- Constipation
- CNS Depression
- Sedation
- Considerations
- Short Term Administration
- Increased Risk Serotonin Syndrome
- Does NOT cause Miosis
- Renal Failure Increases Toxicity Risk
2 mins
Naloxone (Narcan)
- Mechanism
- Competitive Opioid Receptor Antagonist
- Indications
- Opioid Induced CNS Depression
- Side Effects
- Severe Nausea and Vomiting
- Excitable State
- Opioid Withdrawal Symptoms
- Considerations
- Repeated Dosing Often Required
1 min
Tramadol
- Indications
- Chronic Pain
- Mechanism of Action
- Weak Opioid
- Inhibit Serotonin and NE reuptake
- Side Effect
- Increased Risk of Seizure
48 secs
Butorphanol
- Indications
- Migraine
- Severe Pain
- Labor
- Mechanism of Action
- Partial Agonist at Mu and Full Agonist at Kappa Receptors
- Less Respiratory Depression
- Side Effects
- Withdrawal Symptoms
1 min
Acetaminophen-Hydrocodone (Vicodin)
- Mechanism of Action
- Combination Analgesic
- Opioid Receptor Agonist
- Hydrocodone
- Reversible Inhibition of COX
- Acetaminophen
- Indication
- Moderate to Severe Pain
- Side Effects
- CNS Depression
- Respiratory Depression
- Hepatotoxicity
- Considerations
- Addiction
2 mins
Oxycodone
- Mechanism of Action
- Opioid Receptor Agonist
- Indication
- Refractory Pain
- Side Effects
- Respiratory Depression
- Constipation
- CNS Depression
- Considerations
- Addiction
- Naloxone
2 mins
Suvorexant
- Mechanism of Action
- Orexin Receptor Antagonist
- Indications
- Insomnia
- Side Effects
- CNS Depression
- Headache
- Abnormal Dreams
- Considerations
- Contraindicated in Narcolepsy
- Avoid in Liver Disease
1 min
Fentanyl
- Mechanism of Action
- Opioid Receptor Agonist
- High Potency
- Indications
- Anesthesia Induction
- Chronic Pain
- Breakthrough Pain
- Side Effects
- CNS Depression
- Respiratory Depression
- Constipation
- Miosis
- Considerations
- Addiction
3 mins
Buprenorphine-Naloxone (Suboxone)
- Mechanism of Action
- Combination Drug
- Partial Opioid Receptor Agonist (Buprenorphine)
- Opioid Receptor Antagonist (Naloxone)
- Indication
- Opioid Use Disorder
- Side Effects
- CNS Depression
- Diaphoresis
- Hypotension
- Considerations
- Low Abuse Potential
2 mins
Acetazolamide
- Indications
- Glaucoma
- Altitude Sickness
- Pseudotumor Cerebri
- CHF
- Metabolic Alkalosis
- Mechanism of Action
- Carbonic Anhydrase Inhibitor
- Sodium Bicarbonate (NaHCO3) Diuresis
- Side Effects
- Metabolic Acidosis
- Paresthesias
1 min
Hypertension Medications
- Diuretics
- ACE Inhibitors
- Angiotensin Receptor Blockers (ARBs)
- Beta Blockers
- Dihydropyridine Calcium Channel Blockers
2 mins
Angiotensin-Converting Enzyme (ACE) Inhibitors
- "-pril" Suffix
- Mechanism of Action
- Block Renin Angiotensin-Aldosterone System (RAAS)
- Indications
- Hypertension
- Heart Failure
- Side Effects
- Dry Non-productive Cough
- Hypotension
- Dizziness
- Possible Hyperkalemia
- Angioedema
- Nursing Considerations
- Slowly Change Position
- Do Not Stop Abruptly
2 mins
Angiotensin II Receptor Blockers (ARBs)
- Ends in "-sartan"
- Mechanism of Action
- Blocks Angiotensin II Receptor
- Indications
- Hypertension
- Side Effects
- Angioedema
- Contraindications
- Renal Artery Stenosis
- Pregnancy
1 min
Hydralazine (Apresoline)
- Indications
- Severe Hypertension
- CHF
- Reduced Afterload
- Pregnancy
- Mechanism of Action
- Vasodilates Arterioles
- Side Effects
- Drug-induced Lupus
- Reflex Tachycardia
- Hypotension
- Considerations
- Combined with Diuretic and Beta Blocker
1 min
Minoxidil (Loniten, Rogaine)
- Mechanism
- Vasodilates Arterioles
- Indications
- Severe Hypertension
- Baldness
- Side Effects
- Reflex Tachycardia
- Blood Volume Expansion
- Hypertrichosis
- Pericardial Effusion
- Rash
- Considerations
- Give with Beta Blocker and Diuretic
2 mins
Nitroglycerin
- Mechanism of Action
- Decreases Preload
- Indications
- Angina
- Up to 3 doses q 5 mins
- Side Effects
- Headache
- Hypotension
- Contraindications
- Viagra (Sildenafil)
- Nursing Considerations
- Assess Blood Pressure
- Protect From Light
- Use Glass Bottle and Special Tubing
- Gloves for Applying Topically
2 mins
Sodium Nitroprusside (Nitropress)
- Mechanism
- Venous and Arterial Dilation
- Indications
- Hypertensive Crisis
- Side Effects
- Cyanide Toxicity
- Thiocyanate Toxicity
- Hypotension
- Considerations
- Short Term Administration
- Light Sensitive, Use Container
- Continuous BP Monitoring
2 mins
K+ Sparing Diuretics
- Indications
- CHF and Hypertension
- Hypokalemia
- Hyperaldosteronism
- Mechanism of Action
- Collecting Tubule
- Spironolactone
- Competitive Aldosterone Receptor Antagonist
- Amiloride and Triamterene
- Block Na+ Channels
- Side Effects
- Hyperkalemia
- Gynecomastia
2 mins
Clonidine
- Mechanism of Action
- Alpha-2 Agonist
- Indication
- Hypertensive Urgency
- Attention Deficit Hyperactivity Disorder (ADHD)
- Tourette Syndrome
- Opioid Withdrawal
- Side Effects
- CNS Depression
- Respiratory Depression
- Hypotension
- Considerations
- Rebound Hypertension if Abrupt Cessation
2 mins
Adenosine (Adenocard)
- Mechanism
- Slows AV Conduction
- Indications
- Supraventricular Tachycardia (Paroxysmal)
- Side Effects
- Bradycardia
- Flushing
- Dyspnea
- Considerations
- Rapid IV Push
- Caffeine and Theophylline Decrease Effectiveness
- Dipyridamole May Intensify Effects
2 mins
Magnesium Sulfate
- Mechanism
- Muscle Relaxant
- Indications
- Preterm Labor Contractions
- Preeclampsia
- Side Effects
- Warm Feeling
- Hypotension
- Decreased Deep Tendon Reflexes (DTRS)
- Decreased Respiratory Rate
- Decreased Urine Output
- Paralytic Ileus
- Antidote
- Calcium Gluconate
2 mins
Calcium Channel Blockers (Verapamil and Diltiazem)
- Mechanism of Action
- Slows AV Conduction
- Indications
- Angina Pectoris
- Arrhythmias
- Essential Hypertension
- Side Effects
- Bradycardia
- Hypotension
- Constipation
- Peripheral Edema
- Gingival Hyperplasia
- Nursing Consideration
- Medication Education
2 mins
Amiodarone
- Mechanisms
- Class III Antiarrhythmic (K+ Channel Blocker)
- Decreases SA and AV Node Conduction
- Inhibits Cytochrome P450
- Indications
- Supraventricular Tachycardia with Heart Failure
- Ventricular Tachycardia
- Side Effects
- Hepatotoxicity
- Pulmonary Fibrosis
- Bradycardia
- Heart Block
- Thyroid Disorders
- Blue/Gray Skin Deposits
- Corneal Deposits
3 mins
Digoxin (Lanoxin)
- Mechanism of Action
- Increases Inotropy
- Indications
- Heart Failure
- Atrial Fibrillation
- Side Effects
- Bradycardia
- Fatigue
- Contraindications
- Heart Block
- Nursing Considerations
- Heart Rate Below 60
- Hypokalemia
- Monitor for Toxicity and Visual Changes
- Digibind
2 mins
Acute Digoxin Toxicity
- Clinical Symptoms
- Hyperkalemia
- Cholinergic (Nausea, Vomiting, Diarrhea)
- Blurry Yellow Green Vision with Halo of Light
- Arrhythmia
- Bradycardia
- EKG Changes
- Prolonged PR interval
- Decreased QT
- Scooping on EKG
- T Wave Inversion
2 mins
Digoxin Toxicity Treatment
- Activated Charcoal
- Slowly Normalize K+
- Digibind (Anti-Digoxin Fab)
- Magnesium Sulfate
- Lidocaine
- Cardiac Pacing
2 mins
Beta-1 Agonists
- Dobutamine
- Heart Failure
- Cardiac Stress Test
- Isoproterenol
- Bradyarrhythmias
- Torsades de Pointes
58 secs
Milrinone and Amrinone
- Mechanism of Action
- Phosphodiesterase 3 Inhibitor
- Potentiates Beta Receptor Effects
- Inotrope
- Vasodilator
- Indication
- Acute Decompensated Heart Failure
- Side Effects
- Ventricular Arrhythmias
- Hypotension
2 mins
Atorvastatin (Lipitor)
- Characteristics
- -statin Suffix
- Mechanism
- HMG-CoA Reductase Inhibitors
- Indications
- High Cholesterol
- Side Effects
- Hepatotoxicity
- Rash
- Rhabdomyolysis
- Myopathy
- Considerations
- Monitor Liver Enzymes
- Administer at Bedtime
- Avoid Grapefruit
2 mins
Bile Acid Resins
- Indications
- Hyperlipidemia
- Mechanism of Action
- Bile Acid Reabsorption Prevented
- Slight Increase HDL/Triglycerides
- Decrease LDL
- Drugs
- Colestipol (Colestid)
- Cholestyramine
- Colesevelam
- Side Effects
- Cholesterol Gallstones
- Decreased Absorption of Fat-soluble Vitamins
- Patients Hate It
2 mins
Bile Acid Resins
- Indications
- Hyperlipidemia
- Mechanism of Action
- Bile Acid Reabsorption Prevented
- Decrease LDL
- Drugs
- Colestipol (Colestid)
- Cholestyramine (Questran)
- Colesevelam (Welchol)
- Side Effects
- GI Distress
- Cholesterol Gallstones
- Decreased Absorption of Fat-soluble Vitamins
2 mins
Gemfibrozil (Fibrates)
- Mechanism of Action
- Decreases Triglycerides
- Increase in HDL
- Slight Decrease in LDL
- Indications
- Hypertriglyceridemia
- Side Effect
- Hepatotoxicity
- Cholesterol Gallstones
- Myopathy
- Considerations
- Do Not Combine with Statins
- Warfarin Toxicity
2 mins
Ezetimibe
- Indications
- Hyperlipidemia
- Mechanism of Action
- Cholesterol Absorption Blocker
- Decreases LDL
- Side Effects
- Diarrhea
- Increased LFT Values
1 min
Fibrates
- Indications
- Hyperlipidemia
- Mechanism of Action
- Upregulate LPL
- Decreases Triglycerides
- Slight Increase in HDL
- Slight Decrease in LDL
- Side Effect
- Hepatotoxicity
- Cholesterol Gallstones
1 min
Vitamin B3 - Niacin (Nicotinic Acid)
- Mechanism
- Decreases Triglycerides
- Decreases LDL
- Increases HDL
- Indications
- Dyslipidemia
- Pellagra
- Diarrhea
- Dermatitis
- Dementia
- Side Effects
- Flushing
- GI Distress
- Hepatotoxicity
2 mins
Statins
- Rhabdomyolysis
- Hepatotoxicity
- HMG-CoA reductase inhibitors
- Decrease LDL
- Decrease Triglycerides
- Increase HDL
2 mins
Aspirin (Acetylsalicylic Acid)
- Mechanism
- Inhibits Platelet Aggregation
- NSAID
- Indications
- Thrombotic Event Prevention
- General Pain
- Inflammatory Conditions
- Fever
- Side Effects
- Pancytopenia
- GI Ulcers
- Bleeding
- Considerations
- Withhold Before Surgery 7-10 Days
- Reye's Syndrome
2 mins
Warfarin (Coumadin)
- Mechanism of Action
- Inhibits Clotting Factors
- Indications
- Atrial Fibrillation
- Venous Thrombosis
- Pulmonary Embolism
- Assessment
- PT/INR Levels
- Observe for Bleeding
- Contraindications
- Pregnancy
- Nursing Considerations
- Vitamin K and Fresh Frozen Plasma
- Prolonged Therapeutic Onset
- Maintain Same Diet
2 mins
Heparin (Unfractionated)
- Mechanism of Action
- Suppresses Coagulation
- Indications
- Deep Vein Thrombosis (DVT)
- Pulmonary Embolism
- Side Effects
- Hemorrhage
- Heparin-Induced Thrombocytopenia (HIT)
- Considerations
- Monitor aPTT
- Preferred (Safe) During Pregnancy
- Antidote
- Protamine Sulfate
2 mins
Enoxaparin (Lovenox)
- Mechanism of Action
- Inhibits Clotting Factors
- Factor Xa
- Indications
- Clot Formation Prevention
- Side Effects
- Heparin Induced Thrombocytopenia (HIT)
- Bleeding
- Considerations
- Medication Education
- Subcutaneous Injection
- 2 Inches from Umbilicus or Incisions
- Antidote
- Protamine Sulfate
2 mins
Clopidogrel (Plavix)
- Mechanism
- ADP Receptor Antagonist
- Prevent Platelet Aggregation
- Indications
- Acute Coronary Syndrome (ACS)
- Prevention of Thrombotic Events
- Side Effects
- Bleeding
- Thrombotic Thrombocytopenic Purpura (TTP)
- Pancytopenia
- Abdominal Pain
- Considerations
- Withhold Before Surgery
2 mins
Ticlopidine (Ticlid)
- Mechanism
- ADP Receptor Antagonist
- Irreversibly Inhibits Platelet Aggregation
- Indications
- Thrombotic Event Prevention
- Side Effects
- Neutropenia
- Thrombotic Thrombocytopenic Purpura (TTP)
- GI Distress
- Rash
- Considerations
- Withhold Before Surgery
- Monitor Blood Count
2 mins
Alteplase
- Mechanism
- Tissue Plasminogen Activator
- Indications
- Thrombosis
- Side Effects
- Bleeding
- Contraindications
- Intracranial Hemorrhage
- Internal Hemorrhaging
- Considerations
- Minimize Bleeding
- Monitor for Shock
- Antidote
- Aminocaproic Acid
2 mins
Abciximab and Tirofiban (GP IIb/IIIa Inhibitors)
- Mechanism
- IIb/IIIa Receptor Inhibitors
- Inhibits Platelet Aggregation
- Indications
- Thrombotic Event Prevention
- Acute Coronary Syndrome (ACS)
- Percutaneous Coronary Intervention (PCI)
- Side Effects
- Bleeding
- Considerations
- Expensive
- Combination Drug Therapy
2 mins
Tamoxifen
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Antagonist on Breast Tissue
- Indications
- ER-positive Breast Cancer
- Side Effects
- Decreased Risk of Osteoporosis
- Increased Risk of Endometrial Cancer
- Increased Risk of Venous Thromboembolism (VTE)
1 min
Busulfan
- Indications
- CML
- Bone Marrow Ablation
- Mechanism
- Cross-Links DNA
- Side Effects
- Myelosuppression
- Pulmonary Fibrosis
- Hyperpigmentation
55 secs
Cisplatin (Platinol)
- Mechanism
- Alkylating Agent
- Cross-Links DNA
- Indications
- Testicular Cancer
- Ovarian Cancer
- Side Effects
- Nausea and Vomiting
- Myelosuppression
- Nephrotoxicity
- Ototoxicity
- Peripheral Neuropathy
- Considerations
- Antiemetics Before Administration
- Aggressive Hydration
3 mins
Vincristine (Oncovin)
- Mechanism
- Vinca Alkaloid
- Inhibits Microtubules
- Indications
- Leukemias
- Lymphomas
- Side Effects
- Peripheral Neuropathy
- Paralytic Ileus
- Considerations
- Vesicant
2 mins
Bleomycin
- Indications
- Testicular Cancer
- Hodgkin's Lymphoma
- Mechanism of Action
- Induces Free Radical Formation
- Breaks in DNA Strands
- Side Effects
- Pulmonary Fibrosis
- Skin Changes
- Mucositis
1 min
Hydroxyurea
- Mechanism
- Inhibits Ribonucleotide Reductase
- Decreased DNA Synthesis
- S-phase Specific
- Indications
- Melanoma
- Chronic Myelogenous Leukemia (CML)
- Sickle Cell Disease
- Through Increased HbF (Fetal Hemoglobin)
- Side Effects
- Myelosuppression
- GI Distress
2 mins
Cyclophosphamide
- Mechanism
- Requires Bioactivation by Liver
- Cross-links DNA
- Guanine N7 Position
- Indications
- Autoimmune Disorders
- Leukemia
- Lymphoma
- Solid Tumors
- Side Effects
- Myelosuppression
- Hemorrhagic Cystitis
- Prevent with Mesna
3 mins
Rituximab
- Indications
- Chronic Lymphocytic Leukemia (CLL)
- Non-Hodgkin Lymphoma
- Rheumatoid Arthritis
- Microscopic Polyangiitis (MPA)
- Granulomatosis with Polyangiitis (Formerly Wegener's)
- Mechanism
- Monoclonal Antibody Against CD20
- Found on B Cell Neoplasms
- Side Effects
- Infusion Reactions
- Skin and Mouth Reactions
- Reactivation of Hepatitis B Virus (HBV)
- Progressive Multifocal Leukoencephalopathy (PML)
3 mins
Silver Sulfadiazine (Silvadene) and Mafenide Acetate (Sulfamylon)
- Mechanism
- Topical Antimicrobial
- Indications
- Burns
- Open Wound Care
- Side Effects
- Mafenide
- Pain
- Acidosis
- Considerations
- Administer Analgesic Prior to Wound Care
1 min
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
Amphotericin B
- Indications
- Systemic Mycosis
- Fungal Meningitis
- Last Resort for Protozoan infections
- Mechanism
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
1 min
Amphotericin B Side Effects & Toxicity
- Side Effects
- Fever/Chills "Shake and Bake"
- Nephrotoxicity
- Milder with Liposomes
- Hypotension
- Anemia
- IV Phlebitis
- Arrhythmias
1 min
Flucytosine
- Indications
- Cryptococcus
- Candida
- Used in Combination with Amphotericin B or Azoles
- Mechanism
- Inhibits DNA and RNA Synthesis
- Converted to 5-FU by Cytosine Deaminase
- Side Effects
- Bone Marrow Suppression
1 min
Griseofulvin
- Mechanism
- Disrupts Microtubules in Mitosis
- Indications
- Antifungal for Superficial Infections
- Tinea and Ringworm
- Side Effects
- Teratogen
- P450 Inducer
- Confusion
- Headache
2 mins
Terbinafine
- Indications
- Dermatophytosis
- Onychomycosis
- Mechanism
- Inhibits Squalene Epoxidase
- Side Effects
- Hepatotoxicity
- GI Distress
- Taste Disturbances
- Headache
2 mins
Echinocandins
- "-Fungin" Suffix
- Indications
- Invasive Aspergillosis
- Candida
- Mechanism
- Inhibits Cell Wall Synthesis
- Inhibits Synthesis of Beta-glucan
- Side Effects
- GI Distress
- Flushing
1 min
Nystatin
- Indications
- Candidiasis
- Vaginal
- Oral
- Cutaneous
- Mechanism
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
- Topical form of Amphotericin B
- Side Effects
- Rash
1 min
NSAIDs
- Indications
- Anti-inflammatory
- Analgesic
- Fever
- Closure of Patent Ductus Arteriosus
- Mechanism of Action
- Reversible Inhibition of COX-1 and COX-2
- Block Prostaglandin Synthesis
- Side Effects
- Interstitial Nephritis
- Gastric Ulcer
- Renal Ischemia
1 min
Reye's Syndrome
- Cause
- Aspirin (Salicylates) to Treat Viral Illness (In Children)
- Assessment
- Cerebral Edema
- Lethargy (Decreased LOC)
- Vomiting
- Liver Failure
- Interventions
- Monitor for Increased ICP
- Mannitol (Osmitrol)
- Considerations
- No Aspirin for Children
2 mins
Ibuprofen (Advil, Motrin)
- Mechanisms
- NSAID
- COX Inhibitor
- Indications
- General Pain
- Fever
- Inflammatory Conditions
- Side Effects
- GI Ulcers
- Nephrotoxicity
- Rash
- Considerations
- Avoid with Alcohol
- Risk of Thrombotic Event
2 mins
Prednisone (Glucocorticoids)
- Mechanism
- Glucocorticoid
- Indications
- Inflammatory Conditions
- Organ Transplant Rejection
- Side Effects
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Considerations
- Adrenal Insufficiency
- Taper Gradually
2 mins
Acetaminophen
- Indications
- Fever
- Pain
- Mechanism of Action
- Reversibly Inhibits COX
- Acts Primarily in CNS
- Side Effect
- Hepatic Necrosis
- N-acetylcysteine Antidote
51 secs
Celecoxib
- Indications
- Rheumatoid Arthritis
- Osteoarthritis
- Pain
- Mechanism of Action
- NSAID
- Selectively Inhibits COX-2
- Side Effects
- Sulfa Allergy
- Increased Risk of Thrombosis
- GI Bleed
- Contraindication
- Pregnancy > 30 Weeks
1 min
Opioids Overview
- Indications
- Pain
- Weaning
- Cough
- Diarrhea
- Mechanism of Action
- Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
- Decrease Synaptic Transmission
- Side Effects
- Respiratory Depression
- Addiction
- Miosis
- Constipation
2 mins
Opioid Use Disorder and Withdrawal Assessment (Formerly Opioid Abuse and Withdrawal Assessment)
- Abuse Assessment
- Euphoria
- Miosis
- CNS Depression
- Abuse Withdrawal
- Yawning
- Gooseflesh
- Sweating
- Rhinorrhea
- Kicking Movements
- Consideration
- Naloxone
1 min
Alendronate (Fosamax)
- Mechanism
- Inhibits Osteoclasts
- Indications
- Osteoporosis
- Paget's Disease
- Side Effects
- Esophageal Ulcers
- Musculoskeletal Pain
- Vision Changes
- Atrial Fibrillation
- Osteonecrosis of the Jaw
- Considerations
- Take on Empty Stomach
- Remain Upright
2 mins
Hydroxychloroquine
- Mechanism of Action
- Immunosuppressant
- Indications
- Malaria
- Rheumatoid Arthritis
- Systemic Lupus Erythematosus (SLE)
- Porphyria Cutanea Tarda
- Side Effects
- Cardiotoxicity
- Retinopathy
- Considerations
- Ophthalmological Exams
3 mins
Raloxifene
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Agonist in Bone
- Antagonist in Breast and Uterus
- Indications
- Osteoporosis
- Breast Cancer Prophylaxis
- Uterine Fibroids
- Side Effects
- Hot Flashes
- Thromboembolism
2 mins
Mannitol (Osmitrol)
- Mechanism
- Osmotic Diuresis
- Indications
- Reducing Intracranial Pressure
- Reducing Intraocular Pressure
- Renal Failure Prophylaxis
- Side Effects
- Edema
- Fluid and Electrolyte Imbalance
- Considerations
- Avoid Use in Cardiac Patients
- IV Administration
2 mins
Loop Diuretics
- Mechanism of Action
- Thick Ascending Limb of Loop of Henle
- Inhibits Na+-K+-2Cl-
- Sulfa Drug
- Drug Names
- Furosemide
- Lasix
- Side Effects
- Ototoxicity from Rapid Injection
- Gout
- Dehydration
- Hypocalcemia
- Hypokalemia
- Orthostatic Hypotension
2 mins
Loop Diuretic Education
- Furosemide (Lasix)
- Indications
- Heart Failure
- Pulmonary Edema
- Acute Renal Failure (ARF)
- Edema
- Education
- Notify the provider of weakness, dizziness, or muscle cramping
- Increase Potassium Intake
- Check BP Daily
- Daily Weights and Monitor IandOs
1 min
Ethacrynic Acid
- Mechanism of Action
- Non-sulfa Drug
- Phenoxyacetic Acid Derivative
- Loop Diuretic
- Inhibits Na+-K+-2Cl- Cotransporter
- Thick Ascending Loop of Henle
- Clinical Use
- Diuresis
- Side Effects
- Hypokalemia
- Ototoxicity
- Gout
2 mins
Hydrochlorothiazide HCTZ
- Mechanism of Action
- Inhibits Reabsorption NaCl and H2O
- Indications
- Edema
- Mild to Moderate Hypertension
- Side Effects
- Hypokalemia
- Hyponatremia
- Dehydration
- Hyperglycemia
- Gout
- Contraindications
- Sulfa Allergy
- Pregnancy and Breastfeeding
1 min
Spironolactone (Aldactone)
- Mechanisms
- Inhibition of Aldosterone
- Potassium Retention
- Indications
- Hypertension
- Edema
- Heart Failure
- Side Effects
- Hyperkalemia
- Endocrine Effects
- Consideration
- Avoid Potassium Supplements
2 mins
Erythropoietin
- Mechanism
- Stimulates RBC Production
- Indications
- Chronic Renal Failure
- Anemia
- Side Effects
- Increased Risk of Thrombosis
- Pelvic and Limb Pain
- Hypertension
- Considerations
- Do Not Shake
- Monitor Hemoglobin (Hgb) Weekly
- May Accelerate Tumor Progression
2 mins
Insulin
- Rapid Acting
- Insulin Lispro (Humalog)
- Insulin Aspart (Novolog)
- Insulin Glulisine (Apidra)
- Short Acting
- Regular Insulin (Humulin R)
- Intermediate Acting
- Isophane NPH (Humulin N)
- Long Acting
- Detemir (Levemir)
- Glargine (Lantus)
2 mins
Metformin (Glucophage)
- Mechanism
- Decrease Glucose Production
- Increase Insulin Sensitivity
- Indications
- Type 2 Diabetes
- Polycystic Ovary Syndrome (PCOS)
- Side Effects
- GI Distress
- Decreased Appetite
- Lactic Acidosis
- Considerations
- IV Contrast
- Limit Alcohol Consumption
2 mins
Mixing NPH and Regular Insulin for Injection
- Verify Order
- Roll NPH Insulin
- Alcohol to Multiuse Vials
- Inject Air into NPH Insulin (Cloudy)
- Inject Air into Regular Insulin (Clear)
- Withdraw Regular Insulin Units
- Withdraw NPH Units
- Verify with 2nd Nurse
- Discard if Error
3 mins
Chlorpropamide and Tolbutamide (Orinase) (1st Generation Sulfonylureas)
- Mechanisms
- 1st Generation Sulfonylureas
- Stimulate Release of Insulin
- Indications
- Type 2 Diabetes
- Side Effects
- Hypoglycemia
- Possible Cardiovascular Toxicity
- Weight Gain
- Considerations
- Exacerbated Hypoglycemia with Beta-blockers
- Avoid During Pregnancy and Breast Feeding
- Avoid Alcohol
2 mins
Glyburide and Glipizide (2nd Generation Sulfonylureas)
- Mechanisms
- 2nd Generation Sulfonylureas
- Blocks Potassium Channels in Beta Cells
- Stimulate Release of Insulin
- Indications
- Type 2 Diabetes
- Side Effects
- Hypoglycemia
- Considerations
- More Potent
- Beta Blockers Reduce Effects
- Avoid Alcohol
- Avoid Breastfeeding
2 mins
Pioglitazone (Thiazolidinediones)
- -glitazones Suffix
- Mechanism
- Binds PPAR-Gamma
- Decreases Insulin Resistance
- Indications
- Type 2 Diabetes
- Side Effects
- Weight Gain
- Heart Failure
- Myalgia
- Hypoglycemia
- Upper Respiratory Infection
- Considerations
- Increased Risk of Bladder Cancer
- Increased Fracture Risk in Women
- Monitor Liver Enzymes
2 mins
Acarbose (Precose) and Miglitol (Glyset) (Alpha Glucosidase Inhibitors)
- Mechanisms
- Alpha Glucosidase Inhibitors
- Delays Absorption of Carbohydrates
- Indications
- Type 2 Diabetes
- Side Effects
- Flatulence
- Diarrhea
- Anemia
- Cramps
- Considerations
- Monitor LFTs
- Oral Glucose for Hypoglycemia
2 mins
Repaglinide and Nateglinide (Meglitinides)
- Mechanisms
- Meglitinides
- Increased Insulin Release
- Indications
- Type 2 Diabetes
- Side Effect
- Hypoglycemia
- Considerations
- Eat Within 30 Minutes
- Gemfibrozil Increases Risk of Hypoglycemia
- Short Half-Life
2 mins
Sitagliptin (Januvia) and Saxagliptin (Onglyza) (DPP-4 Inhibitors)
- -gliptin Suffix
- Mechanisms
- DPP-4 Inhibitor
- Increases Insulin Release
- Indications
- Type 2 Diabetes
- Side Effects
- Pancreatitis
- Upper Respiratory Infection and Inflammation
- Stevens-Johnson Syndrome
- Considerations
- Used as Add-on Agents
2 mins
Pramlintide (Symlin)
- Mechanism
- Synthetic Amylin Analog
- Indications
- Diabetes Type 1 and 2
- Supplement Mealtime Insulin
- Side Effects
- Nausea
- Skin Reactions at Injection Site
- Considerations
- Hypoglycemia When Combined with Insulin
- Delayed Absorption of Oral Drugs
2 mins
Exenatide (Byetta)
- Mechanism
- Incretin Mimetic
- GLP-1 Synthetic Analog
- Indications
- Type 2 Diabetes
- Side Effects
- Hypoglycemia
- Nausea and Vomiting
- Diarrhea
- Thyroid Cancer
- Pancreatitis
- Renal Failure
- Considerations
- (Give Exenatide) One Hour After Other Medications
- Adjunct Therapy
3 mins
Glucagon (GlucaGen)
- Mechanism
- Increases Glucose
- Indications
- Hypoglycemic Emergency
- Side Effects
- Nausea and Vomiting
- Considerations
- Reconstitute Powder
- Consume Oral Carbohydrates
- 50% Dextrose IV (If No Effect)
2 mins
Levothyroxine (Synthroid)
- Mechanism
- Synthetic T4
- Indications
- Hypothyroidism
- Side Effects
- Thyrotoxicosis
- Tremors
- Heat Intolerance
- Insomnia
- Tachycardia
- Considerations
- Do Not Use for Obesity
- TSH Monitoring
2 mins
Propylthiouracil (PTU) and Methimazole (MMI)
- Indications
- Hyperthyroidism
- Mechanism
- Inhibits Thyroid Peroxidase
- PTU Blocks Peripheral Conversion of T4 to T3
- Side Effects
- Agranulocytosis
- Skin Rash
- Hepatotoxicity (PTU)
- Teratogen (MMI)
1 min
Tacrolimus (Prograf) Overview
- Mechanisms
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Transplant Rejection
- Atopic Dermatitis
- Considerations
- Increased Lymphoma Risk
- Avoid Grapefruit Juice
1 min
Tacrolimus (Prograf) Side Effects
- Nephrotoxicity
- Neurotoxicity
- GI Distress
- Infection
- Hypertension
- Hyperkalemia
- Hyperglycemia
1 min
Cyclosporine (Sandimmune) Overview
- Mechanism
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Prevent Transplant Rejection
- Psoriasis
- Rheumatoid Arthritis
- Considerations
- Monitor Plasma Levels
- Avoid Grapefruit Juice
- Increased Risk of Lymphoma
2 mins
Cyclosporine (Sandimmune) Side Effects
- Side Effects
- Nephrotoxicity
- Hepatotoxicity
- Infection
- Hypertension
- Hirsutism
- Tremor
- Hyperkalemia
- Hypomagnesemia
- Gingival Hyperplasia
1 min
Methotrexate
- Indications
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Mechanism
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Side Effects
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
2 mins
Omeprazole (Prilosec)
- "-prazole" Suffix
- Indications
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Mechanism
- Proton Pump Inhibitor (PPI)
- Inhibit H+/K+/ATPase
- Side Effects
- Hip Fracture
- Pneumonia
2 mins
Cimetidine and Famotidine (H2 Receptor Blockers)
- -tidine Suffix
- Mechanism
- H2 Receptor Blocker
- Indications
- Suppress Gastric Acid Secretion
- Side Effects (All)
- Pneumonia
- Side Effects - Cimetidine
- Anti-androgen Effects
- CNS Changes
2 mins
Pancreatin, Pancrelipase (Pancreatic Enzymes)
- Mechanism
- Pancreatic Enzymes
- Indications
- Cystic Fibrosis
- Pancreatic Insufficiency
- Side Effects
- GI Distress
- Considerations
- Inactivated by Gastric Acid
- 24 Hour Fat Excretion
- Take with Every Meal and Snack
2 mins
Sucralfate (Carafate)
- Mechanism
- Creates Protective Barrier
- Indications
- GI Ulcers
- Side Effects
- Constipation
- Considerations
- Require Acidic Environment
- Give on Empty Stomach
- Oral Suspension Available
- May Decrease Absorption of Other Meds
2 mins
Activated Charcoal (Actidose)
- Mechanism
- Binds to Toxins
- Indications
- Ingested Poison
- Side Effects
- Black Stool
- GI Distress
- Considerations
- Give As Soon As Possible
- Via Mouth or NG Tube
- Gastric Lavage
- Do Not Administer with Antidotes
2 mins
Promethazine (Phenergan)
- Mechanism
- Histamine H1 Receptor Antagonist
- Weak Dopamine Antagonist
- Indications
- Nausea and Vomiting
- Motion Sickness
- Side Effects
- Respiratory Depression
- Sedation
- Anticholinergic Effects
- Extrapyramidal Symptoms
- Considerations
- Use Large Bore IV
- Monitor for Tissue Necrosis
2 mins
Ondansetron
- Indications
- Postoperative Vomiting
- Chemotherapy-induced Nausea and Vomiting
- Mechanism
- 5-HT3 Serotonergic Antagonist
- Centrally-acting Antiemetic
- Side Effects
- Headache
- Constipation
- QT Prolongation
1 min
Osmotic Laxatives
- Mechanism of Action
- Increases Osmotic Load
- Indications
- Hepatic Encephalopathy
- Constipation
- Drugs
- Magnesium Hydroxide
- Magnesium Citrate
- Polyethylene Glycol
- Sorbitol
- Lactulose
- Side Effects
- Diarrhea
- Dehydration
- Considerations
- Misused in Bulimia Nervosa
2 mins
Metoclopramide
- Indications
- Antiemetic
- Promotility Agent
- Mechanism
- Increased Resting Tone
- Antagonist at D2 Receptor
- Side Effects
- Parkinsonian Symptoms
- Galactorrhea
- Contraindication
- Small Bowel Obstruction
- Parkinson's Disease
2 mins
Proton Pump Inhibitors (PPIs)
- "-prazole" Suffix
- Indications
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Mechanism
- Inhibit H+/K+/ATPase
- Side Effects
- Hip fracture
- Pneumonia
2 mins
Orlistat
- Mechanism
- Inhibits Gastric and Pancreatic Lipase
- Decrease Absorption of Fat
- Clinical Use
- Weight Loss
- Side Effects
- Increased Bowel Movements
- Steatorrhea
- Abdominal Pain
- Flatulence
- Calcium Oxalate Kidney Stones
- Decreased Absorption of Fat-Soluble Vitamins
2 mins
Hepatitis C Pharmacotherapy
- NS3/4A Inhibitors
- Glecaprevir
- Grazoprevir
- Simeprevir
- NS5A Inhibitors
- Ledipasvir
- Elbasvir
- Velpatasvir
- NS5B Inhibitors
- Sofosbuvir
- RNA Polymerase Inhibitor
- Ribavirin
2 mins
Vitamin A (Retinol)
- Mechanism
- Maintains Mucous Membranes
- Eyes and Skin
- Indications
- Dietary Deficiency
- Skin Disorders
- Side Effects
- Hepatosplenomegaly
- Jaundice
- Increased ICP
- Vomiting
- Considerations
- Teratogen
- Animal Food Products
- Dark Green and Orange Fruits/Vegetables
2 mins
Vitamin B1 (Thiamine)
- Mechanism
- Carbohydrate Metabolism
- Indications
- Dietary Deficiency
- Beriberi
- Wernicke-Korsakoff
- Considerations
- Alcoholics Highest Risk
- Give Before Glucose
- Give IM or IV
- Enriched Whole Grains
- Pork
2 mins
Beriberi (Thiamine Deficiency)
- Mechanism
- Thiamine Deficiency
- Assessment
- Dry Beriberi
- Polyneuritis
- Muscle Wasting
- Wet Beriberi
- Dilated Cardiomyopathy
- Edema
2 mins
Vitamin B6 (Pyridoxine)
- Mechanism
- Amino Acid and Protein Metabolism
- Heme Synthesis
- Neurotransmitters
- Indications
- Adjunct to Isoniazid
- Dietary Deficiency
- Premenstrual Syndrome (PMS)
- Side Effects
- Ataxia
- Peripheral Neuropathy
- Contraindications
- Levodopa
- Considerations
- Cereals and Meats
3 mins
Cobalamin (Vitamin B12)
- Mechanism
- Vitamin B12
- Indications
- Vitamin Deficiency
- Pernicious Anemia
- Side Effects
- Hypokalemia
- Arthralgia
- Dizziness
- Considerations
- IM Injection for Pernicious Anemia
- Never Give IV
2 mins
Vitamin C (Ascorbic Acid)
- Mechanism
- Antioxidant
- Collagen Formation
- Steroid Synthesis
- Indications
- Dietary Deficiency
- Scurvy
- Side Effects
- GI Distress
- Considerations
- Citrus Fruits
- May Improve Healing
2 mins
Ergocalciferol (Vitamin D2)
- Mechanism
- Vitamin D2
- Indications
- Hypoparathyroidism
- Rickets
- Hypophosphatemia
- Side Effects
- Fatigue
- Constipation
- Hypercalcemia
- Kidney Stones
2 mins
Vitamin E (Alpha-tocopherol)
- Mechanism
- Antioxidant
- Indications
- Fat Malabsorption Syndrome
- Alpha-TTP Deficiency
- Side Effects
- Bleeding
- Considerations
- Increased Risk Hemorrhagic Stroke
- Limit Doses < 200 IU per Day
- Nuts and Whole Grains
- Vegetable Oils
2 mins
Vitamin K1 (Phytonadione)
- Mechanism
- Synthesizes Clotting Factors II, VII, IX, X
- Indications
- Hypoprothrombinemia
- Newborn Prophylaxis
- Bleeding from Warfarin Overdose
- Side Effects
- Shock
- Kernicterus
- Cardiac Arrest
- Considerations
- Bile Salts required for Intestinal Absorption
- Increased Risks with IV Administration
2 mins
Iron (Ferrous Sulfate)
- Mechanism
- Ferrous Salts
- Indications
- Anemia
- Side Effects
- GI Distress
- Nausea and Vomiting
- Dark Stools
- Considerations
- Take Between Meals
- Liquid can Stain Teeth
- Keep out of Reach from Children
- Caution with GI Disorders
- Avoid Antacids
3 mins
Total Parenteral Nutrition (TPN)
- Mechanism
- Nutrition Given Outside GI
- Side Effects
- Hyperglycemia
- Hyperlipidemia
- Refeeding Syndrome
- Nausea and Vomiting
- Considerations
- Slow IV Infusion
- Use Large Central Vein
- No Added Meds to TPN Line
2 mins
Cholecalciferol (Vitamin D3)
- Mechanism
- Vitamin D3
- Indications
- Dietary Supplement
- Vitamin D Deficiency
- Side Effects
- Fatigue
- Constipation
- Hypercalcemia
- Kidney Stones
- Considerations
- More Effective Than Ergocalciferol
- Hypervitaminosis D
2 mins
Vitamin D Deficiency
- Signs & Symptoms
- Rickets in children
- Bending bones
- Rachitic rosary
- Breast milk has decreased vitamin D
- Osteomalacia in adults
- Tetany from Hypocalcemia
2 mins
RhoGam [Rho(D) Immune Globulin]
- Indications
- Antepartum Prevention at 28 weeks
- Suppress Antibody Production
- Mechanism of Action
- Lysis of Fetal RBC in Maternal Bloodstream
- Side Effects
- Myalgia and Lethargy
- Considerations
- Negative Coombs Test
- Standard Dose 300 mcg
- Microdose 50 mcg
- Blood Product
2 mins
Isoniazid
- Indications
- Tuberculosis (TB)
- Mechanism of Action
- Requires Catalase Peroxidase
- Decreases Mycolic Acid Synthesis
- Fast vs Slow Acetylators
- Side Effects
- B6 Deficiency
- Neurotoxicity
- Hepatotoxicity
- Drug-induced Lupus
1 min
Leuprolide
- Mechanism
- GnRH Agonist (Pulsatile Use)
- GnRH Antagonist (Continuous Use)
- Upregulates FSH And LH
- Downregulates FSH And LH
- Indications Pulsatile
- Infertility
- Indications Continuous
- Prostate Cancer
- Precocious Puberty
- Uterine Fibroids
- Endometriosis
- Side Effects
- Anti-androgenic Effects
2 mins
Macrolides
- Mechanism of Action
- Bacteriostatic
- Bind to 23S rRNA of 50S Subunit
- Inhibit Protein Synthesis by Blocking Translocation
- Macrolides
- Erythromycin
- Azithromycin
- Clarithromycin
- Indications
- Gram-Positive Cocci
- Atypical Pneumonia
- Chlamydia
- Considerations
- Resistance by Methylation of 23S rRNA Binding
2 mins
Methylergonovine (Methergine) and Ergotamine (Ergot Alkaloids)
- Mechanism
- Smooth Muscle Contraction
- Vasoconstriction
- Indications
- Migraine
- Postpartum Hemorrhage
- Side Effects
- Nausea and Vomiting
- Severe Hypertension
- Tachycardia
- Considerations
- 2nd Line Agent
2 mins
Ethambutol
- Mechanism of Action
- Bacteriostatic
- Blocks Arabinosyltransferase
- Arabinosyltransferase Polymerizes Carbohydrates
- Carbohydrate Polymers Make Mycobacterium TB Cell Wall
- Side Effects
- Red/Green Color Blindness
- Reversible with Drug Discontinuation
40 secs
Oxytocin (Pitocin)
- Mechanism of Action
- Increase Uterine Contractions
- Indications
- Labor Induction
- Control Postpartum Hemorrhage
- Side Effects
- Uterine Rupture
- Water Intoxication
- Contraindications
- Fetal Lung Immaturity
- Cervix Not Ripened
- Active Genital Herpes Infection
- Considerations
- Use Lowest Dose
- IV Pump
3 mins
Rifampin
- Tuberculosis (TB)
- Blocks RNA Polymerization
- Haemophilus influenzae Type B
- Leprosy
- Meningitis
- P450 inducer
- Red-orange urine
55 secs
Carboprost (Hemabate)
- Mechanism
- Prostaglandin F2-alpha Analog
- Smooth Muscle Contraction
- Indications
- Postpartum Hemorrhage
- Abortion
- Side Effects
- GI Distress
- Hypertension
- Fever
- Bronchoconstriction
- Considerations
- Identify Cause of Fever
2 mins
Foscarnet
- Indications
- CMV Retinitis
- Acyclovir-resistant HSV
- Mechanism
- Does Not Require Activation (by Viral Kinase)
- Inhibits Viral DNA Polymerase
- Pyrophosphate Analog
- Resistance through Mutated DNA Polymerase
- Side Effects
- Nephrotoxicity
- Electrolyte Abnormalities
- Hypokalemia
- Hypocalcemia
- Hypomagnesemia
2 mins
Dinoprostone and Misoprostol
- Mechanism
- Prostaglandins
- Indications
- Promote Cervical Ripening
- Prevent GI Ulcers
- Medical Abortion
- Side Effects
- Fetal Distress
- Hyperstimulation of Uterus
- Considerations
- Vaginal Insertion
- Give Before Induction of Labor
2 mins
Ganciclovir
- Indications
- Cytomegalovirus (CMV)
- Immunocompromised
- Mechanism
- Guanosine Analog
- Disrupts DNA Synthesis
- Inhibits Viral DNA Polymerase
- Side Effects
- Hematologic Effects
- Nephrotoxicity
1 min
Terbutaline (Brethine)
- Mechanism of Action
- Beta-2 Agonists
- Indications
- Asthma
- Tocolytic
- Side Effects
- Hypotension
- Tremor
- Tachycardia
- Pulmonary Edema
- Hyperglycemia
2 mins
Clomiphene
- Indications
- Infertility
- Polycystic Ovarian Syndrome (PCOS)
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Hypothalamus
- Estrogen Antagonist
- Increased GnRH, LH and FSH Secretion
- Induction of Ovulation
- Side Effects
- Multiple Gestations
- Visual Disturbances
- Hot Flashes
2 mins
Posterior Column (Dorsal Column)
- Ascending Pathway (Sensory)
- Sensations
- Proprioception
- Fine Touch
- Pressure
- Vibration Sensation
- Anatomy
- Dorsal Root
- Fasciculus Cuneatus
- Arms
- Fasciculus Gracilis
- Lower Limbs
- Lesions
- Vitamin B12 Deficiency
- Tabes Dorsalis
2 mins
Beta-2 Agonists
- Short-term Treatment
- Terbutaline
- Asthma
- Tocolysis
- Albuterol
- Asthma
- Long-term Treatment
- Salmeterol
- Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
3 mins
NRTIs (Nucleoside Reverse Transcriptase Inhibitors)
- Indications
- HIV
- Pregnancy and Prophylaxis given ZDV
- Mechanism
- Inhibit Nucleotide Binding to Reverse Transcriptase
- Chain Termination
- Require Phosphorylation
1 min
Albuterol (Proventil)
- Mechanism
- Short-Acting Beta-2 Agonist
- Indications
- Bronchospasm
- Asthma
- Side Effects
- Angina
- Tachycardia
- Tremor
1 min
Cromolyn (Mast Cell Stabilizers)
- Mechanism
- Mast Cell Stabilizer
- Indications
- Asthma Prophylaxis
- Bronchial Inflammation
- Allergic Rhinitis
- Side Effects
- Cough
- Bronchospasm
- Consideration
- Fixed Schedule Administration
2 mins
Theophylline (Theo-24)
- Mechanism
- Bronchial Smooth Muscle Relaxation
- Indications
- Asthma
- Side Effects
- Insomnia
- Restlessness
- Arrhythmias
- Seizures
- Considerations
- Narrow Therapeutic Range
- Monitor Plasma Levels
1 min
Cidofovir
- Indications
- CMV Retinitis
- Acyclovir-Resistant HSV
- Mechanism
- Inhibits Viral DNA Polymerase
- Side Effects
- Nephrotoxicity
- Administer with Probenecid and IV Saline
1 min
Montelukast (Singulair)
- Mechanism
- Leukotriene Receptor Blocker
- Indications
- Allergic Rhinitis
- Asthma Prophylaxis
- Exercise Induced Bronchospasm
- Side Effects
- Fatigue
- Headache
- Mood Changes
- Suicidal Thoughts
- Considerations
- Increased Risk of Churg Strauss
2 mins
Zanamivir (Relenza) and Oseltamivir (Tamiflu)
- Indications
- Influenza A and B
- Treatment and Prophylaxis
- Mechanism
- Inhibits Release of New Virus
- Inhibits Influenza Neuraminidase
1 min
NRTI Toxicity
- Bone Marrow Suppression
- Reverse with G-CSF and Erythropoietin
- Rash
- Neuropathy
- Anemia
- Pancreatitis
- Lactic Acidosis
1 min
Second Generation Antihistamines
- Indications
- Allergies
- Mechanism of Action
- Lipophobic
- Histamine H1 Receptor Antagonist
- Drugs
- Azelastine + Fluticasone (Dymista)
- Intranasal Spray
- Cetirizine (Zyrtec)
- Loratadine (Claritin)
- Fexofenadine (Allegra)
- Considerations
- Fewer Anticholinergic Effects
- Fewer CNS Effects
2 mins
NNRTIs (Non-nucleoside Reverse Transcriptase Inhibitors)
- Indications
- HIV
- Mechanism
- Do Not Require Intracellular Metabolism
- Inhibits Reverse Transcriptase
- Side Effects
- Rash
- Hepatotoxicity
- Vivid Dreams and CNS Symptoms
- Contraindication
- Pregnancy
2 mins
First Generation Antihistamines
- Mechanism of Action
- Histamine H1 Receptor Antagonist
- Indications
- Allergies
- Nausea and Vomiting
- Motion Sickness
- Anaphylaxis
- Drug Names
- Diphenhydramine (Benadryl)
- Promethazine (Phenergan)
- Chlorpheniramine
- Side Effects
- Sedation
- Anticholinergic Effects
2 mins
Stages of Asthma Treatments
- Mild Intermittent
- Short-acting Inhaled Beta-Agonist
- Mild Persistent
- Low-Dose Inhaled Corticosteroid
- Montelukast (Leukotriene Receptor Antagonist)
- Moderate Persistent
- Low to Medium-dose Inhaled Corticosteroid
- Zileuton
- Severe Persistent
- High-Dose Inhaled Corticosteroid
- Systemic Corticosteroids
- Omalizumab (Allergies)
2 mins
Isoniazid (INH)
- Mechanism
- Interferes with DNA Metabolism
- Indications
- Tuberculosis (TB)
- Side Effects
- Optic Neuritis
- Nausea and Vomiting
- Hepatotoxicity
- Peripheral Neuropathy
- Considerations
- Vitamin B6 Prophylaxis
- Monitor AST/ALT
2 mins
Ethambutol (Myambutol)
- Mechanisms
- Inhibits RNA Synthesis
- Bacteriostatic
- Indications
- Tuberculosis (TB)
- Side Effects
- Optic Neuritis
- Red/Green Color Blindness
- Gouty Arthritis
- Consideration
- Monitor Vision Acuity
2 mins
Antibiotics Overview
- Cell Wall Inhibitors
- Cell Wall Inhibitors
- Penicillins
- Cephalosporins
- Monobactams
- Carbapenems (Imipenem & Meropenem)
- Beta-Lactamase Inhibitors
- Protein Synthesis Inhibitors
- Protein Synthesis Inhibitors
- Aminoglycosides
- Macrolides
- Clindamycin
- Tetracyclines
- Linezolid
- Chloramphenicol
- Other
- Fluoroquinolones
- Sulfonamides
4 mins
Penicillin
- Mechanism of Action
- Weakens Cell Wall
- Indications
- Gram-Positive Infections
- Prophylaxis
- Side Effects
- Pain at IM Injection Site
- Allergic Reaction
- Considerations
- Skin Tests
- Allergy ID
- Medication Education
2 mins
Alpha 1 Receptor
- Characteristics
- Gq Subunit
- Increase Vascular Smooth Muscle Contraction
- Increase Pupillary Dilator Muscle Contraction
- Increase Intestinal and Bladder Sphincter Muscle Contraction
1 min
Alpha 2 Receptor
- Characteristics
- Gi Subunit
- Decrease Sympathetic Outflow
- Decrease Insulin Release
- Decrease Lipolysis
- Increase Platelet Aggregation
- Decrease Aqueous Humor Production
2 mins
Beta-1 Receptor
- Characteristics
- Gs Protein Class
- Increased Heart Rate
- Increased Contractility
- Increase Renin Release
- Increased Lipolysis
44 secs
Beta-2 Receptor
- Characteristics
- Gs Protein Class
- Cardiopulmonary
- Increased Heart Rate
- Increased Contractility
- Bronchodilation
- Metabolic
- Increased Lipolysis
- Increased Insulin
- Increased Glycogenolysis
- Increased Cellular Potassium Uptake
- Considerations
- Increased Aqueous Humor Production
- Vasodilation
- Decrease Uterine Tone
2 mins
P450 Inhibitors
- Quinidine
- Ciprofloxacin
- Isoniazid
- Grapefruit Juice
- Acute Alcohol Use
- Erythromycin (Macrolide)
- Indinavir
- Cimetidine
- Sulfonamides
- Ketoconazole
- Amiodarone
2 mins
P450 Inducer
- Griseofulvin
- Phenytoin
- Carbamazepine
- Rifampin
- Barbiturates
- Chronic Alcohol Use
- St. John's Wort
51 secs
Ampicillin and Amoxicillin
- Mechanism
- Aminopenicillin
- Broad Spectrum Penicillin
- Indications
- Gram-Positive and Some Gram-Negative Infections
- Side Effects
- Rash
- Diarrhea
- Considerations
- No Effect Against Staph Aureus
- Often combined with Beta Lactamase Inhibitor
- Allergic Reaction
2 mins
Pediatric Vaccinations - Age 2 Months
- 2 B DR HIP
- Hepatitis B
- DTaP - Diphtheria Tetanus acellular Pertussis
- RV - Rotavirus
- HiB - Haemophilus Influenzae Type B
- IPV - Inactivated Polio Vaccine
- PCV - Pneumococcal
1 min
Aztreonam (Azactam)
- Mechanism
- Monobactam Antibiotic
- Bactericidal
- Indications
- Gram-Negative Infections
- No Activity on Gram-Positives or Anaerobes
- Side Effects
- Blood Dyscrasias
- Pain at Injection Site
- Considerations
- Safe for Penicillin Allergy
- Synergistic with Aminoglycosides
- Nebulizer Form Available
2 mins
Pediatric Vaccinations - Age 4 Months
- 4 DR HIP
- DTaP - Diphtheria Tetanus acellular pertussis
- RV - Rotavirus
- HiB - Haemophilus Influenzae Type B
- IPV - Inactivated Polio Vaccine
- PCV - Pneumococcal
1 min
Cephalosporins
- Starts with "Cef-"
- Mechanism of Action
- Bactericidal
- Indications
- Gram-Positive and Gram-Negative Infections
- Side Effects
- Allergic Reactions
- Thrombophlebitis
- Bleeding
- Contraindications
- Renal Impairment
- Considerations
- Avoid IV Calcium with Ceftriaxone
- No Alcohol
2 mins
Pediatric Vaccinations - Age 6 Months
- B DR HIP In 6 Months
- Hepatitis B
- DTaP - Diphtheria Tetanus acellular pertussis
- RV - Rotavirus
- HiB - Haemophilus Influenzae Type B
- IPV - Inactivated Polio Vaccine
- PCV - Pneumococcal
- Influenza
2 mins
Imipenem and Meropenem (Carbapenems)
- Mechanism
- Carbapenems
- Broad-spectrum Antibiotic
- Bactericidal
- Indications
- Gram Positive and Gram Negative Infections
- Side Effects
- GI Distress
- Suprainfections
- Seizures
- Considerations
- Penicillin Allergy
- IV or IM Route
- Imipenem Combined with Cilastatin
3 mins
Pediatric Vaccinations - Age 12 to 15 Months
- 1 Very MAD HIP-ster
- Varicella Zoster
- MMR
- Hepatitis A
- DTaP - Diphtheria Tetanus acellular pertussis
- HiB - Haemophilus Influenzae Type B
- IPV - Inactivated Polio Vaccine
- PCV - Pneumococcal
2 mins
Macrolides
- End in "-thromycin"
- Mechanism of Action
- Bacteriostatic
- Indications
- Alternative for Penicillin Allergy
- Respiratory Infections
- Pneumonia
- Side Effects
- QT Prolongation and Sudden Death
- C.Diff Overgrowth
- GI Distress
- Considerations
- Slow IV Infusion
2 mins
Pediatric Vaccinations Age 4-6 Years
- Very DIM between 4-6pm
- Varicella Zoster
- DTaP - Diphtheria Tetanus acellular pertussis
- IPV - Inactivated Polio Vaccine
- MMR
1 min
Macrolides Side Effects
- Side Effects
- Diarrhea
- Prolonged QT Interval
- P450 Inhibitor
- Cholestatic Hepatitis
- Skin Rash
- Eosinophilia
3 mins
Nocardia
- Characteristics
- Aerobic
- Gram-Positive
- Catalase-Positive
- Urease-Positive
- Acid Fast
- Branching
- Beaded Filament
- AIDS/Immunocompromised
- Soil
- Signs and Symptoms
- Lung Cavitation
- Brain Abscess
- Kidney Abscess
- Treatment
- TMP-SMX
2 mins
Aminoglycoside Overview
- End in "-mycin"
- GNATS
- Gentamicin
- Neomycin
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Indications
- Severe Gram Negative Infections
- Bowel Surgery Prep
1 min
Aminoglycoside Side Effects
- Side Effects
- Ototoxicity
- Nephrotoxicity
- Respiratory Paralysis
- Contraindications
- Pregnancy
- Considerations
- Peak and Trough
- Never Mix with Penicillin in Same IV
2 mins
Neomycin Sulfate
- Mechanism
- Aminoglycoside Antibiotic
- Indications
- Topical Infection
- Intestinal Surgery Prophylaxis
- Side Effects
- Ototoxicity
- Nephrotoxicity
- Rash
- Blood Dyscrasias
- Considerations
- GI Superinfection
2 mins
Killed (Inactivated) Whole Vaccines
- Characteristics
- Require Booster Shots
- Vaccines
- Mostly Humoral Immune Response
- Polio (Salk)
- Rabies
- Cholera
- Hepatitis A
54 secs
Chloramphenicol (Chloromycetin)
- Mechanism
- Bacteriostatic
- Indications
- Gram Positive or Gram Negative Infections
- Side Effects
- Bone Marrow Suppression
- Aplastic Crisis
- Gray Syndrome
- Considerations
- Toxicity Limits Use
- Monitor Blood Counts
2 mins
Live Attenuated Vaccines
- Characteristics
- Humoral and Cellular Immune Response
- May Revert to Virulent Form
- Do Not Require Boosters
- Vaccines
- Varicella (Chickenpox)
- Zoster (Shingles)
- Polio (Sabin)
- Smallpox
- Yellow Fever
- Influenza (Intranasal)
- MMR
- Rotavirus
- Typhoid Fever (Oral)
- BCG (Bacillus Calmette-Guérin)
4 mins
Tetracyclines Overview
- End in "-cycline"
- Mechanism of Action
- Bacteriostatic
- Indications
- Infectious Diseases
- Acne
- Periodontal Disease
- Nursing Considerations
- Avoid Milk, Antacids, Iron
- Sunlight Protection
1 min
Killed (Inactivated) Fractional Protein Vaccines
- Subunit Vaccines
- Subunit
- Influenza (Intramuscular)
- Bordetella Pertussis
- Hepatitis B
- Human Papillomavirus (HPV)
- Bacillus anthracis (Anthrax)
- Toxoid Vaccines
- Toxoid
- Corynebacterium diphtheriae (Diphtheria)
- Clostridium tetani (Tetanus)
- Considerations
- DTaP and Tdap
3 mins
Tetracyclines Side Effects
- Side Effects
- Superinfection
- Clostridioides difficile
- Discoloration of Teeth
- Bone Deformities
- Photosensitivity
- Contraindications
- Children Under 8
- Pregnancy
1 min
Toxoid Vaccines
- Consist of Toxins Released From a Pathogen
- May Require Boosters
- Safe In Immunocompromised Patients
- Corynebacterium Diphtheriae Vaccine
- Tetanus Vaccine
- Bordetella Pertussis Vaccine
2 mins
Tetracycline Toxicities
- Inhibition of Bone Growth in Children
- Teratogen
- Discoloration of Teeth
- Photosensitivity
- GI Distress
2 mins
Somatostatin
- Secreted by D Cells
- Pancreas
- GI Tract
- Action
- Decrease Secretion of Gastric Acid and Pepsinogen
- Decrease Pancreatic and Small Intestine Fluid Secretion
- Decrease Gallbladder Contraction
- Decrease Glucagon and Insulin Secretion
- Regulation
- Secretion is Increased by Acid
- Secretion is Decreased by Vagal Stimulation
- Clinical Use
- Octreotide
- Carcinoid Syndrome
- Variceal Bleeds
2 mins
Tigecycline (Tygacil)
- Mechanism Of Action
- Glycylcycline Antibiotic
- Binds 30S Subunit
- Inhibits Protein Synthesis
- Indications
- Severe Infections
- Broad Spectrum Coverage
- Anaerobic & Multidrug-Resistant Organisms
- Deep Tissue Penetration
- Side Effects
- GI Distress
- Severe Nausea and Vomiting
- Considerations
- 2nd Line Agent
3 mins
Fluoroquinolones
- End in "-floxacin"
- Mechanism of Action
- Bactericidal
- Indications
- Variety of Infections
- Side Effects
- GI Distress
- Photosensitivity
- Achilles Tendon Rupture
- Contraindications
- Pregnancy
- Children
- Myasthenia Gravis
- Considerations
- Avoid Milk Products or Antacids
- Slow IV Infusion
2 mins
Fluoroquinolones Toxicities
- Diarrhea
- Skin Rash
- Headache
- Tendon Rupture in Adults
- Myalgias in Kids
- Damage to Cartilage
- Teratogen
- QT Prolongation
1 min
Vancomycin Side Effects & Toxicity
- Side Effects
- Thrombophlebitis
- Nephrotoxicity
- Ototoxicity
- Diffuse Flushing Called Red Man Syndrome
- Prevent with Antihistamine
- Prevent with Slow Infusion
2 mins
Vancomycin
- Mechanism of Action
- Inhibits Bacterial Cell Wall Synthesis
- Indications
- Serious Gram-Positive Infections
- Side Effects
- Nephrotoxicity
- Ototoxicity
- Red Man Syndrome
- Thrombophlebitis
- Nursing Considerations
- Culture Samples First
- Infuse IV Over 60 Minutes
- Take Around the Clock
2 mins
Linezolid (Zyvox)
- Mechanism Of Action
- Oxazolidinone Antibiotic
- Binds 23S rRNA of 50S Subunit
- Inhibits Protein Synthesis
- Indication
- Gram-Positive Organisms
- MRSA
- VRE (Vancomycin Resistant Enterococci)
- Side Effects
- Bone Marrow Suppression
- Decreased Platelet Count
- Peripheral Neuropathy
- Lactic Acidosis
- Serotonin Syndrome
- Considerations & Patient Education
- Avoid Tyramine Containing Foods
4 mins
Clindamycin
- Mechanism
- Bacteriostatic
- Binds 50S Ribosomal Subunit
- Indications
- Gram-Positive Infections
- Anaerobic Infections
- Side Effects
- Rash
- Pseudomembranous Colitis
- C. Difficile (Associated Diarrhea)
- Arrhythmias
- Blood Dyscrasias
- Considerations
- Monitor for Diarrhea
3 mins
Sulfonamides
- Mechanism of Action
- Bacteriostatic
- Indications
- Urinary Tract Infection
- Side Effects
- Crystalluria
- Photosensitivity
- Hemolytic Anemia
- Kernicterus
- Rash
- Considerations
- Sulfa Allergy
- Encourage Fluids
2 mins
Sulfonamides Side Effects
- Side Effects
- Hypersensitivity
- Nephrotoxicity
- Photosensitivity
- Kernicterus in Infants
- Displaces Warfarin from Albumin
- Considerations
- Hemolysis with G6PD Deficiency
3 mins
Sulfa Drug Allergies
- Sulfasalazine
- Sulfonylureas
- Thiazide Diuretics
- Acetazolamide
- Furosemide Diuretic
- Celecoxib
- Probenecid
49 secs
Daptomycin (Cubicin)
- Mechanism Of Action
- Lipopeptide Antibiotic
- Disrupts Cell Membrane
- Causes Rapid Depolarization
- Indication
- Gram-Positive Cocci
- MRSA
- Side Effects
- Myopathy
- Rhabdomyolysis
- Peripheral Neuropathy
- Considerations & Patient Education
- Inactivated by Surfactant
- Not Used (Avoid) for Pneumonia
3 mins
Trimethoprim
- Mechanism of Action
- Bacteriostatic
- Inhibits Bacterial Dihydrofolate Reductase
- Causes Sequential Block of Folate Synthesis
- Used in Combination with Sulfamethoxazole
- Combination Used For Recurrent Urinary Tract Infections
- Indications
- Shigella
- Salmonella
- Pneumocystis Jiroveci Pneumonia
- Side Effects
- Decrease in Red and White Blood Cells
- Alleviated with Leucovorin Rescue
2 mins
Acyclovir (Zovirax)
- Mechanism
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Indications
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Side Effects (Oral)
- Headache
- GI Distress
- Side Effects (IV)
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Considerations
- Prevents Recurrent Episodes
- Slow IV Infusion
2 mins
HAART
- HIV
- Begin at Diagnosis
- 3 Drugs
- 2 NRTIs (Nucleoside Reverse Transcriptase Inhibitors)
- And one of the following:
- NNRTI (Non-Nucleoside Reverse Transcriptase Inhibitor)
- or Protease Inhibitor
- or Integrase Inhibitor
1 min
NNRTI Drug Names
- Nevirapine (Viramune)
- Rilpivirine (Edurant)
- Delavirdine (DLV, Rescriptor)
- Efavirenz (EFV, Sustiva)
- Etravirine (ETR, Intelence)
54 secs
NRTIs for HIV (Drug Names)
- Nucleoside Analog
- DEALSZ
- Didanosine (DDI)
- Emtricitabine (FTC)
- Abacavir (ABC)
- Lamivudine (3TC)
- Stavudine (d4T)
- Zidovudine (ZDV)
- Nucleotide Analog
- Tenofovir (TDF)
2 mins
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