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Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker
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Chapter 12: Antiprotozoal Agents

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Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker | Registered Nurse (RN) School Study Aid

Chapter 12: Antiprotozoal Agents
8 Picmonics to Learn | 17 mins
Hydroxychloroquine
Mechanism of Action
Immunosuppressant
Indications
Malaria
Rheumatoid Arthritis
Systemic Lupus Erythematosus (SLE)
Porphyria Cutanea Tarda
Side Effects
Cardiotoxicity
Retinopathy
Considerations
Ophthalmological Exams
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3 mins
Babesia
Characteristics
Protozoa
Ixodes Tick
Same vector as Borrelia
Northeastern US
Asplenia
Signs and Symptoms
Fever
Hemolytic Anemia
Diagnosis
Blood Smear
Maltese Cross
Treatments
Atovaquone
Azithromycin
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3 mins
Metronidazole
Mechanism of Action
Bactericidal
Forms Free Radical Toxic Metabolites
Damages DNA
Indications
Giardia lamblia
Entamoeba Histolytica
Trichomonas
Gardnerella
Anaerobes
Side Effects
Metallic taste
Disulfiram like Reaction with Alcohol
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2 mins
Clostridium difficile (Clostridioides difficile) Treatments
Oral Vancomycin
Fidaxomicin
Metronidazole
Stool Transplant
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2 mins
Giardia lamblia
Characteristics
Protozoa
Ingestion of Cysts
Seen in Campers
Daycare Centers
Mental Hospitals
Infects Small Intestine
Signs and Symptoms
Bloating
Flatulence
Fatty Diarrhea
Diagnosis
Crescent-shaped Protozoa Adjacent to Epithelial Brush Border
Predisposed if Low IgA
Treatment
Metronidazole
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3 mins
Cryptosporidium
Characteristics
Protozoa
Ingestion of Oocysts in Food or Water
Acid Fast Cysts
Signs and Symptoms
Outbreaks of Diarrhea from Contaminated Water Supply
Mild Disease in Non-immunocompromised
Severe Diarrhea in AIDS
Treatment
Nitazoxanide for Immunocompetent
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2 mins
Vaginitis
Cause/Mechanism
Infection
Postmenopausal Atrophy
Assessment
Vaginal Discharge
Pruritus
Interventions
Antifungals (Miconazole, Clotrimazole)
Antibiotics
Estrogen Hormones
Abstinence
Considerations
Good Hygiene
Recurrent Vaginitis
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2 mins
Trichomonas vaginalis
Characteristics
Protozoa
Signs and Symptoms
Vaginitis
Pruritus
Foul-smelling Greenish Frothy Discharge
Strawberry Cervix
Diagnosis
Corkscrew Motility on Wet Prep
Treatment
Metronidazole
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2 mins

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